2-Deoxy-D-glucose is a glucose analog that has garnered attention for its potential applications in various fields, including cancer research and metabolic disorders. In everyday life, this compound could hold promise as a tool for exploring new therapies for diseases such as cancer, as well as for elucidating the mechanisms underlying glucose metabolism in the body. Additionally, research on 2-Deoxy-D-glucose may lead to insights that could ultimately impact public health by informing the development of novel treatments for a range of medical conditions.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-deoxy-D-glucose, a glucose analogue, has found various commercial and industrial applications. It is commonly used in research as a probe for sugar transport and metabolism studies. Additionally, it has been utilized in the food industry to inhibit browning reactions and extend the shelf life of certain products.
In terms of drug and medication applications, 2-deoxy-D-glucose has shown promise as a potential cancer treatment. Studies have indicated that it can inhibit tumor growth by disrupting glucose metabolism in cancer cells. Additionally, it is being investigated for its potential to enhance the efficacy of traditional cancer therapies, such as radiation and chemotherapy.
Overall, the commercial and industrial applications of 2-deoxy-D-glucose are diverse and continue to expand as research on its properties and potential benefits progresses. Its unique properties make it a valuable tool in various fields, from biotechnology to food science. In the realm of drug development, it holds promise as a novel approach to combating cancer and improving the outcomes of traditional treatments.
⚗️ Chemical & Physical Properties
2-deoxy-D-glucose is a white crystalline powder that is odorless. It does not exhibit any discernible odor when in its pure form.
The molar mass of 2-deoxy-D-glucose is approximately 164.16 g/mol, with a density of about 1.54 g/cm³. This places it in the range of common food items in terms of molar mass and density, although it may vary slightly depending on the specific food item being compared.
The melting point of 2-deoxy-D-glucose is around 146-147°C, while its boiling point is approximately 424-425°C. These values are within the typical range of common food items, although they may be slightly higher compared to some food compounds.
2-deoxy-D-glucose is readily soluble in water and has a low viscosity. When compared to common food items, it exhibits similar solubility in water but may have a lower viscosity in some cases.
🏭 Production & Procurement
2-deoxy-D-glucose is typically produced through chemical synthesis in a laboratory setting. This process involves the conversion of D-glucose to 2-deoxy-D-glucose by removing the hydroxyl group at the C-2 position. The resulting compound is then purified and isolated for further use in research or other applications.
The procurement of 2-deoxy-D-glucose can be achieved through specialized chemical suppliers or pharmaceutical companies. These entities may offer the compound in various forms, such as powder or solution, depending on the intended use. Once procured, 2-deoxy-D-glucose can be transported in sealed containers to ensure its stability and purity during transit.
Transportation of 2-deoxy-D-glucose typically involves standard shipping methods, such as ground or air freight, depending on the distance and urgency of delivery. The compound should be handled with care to prevent contamination or degradation, as it is sensitive to moisture and impurities. Proper labeling and documentation are essential to ensure compliance with regulations and safe handling practices.
⚠️ Safety Considerations
Safety considerations for 2-deoxy-D-glucose involve handling the substance with care due to its potential health hazards. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when working with 2-deoxy-D-glucose to prevent skin contact and inhalation of the substance. Proper ventilation should also be ensured to minimize exposure to the chemical.
Hazard statements for 2-deoxy-D-glucose include “Causes skin irritation” and “May cause respiratory irritation.” These statements indicate that direct contact with the skin or inhalation of the substance can result in irritation. It is important to take necessary precautions to avoid exposure and minimize the risk of adverse effects on health.
Precautionary statements for 2-deoxy-D-glucose include “Avoid breathing dust/fume/gas/mist/vapors/spray” and “Wear protective gloves/protective clothing/eye protection/face protection.” These statements emphasize the importance of proper ventilation and personal protective equipment when handling 2-deoxy-D-glucose to reduce the risk of exposure and potential harm. It is essential to follow these precautions to ensure safe handling and use of the chemical.
🔬 Potential Research Directions
One potential research direction for 2-deoxy-D-glucose is further investigation into its potential as a cancer therapy. Studies have shown that 2-deoxy-D-glucose can inhibit tumor growth by targeting the glucose metabolism of cancer cells. Future research could explore its efficacy in combination with other cancer treatments or in different types of cancer.
Another area of research could focus on the neuroprotective effects of 2-deoxy-D-glucose. Studies have suggested that 2-deoxy-D-glucose may have the potential to reduce neuronal damage and improve cognitive function in neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Further research could elucidate the underlying mechanisms of this neuroprotective effect and explore its therapeutic potential in treating these debilitating conditions.
🧪 Related Compounds
One similar compound to 2-deoxy-D-glucose based on molecular structure is 2-deoxy-D-galactose. 2-deoxy-D-galactose is a monosaccharide that is structurally similar to 2-deoxy-D-glucose, with the exception that the sixth carbon atom contains a hydroxyl group in 2-deoxy-D-galactose instead of a hydrogen atom. This compound is commonly found in glycoproteins and glycolipids in biological systems.
Another related compound to 2-deoxy-D-glucose is 2-deoxy-D-mannose. This monosaccharide has a similar molecular structure to 2-deoxy-D-glucose, with the exception that the stereochemistry of the hydroxyl group at the second carbon atom is different. 2-deoxy-D-mannose is involved in various metabolic pathways and is an important precursor for the synthesis of complex carbohydrates in cells.
Finally, 2-deoxy-D-ribose is also a compound that shares a similar molecular structure to 2-deoxy-D-glucose. 2-deoxy-D-ribose is a monosaccharide that differs from 2-deoxy-D-glucose in the configuration of the hydroxyl group at the second carbon atom. This compound is a component of DNA and RNA molecules, playing a crucial role in genetic information transmission and storage in organisms.
