2-Chloro-1,4-naphthoquinone, also known as Cl-NQ, is a chemical compound that has various applications in everyday life. It is commonly used in the production of dyes, pharmaceuticals, and pesticides. Additionally, Cl-NQ is known for its antitumor and antibacterial properties, making it a key ingredient in some medical treatments. Overall, the relevance of 2-Chloro-1,4-naphthoquinone lies in its versatility and importance in multiple industries that impact our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Chloro-1,4-naphthoquinone, also known as Cl-NQ, has several commercial and industrial applications. It is commonly used as a precursor in the production of dyes, pigments, and pharmaceutical compounds. It is also utilized in the manufacture of insecticides, fungicides, and herbicides due to its pesticidal properties.
In addition to its commercial and industrial uses, 2-Chloro-1,4-naphthoquinone is also employed in the pharmaceutical industry for drug and medication applications. It is commonly used as an intermediate in the synthesis of various medications, including antimalarial drugs and anticancer agents. Its ability to inhibit the growth of cancer cells makes it a valuable component in chemotherapy treatments.
Overall, 2-Chloro-1,4-naphthoquinone plays a crucial role in various industries, from dye production to pharmaceutical development. Its versatile applications make it a valuable compound in the commercial, industrial, and medical sectors.
⚗️ Chemical & Physical Properties
2-Chloro-1,4-naphthoquinone appears as a pale yellow solid with a strong, pungent odor.
The molar mass of 2-Chloro-1,4-naphthoquinone is 216.62 g/mol, and its density is 1.52 g/cm³. These values are significantly higher than common food items, such as water (molar mass of 18.02 g/mol, density of 1.00 g/cm³).
The melting point of 2-Chloro-1,4-naphthoquinone is approximately 105-107°C, while the boiling point is around 299-301°C. These values are much higher than common food items, such as sugar (melting point of 186°C, boiling point of 186°C).
2-Chloro-1,4-naphthoquinone is sparingly soluble in water, and exhibits a high viscosity. This contrasts with common food items, which are typically highly soluble in water and have lower viscosities.
🏭 Production & Procurement
2-Chloro-1,4-naphthoquinone, also known as Clawsone, is primarily produced through the chlorination of 1,4-naphthoquinone. This process involves the reaction of 1,4-naphthoquinone with a chlorine source, such as chlorine gas or sodium hypochlorite, in the presence of a suitable catalyst. The chlorination reaction typically takes place under controlled conditions, with careful monitoring of temperature and reaction time to ensure high yields of 2-Chloro-1,4-naphthoquinone.
In terms of procurement, 2-Chloro-1,4-naphthoquinone can be obtained from chemical suppliers who specialize in the production and distribution of specialty chemicals. The compound is typically available in both solid and liquid forms, depending on the specific requirements of the end user. Due to its high reactivity and potential health hazards, proper handling and storage procedures must be followed when transporting and storing 2-Chloro-1,4-naphthoquinone. Additionally, appropriate safety precautions should be taken to minimize the risk of exposure and accidental release during transportation.
⚠️ Safety Considerations
Safety considerations for 2-Chloro-1,4-naphthoquinone, also known as chloro-1,4-naphthoquinone, include the potential for skin and eye irritation, as well as respiratory irritation if inhaled. This compound should be handled in a well-ventilated area, and personal protective equipment such as gloves and goggles should be worn to prevent contact with the skin and eyes. Additionally, ingestion of this compound should be avoided, as it may cause gastrointestinal irritation and other harmful effects.
Hazard statements for 2-Chloro-1,4-naphthoquinone include “Causes skin and eye irritation” and “May cause respiratory irritation.” These statements highlight the potential risks associated with exposure to this compound and emphasize the importance of taking necessary precautions to prevent contact with the skin, eyes, and respiratory system. Individuals working with 2-Chloro-1,4-naphthoquinone should be aware of these hazards and follow appropriate safety protocols to minimize the risk of exposure.
Precautionary statements for 2-Chloro-1,4-naphthoquinone include “Avoid breathing dust/fume/gas/mist/vapors/spray” and “Wear protective gloves/protective clothing/eye protection/face protection.” These statements provide guidance on how to safely handle and use this compound to reduce the risk of harmful effects. It is important to follow these precautions when working with 2-Chloro-1,4-naphthoquinone to ensure the health and safety of individuals handling the compound.
🔬 Potential Research Directions
One potential research direction for 2-Chloro-1,4-naphthoquinone is to investigate its potential as a therapeutic agent in the treatment of various diseases. Studies could focus on its anti-inflammatory, anti-cancer, or antimicrobial properties and explore its potential mechanisms of action.
Another potential avenue for research on 2-Chloro-1,4-naphthoquinone is to study its environmental fate and toxicity. Research could explore its persistence in the environment, potential effects on non-target organisms, and ways to mitigate any harmful impacts. This could contribute valuable information to the scientific community regarding the potential risks associated with the compound.
🧪 Related Compounds
One compound that bears similarity to 2-Chloro-1,4-naphthoquinone in terms of molecular structure is 2-Bromo-1,4-naphthoquinone. This compound shares the naphthoquinone backbone and substitution at the second position, albeit with a bromine atom instead of a chlorine atom. Both compounds exhibit similar reactivity and chemical properties due to their structural resemblance.
Another compound that can be considered akin to 2-Chloro-1,4-naphthoquinone is 2-Iodo-1,4-naphthoquinone. Like the previous example, this compound contains the same naphthoquinone core and substitution pattern at the second position, but with an iodine atom instead of a chlorine atom. The presence of the halogen substituent at this location imparts similar characteristics to both compounds in terms of reactivity and stability.
