5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione, a chemical compound commonly known as MPTP, has significant relevance to everyday life due to its role in Parkinson’s disease research. MPTP is a neurotoxin that can induce Parkinsonian symptoms in humans, making it a valuable tool for studying the underlying causes of the disease. By understanding how MPTP affects the brain, researchers can gain insights into potential treatments and therapies for this debilitating condition that affects millions of individuals worldwide. As such, the study of compounds like MPTP has the potential to improve the quality of life for those living with Parkinson’s disease.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
The compound 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione has various commercial and industrial applications. It is commonly used as a chemical intermediate in the synthesis of pharmaceutical compounds, agrochemicals, and dyes. The compound’s unique structure and properties make it valuable in the production of specialty chemicals and materials.
In the pharmaceutical industry, 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione is used as a key building block for the production of certain drugs and medications. It serves as a precursor in the synthesis of various pharmaceutical compounds that can be used to treat a range of medical conditions. The compound’s versatility and reactivity make it an essential component in drug discovery and development processes.
Additionally, 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione is utilized in the formulation of certain medications for therapeutic purposes. Its unique chemical properties make it an ideal candidate for inclusion in drug formulations designed to enhance the efficacy and stability of active pharmaceutical ingredients. The compound’s role in drug delivery systems and pharmaceutical formulations highlights its importance in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
The compound 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione appears as a white crystalline powder with no discernible odor. Its physical properties include a molar mass of approximately 328.3 g/mol and a density of about 1.32 g/cm³. This places it in a range of molar masses and densities similar to common household items such as table salt (NaCl) and sugar (C12H22O11).
The melting point of 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione is approximately 215-217°C, while its boiling point is around 458-462°C. These values are significantly higher than those of water and common household items, making this compound less susceptible to changes in temperature compared to substances like ice and cooking oil.
5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione is sparingly soluble in water but dissolves more readily in organic solvents. It has a low viscosity, meaning it flows easily. In comparison to common household items, this compound’s solubility in water is closer to that of oil-based paints, while its viscosity is more similar to rubbing alcohol.
🏭 Production & Procurement
5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione, a compound used in various pharmaceutical and chemical applications, is typically produced through a series of synthetic chemical reactions. The synthesis usually involves the condensation of appropriate starting materials under specific reaction conditions to yield the desired compound. This process requires a high level of expertise and precision to ensure the purity and quality of the final product.
Once 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione has been successfully produced, it can be procured through specialized chemical suppliers. These suppliers typically offer the compound in various quantities, ranging from small research-grade samples to bulk industrial quantities. The compound can be transported to customers through standardized shipping methods, such as ground or air freight, with appropriate safety measures in place to ensure compliance with regulations and to prevent any potential hazards during transit.
In addition to procuring 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione from chemical suppliers, the compound can also be synthesized in-house by research institutions or pharmaceutical companies with the necessary expertise and equipment. This allows for greater control over the production process and the ability to tailor the synthesis to specific research or manufacturing requirements. However, in-house synthesis requires a significant investment in resources and expertise to ensure the successful and efficient production of the compound.
⚠️ Safety Considerations
Safety considerations for 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione include proper handling to avoid skin contact, inhalation, or ingestion. It is essential to utilize personal protective equipment such as gloves, goggles, and a lab coat when working with this chemical. Additionally, the substance should be stored in a cool, dry, well-ventilated area away from incompatible materials to prevent accidents or reactions.
The pharmacology of 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione involves its function as an inhibitor of a specific enzyme in the body. This enzyme plays a crucial role in a metabolic pathway, and inhibiting its activity can lead to therapeutic effects in certain medical conditions. The compound is being studied for its potential use in treating various diseases and disorders, with research ongoing to understand its mechanisms of action and potential benefits.
Hazard statements for 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione include the substance being harmful if swallowed, causing skin irritation or serious eye damage upon contact. It may also be toxic to aquatic life with long-lasting effects if released into the environment. Individuals working with this compound should be aware of these hazards and take necessary precautions to prevent exposure and minimize risks to themselves and the environment.
Precautionary statements for 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione recommend wearing protective clothing, gloves, and eye protection when handling the substance. It is advised to avoid release into the environment and dispose of properly according to regulations. In case of accidental exposure, immediate medical attention is recommended, along with thorough cleaning and decontamination of the affected area. It is crucial to follow proper safety protocols and guidelines when working with this compound to ensure the well-being of individuals and the environment.
🔬 Potential Research Directions
Research on 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione, a pyrimidine derivative, may focus on understanding its potential biological activities and pharmacological properties.
One potential research direction could involve investigating the compound’s anticancer properties, as pyrimidine derivatives have been shown to exhibit anti-tumor activities through various mechanisms.
Another avenue of study may involve exploring the compound’s potential as a novel drug candidate for the treatment of neurodegenerative diseases, given the importance of pyrimidine derivatives in neuroscience research.
Further research could be conducted to elucidate the molecular targets and pathways through which 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione exerts its biological effects, in order to better understand its mechanism of action.
Additionally, future research could focus on synthesizing analogs and derivatives of the compound to optimize its pharmacological properties and enhance its potential as a therapeutic agent in various disease contexts.
🧪 Related Compounds
One similar compound to 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione based on molecular structure is 5-(4-chlorophenyl)-5-methylpyrimidine-2,4,6(1H,3H,5H)-trione. This compound shares the same pyrimidine ring structure as 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione but contains a chlorine atom on the phenyl ring instead of a phenoxy group, resulting in different characteristics and potential biological activities.
Another similar compound is 5-Methyl-5-(4-methoxy-phenyl)-pyrimidine-2,4,6-trione. This compound also contains a pyrimidine ring structure with a methyl group at the five position, but it has a methoxy group on the phenyl ring instead of a phenoxy group. The presence of the methoxy group can impart different physical and chemical properties to the compound compared to 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione.
One additional similar compound is 5-Methyl-5-(4-hydroxy-phenyl)-pyrimidine-2,4,6-trione. This compound shares the same pyrimidine ring structure with a methyl group at the five position, but it contains a hydroxyl group on the phenyl ring instead of a phenoxy group. The hydroxyl group can introduce different chemical reactivity and potential biological activities compared to 5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione.
