9H-Fluoren-9-ol, a chemical compound commonly used in the production of various pharmaceuticals, plastics, and organic light-emitting diodes, holds significant relevance to everyday life. Its applications extend beyond industrial settings to impact consumer products, medical treatments, and technological advancements. As a versatile building block in the creation of diverse materials, 9H-Fluoren-9-ol plays a crucial role in enhancing the quality and functionality of numerous goods and services that individuals interact with regularly.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
9H-Fluoren-9-ol, commonly known as fluorenol, has various commercial and industrial applications. It is often used as a precursor in the synthesis of other organic compounds, particularly in the pharmaceutical and agrochemical industries. Additionally, fluorenol is utilized in the production of optical brighteners and dyes due to its fluorescent properties.
In terms of drug and medication applications, fluorenol has been studied for its potential pharmacological properties. Some research suggests that fluorenol may have neuroprotective effects, making it a candidate for the development of drugs to treat neurodegenerative disorders such as Alzheimer’s disease. However, further investigation is needed to fully understand the medicinal potential of fluorenol and its derivatives in the field of drug development.
⚗️ Chemical & Physical Properties
9H-Fluoren-9-ol appears as a white crystalline solid with no distinct odor. The compound is often described as having a slightly sweet smell.
The molar mass of 9H-Fluoren-9-ol is approximately 180.21 g/mol, and its density is around 1.19 g/cm³. Compared to common food items, such as table salt (molar mass of 58.44 g/mol, density of 2.16 g/cm³), 9H-Fluoren-9-ol has a higher molar mass but lower density.
9H-Fluoren-9-ol has a melting point of 161-165°C and a boiling point of 377°C. These values are higher compared to common food items like butter (melting point of 32-35°C, boiling point of 220°C), indicating a higher resistance to heat.
9H-Fluoren-9-ol is sparingly soluble in water and has a low viscosity. This contrasts with common food items such as sugar (high solubility in water) and honey (high viscosity), showing differences in solubility and viscosity between the compound and typical food products.
🏭 Production & Procurement
9H-Fluoren-9-ol, a key intermediate in the synthesis of pharmaceuticals and organic compounds, is typically produced through the Friedel-Crafts acylation reaction using fluorene and acetyl chloride. This reaction yields the desired 9H-Fluoren-9-ol product, which can then be purified through methods such as recrystallization or column chromatography.
Once produced, 9H-Fluoren-9-ol can be procured from chemical suppliers specializing in fine chemicals and intermediates. It is commonly available in both bulk quantities and smaller research-grade quantities. The compound is typically shipped in glass bottles or containers that are securely sealed to prevent any spillage or contamination during transport.
In order to transport 9H-Fluoren-9-ol safely, proper labeling of the container is crucial to ensure compliance with transportation regulations regarding hazardous chemicals. It is recommended to adhere to guidelines set forth by regulatory agencies such as the Department of Transportation (DOT) to ensure the safe and secure transport of the compound from the production facility to the end user.
⚠️ Safety Considerations
Safety considerations for handling 9H-Fluoren-9-ol should include proper ventilation in the working area to prevent inhalation of its vapors. Personal protective equipment such as gloves, goggles, and lab coats should be worn to minimize skin contact and eye irritation. In case of accidental ingestion, seek medical attention immediately and do not induce vomiting.
Hazard statements for 9H-Fluoren-9-ol may include “Causes skin irritation” due to its potential to irritate the skin upon contact. It may also be labeled as “Harmful if swallowed” as ingestion can lead to adverse health effects. Additionally, it may be classified as “Causes serious eye irritation” due to its irritating effects on the eyes.
Precautionary statements for handling 9H-Fluoren-9-ol should include avoiding prolonged exposure to the substance and keeping it away from heat or flames. Store it in a cool, dry place away from incompatible materials and sources of ignition. In case of skin contact, wash with plenty of soap and water, and in case of eye contact, rinse cautiously with water for several minutes while removing contact lenses.
🔬 Potential Research Directions
Research on 9H-Fluoren-9-ol could focus on its potential as a building block for new organic compounds with medicinal or material applications. Exploration of its reactivity towards various functional groups could lead to the development of novel synthetic methodologies.
Furthermore, investigations into the photophysical properties of 9H-Fluoren-9-ol, such as its absorption and emission spectra, could provide valuable insights for applications in optoelectronic devices. Studies on its stability and degradation pathways under different conditions could also contribute to its potential uses in industry.
Additionally, research on the toxicological profile of 9H-Fluoren-9-ol and its metabolites is essential for evaluating its safety for human and environmental exposure. Investigations into its environmental fate and potential ecological impacts could also provide important information for risk assessment and regulatory purposes.
🧪 Related Compounds
One similar compound to 9H-Fluoren-9-ol is 9H-Fluoren-9-one, which differs only by the functional group attached to the carbon atom at position 9. In 9H-Fluoren-9-one, an oxygen atom is bonded to this carbon instead of a hydroxyl group, resulting in a ketone rather than an alcohol. This slight modification in functional group can have significant implications for the compound’s chemical properties and reactivity.
Another similar compound to 9H-Fluoren-9-ol is 9,9-Dimethyl-9H-fluorene, which features two methyl groups attached to the carbon atoms at positions 9 and 9. This substitution of hydrogen atoms with methyl groups can lead to different physical and chemical properties compared to 9H-Fluoren-9-ol. The presence of bulky methyl groups can affect the compound’s solubility, melting point, and reactivity.
A third similar compound to 9H-Fluoren-9-ol is 9H-Fluorene, which lacks the hydroxyl group at position 9 found in 9H-Fluoren-9-ol. Instead, 9H-Fluorene contains two benzene rings fused together but lacks functional groups typically associated with alcohols or ketones. Despite the similarity in structure, the absence of a hydroxyl group can result in different chemical behaviors and applications for 9H-Fluorene compared to 9H-Fluoren-9-ol.
