9,13-Di-cis-retinoic acid, a form of retinoic acid derived from vitamin A, plays a crucial role in regulating various biological processes in the human body. Specifically, it is involved in cell growth, differentiation, and development. In everyday life, this compound is essential for maintaining healthy skin, vision, and immune function. Additionally, it has been studied for its potential therapeutic effects in treating certain skin disorders, such as acne and psoriasis, as well as certain types of cancer. Despite its importance, further research is needed to fully understand the impact of 9,13-Di-cis-retinoic acid on human health and disease.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
9,13-Di-cis-retinoic acid, commonly known as a retinoid, has found commercial and industrial applications predominantly in the field of pharmacology and cosmetics. This compound is utilized in the formulation of certain skincare products, primarily for its purported ability to promote healthy skin cell turnover and improve overall skin texture.
In addition to its cosmetic applications, 9,13-Di-cis-retinoic acid has been studied for its potential industrial uses. It has been explored as a possible ingredient in dietary supplements and functional foods, with researchers investigating its potential benefits in promoting eye health, regulating gene expression, and supporting overall immune function.
When it comes to drug and medication applications, 9,13-Di-cis-retinoic acid has shown promise in the treatment of certain dermatological conditions, such as acne and psoriasis. This compound is also being researched for its potential anti-cancer properties, with studies suggesting that it may have a role in inhibiting tumor growth and promoting cancer cell differentiation.
⚗️ Chemical & Physical Properties
9,13-Di-cis-retinoic acid is a white crystalline solid with no distinct odor. It is commonly known for its vitamin A-like properties and is a crucial component in various biological processes.
The molar mass of 9,13-Di-cis-retinoic acid is approximately 300.44 g/mol, with a density of around 1.12 g/cm³. This places it in the same range as common food items such as sucrose and glucose in terms of molar mass and density.
9,13-Di-cis-retinoic acid has a melting point of around 180-182°C and a boiling point of approximately 344-346°C. Compared to common food items like butter and chocolate, it has a higher melting point and boiling point.
In terms of solubility in water, 9,13-Di-cis-retinoic acid is sparingly soluble, but exhibits high viscosity. This contrasts with common food items like salt and sugar, which are highly soluble in water and have lower viscosity levels.
🏭 Production & Procurement
9,13-Di-cis-retinoic acid is produced through a complex chemical synthesis process involving the manipulation of retinol, a derivative of vitamin A. This process requires specialized equipment and expertise due to the delicate nature of the molecule and the need for precise control of reaction conditions.
Once produced, 9,13-Di-cis-retinoic acid can be procured from chemical suppliers who specialize in the synthesis and distribution of rare and specialty compounds. The compound is typically packaged in glass vials or ampules to protect it from light and air, as it is sensitive to degradation when exposed to these elements. Special care must be taken during transportation to ensure the stability and integrity of the compound.
Transportation of 9,13-Di-cis-retinoic acid is usually done under controlled conditions, such as refrigeration or inert gas atmosphere, to prevent degradation during transit. Due to its sensitivity to light and air, the compound is often shipped in tinted or opaque containers to minimize exposure. Proper documentation and labeling are essential to ensure safe handling and regulatory compliance during transport.
⚠️ Safety Considerations
Safety considerations for 9,13-Di-cis-retinoic acid must be taken into account due to its potential hazards. When handling this chemical, it is important to wear appropriate personal protective equipment, such as gloves and safety goggles, to prevent skin and eye irritation. It is also crucial to work in a well-ventilated area to avoid inhaling any potentially harmful vapors.
In addition, 9,13-Di-cis-retinoic acid should be stored in a tightly sealed container in a cool, dry place away from incompatible substances. Proper labeling of the container with hazard symbols and information about the chemical is essential to prevent any accidents or confusion. Spills should be cleaned up immediately using appropriate absorbent materials and individuals should wash their hands thoroughly after handling this compound.
The hazard statements for 9,13-Di-cis-retinoic acid include causing skin irritation, serious eye damage, and respiratory irritation. Prolonged or repeated exposure to this substance may result in adverse health effects. It is important to follow proper safety protocols when working with this chemical to minimize the risk of harm to oneself or others.
Precautionary statements for 9,13-Di-cis-retinoic acid include wearing protective gloves, eye protection, and clothing to avoid skin contact and eye exposure. It is recommended to work in a well-ventilated area to prevent inhalation of vapors and to wash hands and any contaminated clothing thoroughly after handling this compound. In case of skin irritation, it is advised to seek medical attention and remove any contaminated clothing.
🔬 Potential Research Directions
One potential research direction for 9,13-Di-cis-retinoic acid involves studying its biological activity and potential therapeutic applications in the field of cancer research.
Furthermore, investigations into the molecular mechanisms of action of 9,13-Di-cis-retinoic acid could provide insights into its mode of action and potential targets for drug development.
Additionally, exploring the pharmacokinetics and pharmacodynamics of 9,13-Di-cis-retinoic acid could enhance our understanding of its efficacy and safety profile for clinical use.
Moreover, investigating the potential synergistic effects of 9,13-Di-cis-retinoic acid with other pharmacological agents may lead to the development of novel combination therapies for various diseases.
🧪 Related Compounds
One similar compound to 9,13-Di-cis-retinoic acid is All-trans-retinoic acid. This compound is a metabolite of Vitamin A and plays a crucial role in regulating cell growth and differentiation. All-trans-retinoic acid is known for its ability to induce cell differentiation and has been used in the treatment of various cancers, such as acute promyelocytic leukemia.
Another compound similar to 9,13-Di-cis-retinoic acid is 9-cis-retinoic acid. This compound is an agonist of the retinoic acid receptors and is involved in regulating gene expression. 9-cis-retinoic acid has been studied for its potential therapeutic effects in diseases such as skin disorders and various cancers.
A third compound similar to 9,13-Di-cis-retinoic acid is 13-cis-retinoic acid. This compound is an isomer of All-trans-retinoic acid and is also known for its role in regulating cell differentiation and proliferation. 13-cis-retinoic acid has been used in the treatment of acne and certain types of cancer due to its ability to modulate gene expression.
