8-Hydroxyquinoline N-oxide, a chemical compound commonly used in pharmaceuticals, research, and industrial applications, plays an important role in everyday life. This compound has been utilized in the development of medications, such as antimalarial and antibacterial drugs, as well as in the production of dyes and metal complexes. Additionally, 8-Hydroxyquinoline N-oxide has shown promise in research related to neurodegenerative diseases, making it a valuable tool in the pursuit of medical advancements. Its diverse applications highlight the significance of this compound in various aspects of daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
8-Hydroxyquinoline N-oxide, commonly referred to as oxine or oxyquinoline, has several commercial and industrial applications. It is commonly used as a chelating agent in industry, particularly in the production of metal ion indicators and metal plating processes. It is also utilized as a corrosion inhibitor in various industrial applications due to its ability to complex with metal ions and form stable complexes.
In the field of drug and medication applications, 8-Hydroxyquinoline N-oxide has been studied for its potential antimicrobial properties. Some research suggests that it may be effective against certain types of bacteria and fungi, making it a candidate for use in disinfectants and antiseptic formulations. Additionally, it has shown promise in the treatment of certain skin conditions due to its antifungal and antibacterial properties.
Overall, 8-Hydroxyquinoline N-oxide’s versatility makes it a valuable compound in a variety of commercial, industrial, and medical applications. Its ability to chelate metal ions, inhibit corrosion, and potentially act as an antimicrobial agent highlights its importance in various fields of study and production. Further research and development may uncover even more uses for this compound in the future.
⚗️ Chemical & Physical Properties
8-Hydroxyquinoline N-oxide, a white crystalline solid, possesses a faint odor. When handled, one may notice a subtle chemical smell emanating from the compound.
With a molar mass of 171.16 g/mol and a density of 1.35 g/cm³, 8-Hydroxyquinoline N-oxide has similar properties to many common food items. For instance, sugar has a molar mass of 342.30 g/mol and a density of 1.59 g/cm³.
8-Hydroxyquinoline N-oxide has a melting point of approximately 235-237°C and a boiling point of approximately 350-360°C. These values differ significantly from those of common food items, such as chocolate, which has a melting point around 30-32°C and a boiling point around 160°C.
This compound is sparingly soluble in water and exhibits low viscosity. Compared to common food items like salt, which is highly soluble in water, 8-Hydroxyquinoline N-oxide demonstrates relatively poor solubility and lower viscosity.
🏭 Production & Procurement
8-Hydroxyquinoline N-oxide, commonly referred to as 8-HQNO, is typically produced through a multistep synthesis process. The starting material for the production of 8-HQNO is 8-hydroxyquinoline, which undergoes oxidation to form the desired compound. Various chemical reactions are employed to convert 8-hydroxyquinoline into 8-HQNO in a controlled laboratory setting.
In order to procure 8-Hydroxyquinoline N-oxide, it is important to have access to specialized chemical suppliers or manufacturers. Due to the complex synthesis process involved in the production of 8-HQNO, it is not typically available for purchase in general chemical supply stores. Once procured, 8-Hydroxyquinoline N-oxide can be transported in sealed containers to prevent any potential contamination or degradation during transit.
Transportation of 8-Hydroxyquinoline N-oxide should adhere to strict guidelines regarding chemical handling and safety practices. The compound should be securely packaged to prevent leakage or breakage during transit. It is advisable to utilize a reputable transportation company that specializes in the safe transport of chemical substances to ensure the integrity of the product.
⚠️ Safety Considerations
Safety considerations for 8-Hydroxyquinoline N-oxide must be taken into account due to its potential hazards. This substance is harmful if ingested, inhaled, or in contact with skin. It may cause irritation to the respiratory tract, skin, and eyes. In case of exposure, it is important to seek medical attention immediately.
In addition, 8-Hydroxyquinoline N-oxide may be harmful to aquatic organisms, posing a risk to the environment if not properly handled. It is important to prevent any release of this substance into the environment and to dispose of it in accordance with local regulations. Proper personal protective equipment should be worn when handling 8-Hydroxyquinoline N-oxide to minimize the risk of exposure.
Hazard statements for 8-Hydroxyquinoline N-oxide include “Causes skin irritation,” “Causes serious eye irritation,” and “Toxic to aquatic life with long lasting effects.” These statements indicate the potential dangers associated with this substance and emphasize the need for caution when handling it. It is important to follow safety protocols and guidelines to minimize the risk of harm to individuals and the environment.
Precautionary statements for 8-Hydroxyquinoline N-oxide include “Wear protective gloves/eye protection/face protection,” “IF ON SKIN: Wash with plenty of water,” and “Dispose of contents/container in accordance with local/regional/national/international regulations.” These statements provide important guidelines for safe handling and disposal of this substance. It is crucial to follow these precautionary measures to mitigate the risks associated with 8-Hydroxyquinoline N-oxide and to ensure the safety of individuals and the environment.
🔬 Potential Research Directions
One potential research direction for 8-Hydroxyquinoline N-oxide is its potential use as a therapeutic agent in cancer treatment. Studies have shown that this compound exhibits antitumor activity by inducing apoptosis in cancer cells. Further research is warranted to elucidate the underlying mechanisms of its anticancer properties.
Another avenue of study could be focused on the antioxidant properties of 8-Hydroxyquinoline N-oxide. Research has indicated that this compound possesses strong antioxidant activity, which could be beneficial in reducing oxidative stress and inflammation in various disease states. Investigating its potential as a neuroprotective agent in neurological disorders may also be of interest.
Furthermore, the antimicrobial activity of 8-Hydroxyquinoline N-oxide presents a promising research area. Studies have shown that this compound exhibits antibacterial and antifungal properties, suggesting its potential as a novel antibiotic or antifungal agent. Exploration of its mechanism of action and potential applications in combating drug-resistant pathogens could be a fruitful research direction.
Additionally, the role of 8-Hydroxyquinoline N-oxide in metal chelation and ion sensing can be a fascinating research avenue. This compound has been shown to form complexes with various metal ions, which could have implications in the development of metal ion sensors or chelation therapy for metal ion overload disorders. Further investigations into its metal-binding properties and applications in metal ion detection are warranted.
🧪 Related Compounds
One similar compound to 8-Hydroxyquinoline N-oxide based upon molecular structure is 8-Hydroxyquinoline. This compound is composed of a quinoline ring structure with a hydroxyl group attached at the 8th carbon position. While lacking the N-oxide functionality, 8-Hydroxyquinoline shares a similar core structure with 8-Hydroxyquinoline N-oxide.
Another compound related to 8-Hydroxyquinoline N-oxide is Quinoline N-oxide. This compound features a quinoline ring structure with an N-oxide functional group attached at the nitrogen atom. Quinoline N-oxide differs from 8-Hydroxyquinoline N-oxide in the position of the oxygen atom within the molecule, but shares the quinoline backbone.
Additionally, Quinoline is a compound that bears structural similarity to 8-Hydroxyquinoline N-oxide. Quinoline lacks the hydroxyl and N-oxide functional groups present in 8-Hydroxyquinoline N-oxide but shares the same quinoline ring structure. Quinoline is a base compound that can undergo various modifications to result in derivatives such as 8-Hydroxyquinoline N-oxide.