9,12-Octadecadienoic Acid, also known as linoleic acid, plays a crucial role in human health as an essential fatty acid that must be obtained through the diet. It is a key component of cell membranes and is necessary for the proper functioning of the immune system, brain, and nervous system. Additionally, linoleic acid has been shown to have anti-inflammatory properties and is important for maintaining healthy skin and hair. In everyday life, consuming foods rich in linoleic acid, such as nuts, seeds, and vegetable oils, can help promote overall well-being and support optimal health.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
9,12-Octadecadienoic Acid, also known as linoleic acid, is a common polyunsaturated omega-6 fatty acid found in many plant and animal fats. In commercial and industrial applications, it is widely used as a drying oil in paints, varnishes, and other coatings due to its ability to polymerize and form a protective film when exposed to air. Additionally, it is utilized as an emulsifier in the production of soaps, detergents, and cosmetics, where it helps to stabilize mixtures and prevent separation.
In the field of drug and medication applications, 9,12-Octadecadienoic Acid plays a crucial role in the human diet as an essential fatty acid that the body cannot synthesize on its own. It is known for its anti-inflammatory properties and its ability to support the health of the skin, hair, and nails. Additionally, linoleic acid is used in pharmaceutical formulations to improve drug solubility and bioavailability, particularly in lipid-based formulations such as soft gel capsules and topical creams designed to deliver active ingredients into the skin.
⚗️ Chemical & Physical Properties
9,12-Octadecadienoic Acid, also known as linoleic acid, appears as a colorless to pale yellow liquid with a faint odor. It is commonly found in various vegetable oils such as sunflower, safflower, and corn oil.
With a molar mass of approximately 280.45 g/mol and a density of about 0.902 g/cm3, 9,12-Octadecadienoic Acid is relatively lighter compared to common food items such as sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm3) and salt (molar mass: 58.44 g/mol, density: 2.165 g/cm3).
The melting point of 9,12-Octadecadienoic Acid is around -5°C, while the boiling point is approximately 221°C. In comparison, common food items like butter (melting point: 32-35°C, boiling point: 150-250°C) and olive oil (melting point: -6 to -3°C, boiling point: 200°C) exhibit different melting and boiling points.
9,12-Octadecadienoic Acid is practically insoluble in water but soluble in organic solvents like ethanol and acetone. It possesses a relatively low viscosity compared to common food items like honey and molasses, making it easier to handle and mix in formulations.
🏭 Production & Procurement
In the production of 9,12-Octadecadienoic Acid, commonly known as linoleic acid, it is typically extracted from plant sources such as nuts, seeds, and vegetable oils. The process involves crushing or pressing the plant material to obtain the oil containing the acid, which is then further processed through methods like distillation or solvent extraction to isolate and purify the compound.
Once 9,12-Octadecadienoic Acid has been produced, it can be procured through various methods such as bulk purchasing from manufacturers or suppliers specializing in fatty acids. The acid is usually transported in liquid form, either in drums or tanks, to ensure its stability during shipping. It is important to protect the acid from exposure to air, light, and high temperatures to prevent degradation.
In addition to traditional procurement methods, 9,12-Octadecadienoic Acid can also be obtained from online retailers or chemical distributors who offer the compound for sale to individual consumers or small businesses. Depending on the quantity needed, the acid can be shipped in smaller containers such as bottles or vials for ease of handling and storage. It is crucial to follow proper handling and storage guidelines to maintain the quality and stability of the acid.
⚠️ Safety Considerations
Safety considerations for 9,12-Octadecadienoic Acid, commonly known as linoleic acid, should be taken into account due to its potential hazards. This compound may cause skin irritation and serious eye damage upon contact. It is also harmful if swallowed and may lead to respiratory irritation if inhaled. Therefore, appropriate personal protective equipment, such as gloves and safety goggles, should be worn when handling this substance to minimize the risk of exposure.
Hazard statements for 9,12-Octadecadienoic Acid include “Causes skin irritation,” “Causes serious eye damage,” “Harmful if swallowed,” and “May cause respiratory irritation.” These statements indicate the potential risks associated with this compound and emphasize the importance of proper handling and protective measures to prevent adverse effects. It is crucial to follow safety guidelines and protocols when working with 9,12-Octadecadienoic Acid to ensure the wellbeing of individuals and minimize the likelihood of accidents or injuries.
Precautionary statements for 9,12-Octadecadienoic Acid advise the use of appropriate personal protective equipment, such as gloves and safety goggles, to protect against skin and eye irritation. It is also recommended to avoid breathing in vapors or mists of this compound and to work in a well-ventilated area to minimize the risk of respiratory irritation. In case of skin contact, the affected area should be washed with plenty of water, and in case of eye contact, immediate medical attention is required. Additionally, 9,12-Octadecadienoic Acid should be stored in a tightly closed container away from heat sources and incompatible materials to prevent accidents or spills.
🔬 Potential Research Directions
Research on 9,12-Octadecadienoic Acid, commonly known as linoleic acid, may explore its role in human health and disease. This fatty acid is considered essential for the body, as it cannot be synthesized and must be obtained through dietary sources.
Studies may investigate the effects of dietary intake of linoleic acid on inflammation, cardiovascular health, and metabolic disorders. Researchers may explore the potential benefits of linoleic acid supplementation in preventing and managing chronic diseases such as diabetes and obesity.
Further research could focus on the bioavailability and metabolism of linoleic acid in the body. Understanding how the body absorbs, distributes, and utilizes this fatty acid may provide valuable insights into its physiological impacts and potential therapeutic applications.
🧪 Related Compounds
One similar compound to 9,12-Octadecadienoic Acid is 9,12-Octadecadienoyl chloride. This compound has a similar structure to 9,12-Octadecadienoic Acid, with a long hydrocarbon chain and a double bond at the 9th and 12th positions. Octadecadienoyl chloride is commonly used in organic synthesis as an intermediate for the preparation of various compounds.
Another similar compound to 9,12-Octadecadienoic Acid is Methyl 9-cis,12-cis-octadecadienoate. This compound has the same double bond positions at the 9th and 12th carbons as 9,12-Octadecadienoic Acid, but with a methyl ester group instead of a carboxylic acid group. Methyl octadecadienoate is often used as a flavoring agent in the food industry due to its fruity aroma.
Additionally, a related compound to 9,12-Octadecadienoic Acid is 9,12,15-Octadecatrienoic Acid. This compound has an additional double bond at the 15th position compared to 9,12-Octadecadienoic Acid, leading to a different chemical reactivity and properties. 9,12,15-Octadecatrienoic acid is also known as alpha-linolenic acid and is an essential fatty acid found in various plant oils.
