3-Methylcatechol is a chemical compound with various applications in everyday life. It is commonly used in the synthesis of pharmaceuticals, fragrances, and dyes. In the pharmaceutical industry, 3-Methylcatechol is employed in the production of drugs for treating cardiovascular diseases, as well as in the synthesis of antibiotics and antiviral medications. Additionally, this compound is utilized in the formulation of perfumes and flavors due to its aromatic properties. Moreover, it serves as a precursor for the production of dyes used in textiles and paints. Consequently, 3-Methylcatechol plays a crucial role in numerous consumer products, making it a significant component in our daily lives.
Table of Contents:
Commercial Applications
Chemical & Physical Properties
Production & Procurement
Safety Considerations
Potential Research Directions
Related Compounds
Commercial Applications
3-Methylcatechol, also known as meta-methylcatechol or 3-hydroxytoluene, has various commercial and industrial applications. It is commonly used as a precursor in the production of pharmaceuticals, agrochemicals, and fragrances due to its reactivity and versatile chemical properties. Additionally, 3-Methylcatechol is utilized as a monomer in the synthesis of polymers and as a reducing agent in the manufacturing of dyes and pigments.
In the realm of drug and medication applications, 3-Methylcatechol plays a significant role in the pharmaceutical industry. This compound is a key intermediate in the synthesis of important pharmaceutical drugs, such as cardiovascular medications and antihistamines. Furthermore, its antioxidant properties make it valuable in formulations designed to counteract oxidative stress in various medical conditions.
Overall, 3-Methylcatechol is a compound with a wide range of commercial, industrial, and pharmaceutical applications. Its synthesis and utilization form an essential part of the production process in diverse industries, contributing to the development of valuable products and formulations for various purposes.
Chemical & Physical Properties
3-Methylcatechol is a white to slightly yellow crystalline solid with a faint odor. It is typically present in a solid form at room temperature and is sparingly soluble in water.
With a molar mass of 138.14 g/mol and a density of 1.135 g/cm^3, 3-Methylcatechol is relatively lighter and less dense than many common household items, such as water (molar mass: 18.015 g/mol, density: 1 g/cm^3) and table salt (molar mass: 58.44 g/mol, density: 2.16 g/cm^3).
The melting point of 3-Methylcatechol is around 96-98°C, while the boiling point is approximately 261-262°C. These values are much higher compared to common household items like ice (melting point: 0°C) and water (boiling point: 100°C).
3-Methylcatechol is soluble in water to a limited extent, forming a clear solution. It exhibits relatively low viscosity, making it less viscous compared to substances like honey or corn syrup commonly found in households.
Production & Procurement
3-Methylcatechol is typically produced through the methylation of catechol using methyl iodide or dimethyl sulfate as the methylating agent. This reaction is catalyzed by a base such as sodium hydroxide or potassium hydroxide. The resulting product is then purified through techniques such as distillation or chromatography to isolate the 3-Methylcatechol compound.
The procurement of 3-Methylcatechol can be achieved through chemical suppliers or specialty manufacturers who produce and distribute this compound. It can be transported in solid or liquid form, depending on the preferences of the customer. Due to its stability under certain conditions, 3-Methylcatechol can be safely transported via standard shipping methods without the need for specialized handling or storage.
When procuring 3-Methylcatechol for research or industrial purposes, it is important to ensure that the product obtained meets the required specifications and purity levels. This can be done through the use of certificates of analysis provided by the manufacturer, which detail the composition and quality of the 3-Methylcatechol compound. Additionally, proper storage and handling procedures should be followed to maintain the integrity of the product during transport and storage.
Safety Considerations
Safety considerations for 3-Methylcatechol include its potential for skin and eye irritation. It is important to handle this compound with care, wearing appropriate personal protective equipment such as gloves and safety goggles. In case of contact with skin or eyes, it is recommended to rinse thoroughly with water and seek medical attention if necessary. Additionally, 3-Methylcatechol should be stored in a cool, dry place away from sources of ignition or heat.
The pharmacology of 3-Methylcatechol involves its role as a metabolic intermediate in the breakdown of certain aromatic compounds. This compound is known to undergo oxidation in the body, leading to the formation of reactive oxygen species. Studies have shown that excessive exposure to 3-Methylcatechol can have deleterious effects on cellular function and may contribute to oxidative stress.
Hazard statements for 3-Methylcatechol include its classification as a skin and eye irritant. This compound has the potential to cause irritation upon contact with skin or eyes, leading to redness, swelling, and discomfort. It is important to handle 3-Methylcatechol with caution and take appropriate measures to prevent exposure to these sensitive areas of the body.
Precautionary statements for 3-Methylcatechol include recommendations for safe handling and storage. It is advised to use this compound in a well-ventilated area to minimize the risk of inhalation exposure. When handling 3-Methylcatechol, it is important to wear suitable protective clothing and equipment to prevent skin and eye contact. Additionally, proper storage of this compound in a tightly sealed container away from incompatible materials is crucial to ensure safe handling practices.
Potential Research Directions
One potential research direction for 3-Methylcatechol lies in its role as a precursor in the synthesis of natural products such as alkaloids and lignans. Investigating the enzymatic pathways involved in the biosynthesis of these compounds could provide valuable insights into the mechanisms underlying their formation.
Furthermore, the potential bioactivity of 3-Methylcatechol and its derivatives could be explored in the context of drug discovery and development. Investigating the pharmacological properties of these compounds may uncover novel therapeutic applications in areas such as cancer treatment and antimicrobial activity.
Additionally, the environmental fate and behavior of 3-Methylcatechol in natural systems could be a fruitful area of research. Studies on its degradation pathways and interactions with other environmental contaminants could shed light on its potential impact on ecosystems and human health.
Related Compounds
One similar compound to 3-Methylcatechol based upon molecular structure is 4-Methylcatechol. This compound differs from 3-Methylcatechol by the position of the methyl group on the benzene ring, with the methyl group located at the 4-position instead of the 3-position. This change in position alters the chemical properties and biological activities of the compound.
Another similar compound to 3-Methylcatechol is 2-Methylcatechol. In this compound, the methyl group is located at the 2-position on the benzene ring, resulting in different steric effects and electronic properties compared to 3-Methylcatechol. This subtle difference in structure can have significant impacts on the compound’s reactivity and interactions with other molecules.
Additionally, 3,5-Dimethylcatechol is another compound that shares similarities with 3-Methylcatechol. In this compound, two methyl groups are present on the benzene ring, at the 3- and 5-positions. This structural arrangement results in unique properties and potential biological activities that distinguish it from both 3-Methylcatechol and other similar compounds. Understanding the subtle variations in structure among these compounds can provide valuable insights into their behavior and potential applications in various fields.
