Diethyl 2-methyl-3-oxosuccinate, while not a household name to the general public, plays a crucial role in various industries. This compound is commonly used in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Its versatile properties make it a key component in the production of medications, pesticides, and perfumes, impacting the everyday lives of individuals worldwide. Additionally, the research and development of compounds like Diethyl 2-methyl-3-oxosuccinate contribute to advancements in science and technology, ultimately benefiting society as a whole.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Diethyl 2-methyl-3-oxosuccinate, a chemical compound commonly used in the manufacturing industry, has various commercial and industrial applications. It is often utilized as an intermediate in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatile nature allows it to serve as a building block in the synthesis of complex molecules, making it valuable in numerous industries.
In drug and medication applications, Diethyl 2-methyl-3-oxosuccinate plays a crucial role as a key intermediate in the synthesis of various pharmaceutical products. It is commonly used in the production of active pharmaceutical ingredients (APIs) due to its ability to contribute specific functional groups needed for the desired pharmacological activity. This compound is essential in the creation of medications that target specific diseases and disorders, showcasing its significance in the pharmaceutical industry.
Furthermore, Diethyl 2-methyl-3-oxosuccinate is employed in the formulation of medications that require precise synthesis and control of chemical reactions. Its stability and reactivity attributes make it an ideal choice for drug manufacturers seeking to produce high-quality pharmaceutical products. Additionally, its compatibility with other chemical compounds allows for enhanced drug delivery systems and improved therapeutic outcomes in various medical treatments.
⚗️ Chemical & Physical Properties
Diethyl 2-methyl-3-oxosuccinate is a colorless liquid with a faint, fruity odor.
With a molar mass of approximately 196.22 g/mol and a density of about 1.05 g/cm^3, Diethyl 2-methyl-3-oxosuccinate is much lighter than common food items like sugar (342.3 g/mol, 1.587 g/cm^3) and salt (58.44 g/mol, 2.165 g/cm^3).
The compound has a melting point of around -25°C and a boiling point of approximately 180°C, making it significantly lower in comparison to common food items such as butter (melting point: 32-35°C, boiling point: 150-180°C) and olive oil (melting point: -6°C, boiling point: 240°C).
Diethyl 2-methyl-3-oxosuccinate is sparingly soluble in water and exhibits a low viscosity. This contrasts with common food items like sugar and salt, which are highly soluble in water and have a much higher viscosity.
🏭 Production & Procurement
Diethyl 2-methyl-3-oxosuccinate is typically produced through a multi-step chemical reaction process involving the esterification of ethyl acetoacetate with the corresponding alcohol. This reaction is commonly carried out using acidic catalysts in order to promote the formation of the desired product.
Once the Diethyl 2-methyl-3-oxosuccinate is produced, it can be procured from chemical suppliers specializing in the distribution of fine chemicals and specialty reagents. The compound is typically available in both bulk quantities for industrial applications and smaller quantities for research purposes.
In terms of transportation, Diethyl 2-methyl-3-oxosuccinate is classified as a hazardous material due to its flammability and potential health hazards. Therefore, it must be packaged and shipped in accordance with regulations set forth by government agencies such as the Department of Transportation and the International Air Transport Association.
⚠️ Safety Considerations
Safety considerations for Diethyl 2-methyl-3-oxosuccinate should be taken seriously due to its potential hazards. This compound is flammable and can release flammable vapors when exposed to heat or flame. It may also cause skin irritation upon contact and is harmful if swallowed or inhaled. Therefore, proper handling procedures, such as wearing protective clothing and working in a well-ventilated area, are crucial to ensure safety when dealing with Diethyl 2-methyl-3-oxosuccinate.
Hazard statements for Diethyl 2-methyl-3-oxosuccinate include “Causes skin irritation,” “Harmful if swallowed,” “Harmful if inhaled,” and “May cause respiratory irritation.” These statements indicate the potential dangers associated with this compound and emphasize the importance of following proper safety protocols when working with it. It is essential to minimize exposure by using protective equipment and working in a controlled environment to prevent any harm.
Precautionary statements for Diethyl 2-methyl-3-oxosuccinate include “Avoid breathing dust/fume/gas/mist/vapors/spray,” “Wear protective gloves/protective clothing/eye protection/face protection,” and “IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.” These statements provide specific guidelines for handling this compound safely and outline the necessary precautions to minimize risks. By following these precautionary measures, individuals can reduce the likelihood of accidents or injuries when working with Diethyl 2-methyl-3-oxosuccinate.
🔬 Potential Research Directions
Research on Diethyl 2-methyl-3-oxosuccinate could investigate its potential use as a building block in organic synthesis, particularly in the preparation of pharmaceutical compounds. Further studies may explore its reactivity with various nucleophiles and electrophiles to understand its reaction mechanisms and potential applications in complex molecule synthesis.
Additionally, investigations into the stability and reactivity of Diethyl 2-methyl-3-oxosuccinate under different conditions could provide valuable insights into its practical utility. This could involve studying its behavior in the presence of different solvents, temperatures, and catalysts to optimize its synthetic potential and create new avenues for its use in chemical transformations.
Furthermore, research may explore the spectroscopic properties of Diethyl 2-methyl-3-oxosuccinate to aid in its identification and characterization in chemical reactions. This could involve using techniques such as NMR, IR, and mass spectrometry to elucidate its structure, confirm its purity, and track its transformations in various synthetic pathways.
🧪 Related Compounds
One similar compound to Diethyl 2-methyl-3-oxosuccinate is Diethyl 2-methylmalonate. This compound has a similar molecular structure, with a 2-methyl group attached to the carbon chain. Both compounds contain two ester groups and a ketone group. Diethyl 2-methylmalonate is commonly used in organic synthesis as a building block for various compounds.
Another compound with a molecular structure similar to Diethyl 2-methyl-3-oxosuccinate is Diethyl 2-methylglutarate. This compound also contains a 2-methyl group on the carbon chain and two ester groups. Diethyl 2-methylglutarate is used in organic synthesis for the production of various chemicals and pharmaceuticals due to its versatile reactivity.
Ethyl 2-methyl-3-oxobutanoate is another compound that shares similarities with Diethyl 2-methyl-3-oxosuccinate. Both compounds contain a 2-methyl group and a ketone group. Ethyl 2-methyl-3-oxobutanoate is commonly used as a precursor in the synthesis of pharmaceuticals and fragrances. Its structural similarity to Diethyl 2-methyl-3-oxosuccinate allows for similar reactivity in chemical reactions.
