9-Hydroxy-10,12-octadecadienoic acid is a compound that is biologically derived from certain dietary sources and has been shown to have potential health benefits. It is a type of unsaturated fatty acid that is commonly found in plant-based oils like linseed, perilla, and hemp. Studies have suggested that this acid may have anti-inflammatory and antioxidant properties, which could be beneficial for maintaining good health and potentially reducing the risk of certain chronic diseases. While more research is needed to fully understand its effects, the relevance of 9-Hydroxy-10,12-octadecadienoic acid lies in its potential impact on human health and well-being, making it a topic of interest in the field of nutrition and health science.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
9-Hydroxy-10,12-octadecadienoic acid, commonly known as 9-HODE, has found various commercial and industrial applications due to its unique properties. It is often used as a key ingredient in skincare products, where its anti-inflammatory and antioxidant properties help in reducing skin damage caused by free radicals. In addition, 9-HODE is also utilized in the food industry as a natural preservative due to its ability to inhibit the growth of harmful microorganisms.
In the field of drug and medication applications, 9-Hydroxy-10,12-octadecadienoic acid has shown promise as a potential therapeutic agent for various inflammatory conditions. Its anti-inflammatory properties make it a valuable compound in the treatment of diseases such as arthritis, asthma, and inflammatory bowel disease. Researchers are also exploring the potential of 9-HODE in cancer treatment, as studies have shown its ability to inhibit the growth and spread of cancer cells in laboratory settings.
Moreover, 9-Hydroxy-10,12-octadecadienoic acid has shown potential in the development of novel drug delivery systems. Its ability to modulate the immune response and improve drug solubility makes it an attractive candidate for targeted drug delivery. In addition, 9-HODE has been investigated for its role in promoting wound healing and tissue regeneration, offering potential applications in the field of regenerative medicine.
⚗️ Chemical & Physical Properties
9-Hydroxy-10,12-octadecadienoic acid, also known as 9-HOD, is a white crystalline powder with no discernible odor. It is a fatty acid derived from linoleic acid, commonly found in plant oils.
The molar mass of 9-HOD is approximately 294.46 g/mol, with a density of about 1.0 g/cm3. This places it in the range typical of common food items such as vegetable oils, which have similar molar masses and densities.
9-HOD has a melting point of around 51-53°C and a boiling point of approximately 280-285°C. These values are slightly higher than those of common food items like butter or olive oil, which have lower melting and boiling points.
9-HOD is sparingly soluble in water, but highly soluble in organic solvents. It exhibits a moderate viscosity, comparable to that of vegetable oils but lower than that of honey or molasses.
🏭 Production & Procurement
9-Hydroxy-10,12-octadecadienoic acid, also known as 9-HODE, is typically produced through the oxidation of linoleic acid. This process involves the action of enzymes such as lipoxygenases or the use of chemical reagents to convert linoleic acid into 9-HODE.
In order to procure 9-Hydroxy-10,12-octadecadienoic acid for research or industrial purposes, it can be obtained from chemical suppliers specializing in lipid products. The compound may be available in various forms, including pure forms for laboratory research or as part of mixtures for specific applications.
For transportation purposes, 9-Hydroxy-10,12-octadecadienoic acid may be shipped in sealed containers to prevent degradation or contamination. It is essential to handle the compound with care to ensure its stability during transit. Proper labeling and documentation are necessary to comply with regulatory requirements for the transportation of chemical compounds.
⚠️ Safety Considerations
Safety considerations for 9-Hydroxy-10,12-octadecadienoic acid, also known as 9-HODE, should be carefully considered due to its potential hazards. This compound is a fatty acid hydroperoxide that can pose risks to both human health and the environment. When handling 9-HODE, it is important to wear appropriate personal protective equipment, such as gloves and goggles, to prevent skin contact or inhalation of the substance. Additionally, measures should be taken to minimize the release of 9-HODE into the environment, as it can have toxic effects on aquatic organisms and may contribute to air pollution.
Hazard statements for 9-Hydroxy-10,12-octadecadienoic acid include its potential to cause skin irritation and serious eye damage. This compound may also be harmful if swallowed or inhaled, leading to respiratory irritation or other adverse effects. In addition, 9-HODE is classified as a hazardous substance that can have long-term negative impacts on human health and the environment. Therefore, precautions should be taken to minimize exposure to this compound and prevent any potential accidents or incidents involving its use.
Precautionary statements for 9-Hydroxy-10,12-octadecadienoic acid emphasize the importance of using proper protective measures when working with this compound. It is recommended to wear suitable gloves, eye protection, and clothing to minimize the risk of skin contact or inhalation. In addition, individuals handling 9-HODE should work in a well-ventilated area to reduce exposure to potentially harmful vapors. Proper storage and disposal practices should also be followed to prevent contamination of the surrounding environment and ensure the safety of personnel involved in handling this compound.
🔬 Potential Research Directions
Research on 9-Hydroxy-10,12-octadecadienoic acid could focus on its biological activities, including its potential anti-inflammatory, anti-cancer, and antioxidant properties. Moreover, studies could investigate its potential role in regulating lipid metabolism and its impact on various cellular signaling pathways.
Future research directions may involve elucidating the molecular mechanisms underlying the biological effects of 9-Hydroxy-10,12-octadecadienoic acid. This could include exploring its interaction with specific cellular targets, its modulation of gene expression, or its influence on enzymatic activity within the cell.
Furthermore, investigations could delve into the pharmacokinetics and pharmacodynamics of 9-Hydroxy-10,12-octadecadienoic acid to better understand its bioavailability, metabolism, and distribution in different tissues. This could shed light on its potential as a therapeutic agent for various diseases or as a dietary supplement for health promotion.
🧪 Related Compounds
One similar compound to 9-Hydroxy-10,12-octadecadienoic acid based upon molecular structure is 9-Hydroxy-10-octadecadienoic acid. This compound also contains a hydroxyl group at the 9th carbon and a double bond at the 10th and 12th carbons. The only difference is the absence of the hydroxyl group on the 12th carbon.
Another related compound is 13-Hydroxy-9,10-octadecadienoic acid. In this compound, the hydroxyl group is located at the 13th carbon, while the double bonds are at the 9th and 10th carbons. This variation in the position of the hydroxyl group results in a slight difference in the chemical properties of the compound compared to 9-Hydroxy-10,12-octadecadienoic acid.
Additionally, 9-Hydroxy-8,10-octadecadienoic acid is another compound with a similar structure. In this compound, the hydroxyl group is situated at the 9th carbon, while the double bonds are present at the 8th and 10th carbons. This slight rearrangement of the double bonds alters the physical and chemical properties of the compound in comparison to 9-Hydroxy-10,12-octadecadienoic acid.
