3-dehydro-L-gulonic acid is a crucial precursor in the synthesis of vitamin C, also known as ascorbic acid. Vitamin C is an essential nutrient for humans, playing a critical role in various bodily functions such as collagen production, iron absorption, and immune system support. Therefore, the importance of 3-dehydro-L-gulonic acid lies in its contribution to the overall health and well-being of individuals in their daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Dehydro-L-gulonic acid, commonly known as 3-DKG, is primarily used in the commercial and industrial sectors for the synthesis of vitamin C, also known as ascorbic acid. This compound serves as a key intermediate in the multistep biosynthesis of ascorbic acid and is crucial for the production of this essential nutrient. The commercial applications of 3-DKG are primarily centered around its role in the vitamin C industry, where it is used as a precursor for the synthesis of this important vitamin.
In addition to its commercial and industrial applications, 3-DKG also plays a significant role in the field of drug and medication development. Due to its role in the biosynthesis of ascorbic acid, 3-DKG is a key compound in the production of various vitamin C supplements and pharmaceutical formulations. Furthermore, recent research has explored the potential therapeutic applications of 3-DKG in the treatment of various health conditions, including vitamin C deficiencies and oxidative stress-related diseases. The medicinal properties of 3-DKG make it a valuable compound in the development of novel drug treatments and pharmaceutical products.
Overall, the commercial and industrial applications of 3-DKG are primarily focused on its role as a precursor for the synthesis of ascorbic acid, while its drug and medication applications center around the development of vitamin C supplements and pharmaceutical formulations. The versatility of 3-DKG in these various industries highlights its importance as a key intermediate in the production of essential nutrients and therapeutic compounds. Further research and development in the field of 3-DKG utilization are expected to yield additional insights into its potential applications in commercial, industrial, and medicinal settings.
⚗️ Chemical & Physical Properties
3-Dehydro-L-gulonic acid is a white, crystalline solid with no distinct odor. It is a stable compound at room temperature and does not readily degrade.
The molar mass of 3-dehydro-L-gulonic acid is approximately 176.13 g/mol, with a density of 1.892 g/cm³. In comparison to common food items, 3-dehydro-L-gulonic acid has a higher molar mass than glucose (180.16 g/mol) but a lower density than sugar (1.59 g/cm³).
The melting point of 3-dehydro-L-gulonic acid is around 177-179°C, while the boiling point is approximately 250-252°C. Compared to common food items, 3-dehydro-L-gulonic acid has a higher melting point than butter (around 32-35°C) and a lower boiling point than water (100°C).
3-Dehydro-L-gulonic acid is highly soluble in water, forming a clear and colorless solution. It exhibits low viscosity, with a thin and watery consistency. In contrast to common food items, 3-dehydro-L-gulonic acid has higher solubility in water than sugar and lower viscosity than honey.
🏭 Production & Procurement
Production of 3-dehydro-L-gulonic acid involves a multi-step enzymatic process that begins with the conversion of glucose to sorbitol. Sorbitol is then oxidized to form 3-dehydro-L-gulonic acid, which is further purified through chromatography.
To procure 3-dehydro-L-gulonic acid, one might turn to specialized chemical companies that produce and distribute this compound. It is often available for purchase in both liquid and powder forms, suitable for a variety of applications in the pharmaceutical and food industries.
Transportation of 3-dehydro-L-gulonic acid typically involves shipping in carefully controlled conditions to ensure the stability and purity of the compound. Companies may use specialized carriers equipped to handle hazardous materials or sensitive chemicals to ensure safe and reliable delivery.
⚠️ Safety Considerations
Safety considerations for 3-dehydro-L-gulonic acid should be taken seriously due to its potential hazards. When handling this compound, it is important to wear appropriate personal protective equipment such as gloves, goggles, and lab coat to prevent skin contact and inhalation of vapors. In addition, one should work with 3-dehydro-L-gulonic acid in a well-ventilated area to minimize exposure to harmful fumes.
The hazard statements for 3-dehydro-L-gulonic acid include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements indicate the potential risks associated with direct contact with the compound on skin, eyes, and lungs. It is important to handle 3-dehydro-L-gulonic acid with caution and take necessary precautions to avoid these hazards.
Precautionary statements for 3-dehydro-L-gulonic acid include “Wear protective gloves/eye protection/face protection,” “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.” and “IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.” These statements provide guidance on how to safely handle 3-dehydro-L-gulonic acid in case of exposure to skin, eyes, or inhalation. Following these precautions is crucial to ensuring the well-being of individuals working with this compound.
🔬 Potential Research Directions
One potential research direction for 3-dehydro-L-gulonic acid involves investigating its role as a precursor in the synthesis of vitamin C, also known as ascorbic acid.
Furthermore, researchers may explore the enzymatic pathways involved in the biosynthesis of 3-dehydro-L-gulonic acid, shedding light on the molecular mechanisms underlying its production in various organisms.
Additionally, studies could focus on the potential therapeutic applications of 3-dehydro-L-gulonic acid, such as its use in the development of novel drugs targeting conditions related to vitamin C deficiency.
🧪 Related Compounds
One similar compound to 3-dehydro-L-gulonic acid based upon molecular structure is 2-dehydro-L-gulonic acid. This compound is structurally similar to 3-dehydro-L-gulonic acid, but differs in the position of the double bond. The presence of the double bond in both compounds gives them similar chemical properties.
Another compound that is structurally similar to 3-dehydro-L-gulonic acid is L-gulonic acid. This compound differs from 3-dehydro-L-gulonic acid by having a hydroxyl group in place of the double bond. Despite this difference, both compounds belong to the same family of sugars and share some similar chemical properties.
One more compound with a molecular structure similar to 3-dehydro-L-gulonic acid is L-ascorbic acid. This compound is a derivative of L-gulonic acid and also contains a hydroxyl group in place of the double bond. L-ascorbic acid is better known as vitamin C and plays a crucial role in various biochemical processes in the body.
