1,4-Cyclohexanedione, a chemical compound commonly utilized in the production of pharmaceuticals, plastics, and dyes, holds significant relevance to everyday life due to its versatile applications in various industries. This compound’s reactivity and structural properties make it a valuable building block for synthesizing an array of products that impact consumers’ daily experiences, ranging from medication formulations to household items. As a key ingredient in the creation of numerous essential goods, 1,4-Cyclohexanedione plays a crucial role in shaping the fabric of modern society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1,4-Cyclohexanedione, also known as p-CHD, has various commercial and industrial applications. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Additionally, it is utilized in the manufacturing of dyes and pigments due to its ability to react with a variety of functional groups.
In the realm of drug and medication applications, 1,4-Cyclohexanedione plays a crucial role as a precursor in the synthesis of pharmaceutical compounds. It is used as an intermediate in the production of drugs such as antihistamines, antifungal agents, and anti-inflammatory medications. Its versatility and reactivity make it a valuable component in the pharmaceutical industry.
Furthermore, 1,4-Cyclohexanedione has found its way into the field of medicinal chemistry, where it is used to develop novel therapeutic agents. Its unique structure and properties make it an attractive starting material for researchers looking to create new drugs with specific biological activities. This compound continues to be an essential building block in the discovery and development of pharmaceuticals with potential medical benefits.
⚗️ Chemical & Physical Properties
1,4-Cyclohexanedione appears as a white crystalline solid with a characteristic odor. The odor is often described as aromatic and slightly sweet.
The molar mass of 1,4-Cyclohexanedione is 112.15 g/mol, with a density of 1.284 g/cm³. Compared to common household items, the molar mass of 1,4-Cyclohexanedione is higher than that of water (18.015 g/mol) and slightly lower than that of sucrose (342.3 g/mol).
1,4-Cyclohexanedione has a melting point of 102-104°C and a boiling point of 255-256°C. These values are higher than the melting point and boiling point of water (0°C and 100°C, respectively), but lower than the melting point and boiling point of common cooking oils such as olive oil.
1,4-Cyclohexanedione is sparingly soluble in water, forming a clear solution. It has a low viscosity and flows easily. In comparison, 1,4-Cyclohexanedione is less soluble in water than salt, sugar, and vinegar, and exhibits lower viscosity than honey or syrup.
🏭 Production & Procurement
1,4-Cyclohexanedione, also known as 1,4-diketocyclohexane, is primarily produced through the oxidation of cyclohexanone with oxidizing agents such as hydrogen peroxide or chromic acid. This reaction typically takes place under acidic conditions to ensure the formation of the desired product. The resulting 1,4-Cyclohexanedione can then be purified through various methods such as recrystallization or column chromatography.
When it comes to the procurement and transportation of 1,4-Cyclohexanedione, the compound is commercially available from chemical suppliers in both liquid and solid form. The solid form is typically supplied as a white crystalline powder, while the liquid form is a colorless to pale yellow liquid. Due to its relatively stable nature, 1,4-Cyclohexanedione can be transported and stored under standard laboratory conditions without any special precautions.
In laboratories and industrial settings, 1,4-Cyclohexanedione is commonly stored in tightly sealed containers away from sources of heat, light, and moisture. Proper labeling of the containers with relevant safety information is essential to ensure safe handling and storage. Transportation of 1,4-Cyclohexanedione should be done in compliance with regulations governing the shipment of hazardous chemicals to prevent any accidents or spills during transit.
⚠️ Safety Considerations
Safety considerations for 1,4-Cyclohexanedione include proper handling and storage to prevent accidental exposure. It should be kept in a well-ventilated area, away from sources of ignition, and stored in a tightly closed container. Personal protective equipment, such as gloves and goggles, should be worn when handling this compound to prevent skin contact or inhalation of vapors.
In terms of pharmacology, 1,4-Cyclohexanedione is a chemical compound that is primarily used as a precursor in the synthesis of pharmaceuticals and agrochemicals. It is known for its ability to undergo various chemical reactions, leading to the formation of diverse organic compounds. However, its pharmacological properties, including any potential therapeutic effects or toxicological profiles, have not been extensively studied.
The hazard statements for 1,4-Cyclohexanedione include irritant to eyes, skin, and respiratory system. Prolonged or repeated exposure may cause skin sensitization or allergic reactions. It may also be harmful if swallowed or inhaled, leading to respiratory irritation or other adverse health effects. Proper precautions should be taken to minimize the risk of exposure and potential harm to individuals handling this compound.
Precautionary statements for 1,4-Cyclohexanedione include avoiding direct contact with the compound and using appropriate protective equipment such as gloves, goggles, and respiratory protection. In case of skin contact, affected areas should be immediately washed with soap and water. If inhaled, affected individuals should be moved to an area with fresh air. In case of ingestion, medical attention should be sought immediately, and the individual should not induce vomiting unless instructed by a medical professional.
🔬 Potential Research Directions
One potential research direction for 1,4-Cyclohexanedione is the investigation of its reactivity in various chemical reactions. By exploring how this compound participates in reactions with different types of functional groups, researchers can gain insights into its potential applications in organic synthesis.
Another area of interest is the study of the biological activity of 1,4-Cyclohexanedione and its derivatives. This compound has been shown to exhibit antimicrobial and antitumor properties, making it a promising candidate for the development of new pharmaceuticals. Further research in this area could lead to the discovery of novel drugs with improved efficacy and reduced side effects.
Additionally, exploring the structural properties of 1,4-Cyclohexanedione could provide valuable information for the design of new materials with specific physical and chemical properties. By studying the crystal structures and supramolecular assemblies of this compound, researchers can identify potential applications in areas such as materials science, nanotechnology, and drug delivery systems.
🧪 Related Compounds
One similar compound to 1,4-Cyclohexanedione based on molecular structure is 1,2-Cyclohexanedione. This compound has a similar cyclic structure with two carbonyl groups located at adjacent carbons. 1,2-Cyclohexanedione is commonly used in organic synthesis and can undergo various reactions to form different compounds.
Another similar compound to 1,4-Cyclohexanedione is 1,3-Cyclohexanedione. This compound also contains a cyclic structure with two carbonyl groups located at carbons that are one carbon apart. 1,3-Cyclohexanedione is known for its reactivity in organic reactions and can participate in various chemical transformations to yield different products.
A related compound to 1,4-Cyclohexanedione is 1,4-Cyclohexanedione ethylene acetal. This compound is a cyclic acetal derived from 1,4-Cyclohexanedione and ethylene glycol. It contains a cyclic structure with two oxygen atoms attached to the carbon atoms of the cyclohexane ring. 1,4-Cyclohexanedione ethylene acetal is used in organic synthesis as a protecting group for carbonyl compounds.
