5-Chlorosalicylic Acid, a derivative of salicylic acid, is a compound used in various industries such as pharmaceuticals, agrochemicals, and cosmetics. In everyday life, this chemical plays a crucial role in the development of pharmaceuticals including anti-inflammatory drugs, antipyretics, and analgesics. Additionally, it is used in agrochemical products for crop protection and in cosmetics for skin care formulations. Overall, 5-Chlorosalicylic Acid contributes to improving human health, food production, and personal care products that are integral aspects of modern daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
5-Chlorosalicylic Acid, also known as 2-Hydroxy-5-chlorobenzoic acid, has various commercial and industrial applications. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. Additionally, it is utilized in the manufacturing of polymers, resins, and rubber chemicals due to its versatile chemical properties.
In terms of drug and medication applications, 5-Chlorosalicylic Acid is used as a building block in the production of anti-inflammatory drugs. Its ability to inhibit the production of prostaglandins makes it a valuable ingredient in medications that target pain and inflammation. Furthermore, it is employed in the synthesis of antifungal agents and anti-malarial drugs, showcasing its importance in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
5-Chlorosalicylic Acid is a white crystalline solid with a faint odor. It appears as fine, powdery particles that are easily soluble in water.
The molar mass of 5-Chlorosalicylic Acid is approximately 202.6 g/mol, and its density is about 1.52 g/cm³. In comparison to common food items, 5-Chlorosalicylic Acid has a higher molar mass and density.
5-Chlorosalicylic Acid has a melting point of around 238-240°C and a boiling point of approximately 530-540°C. In comparison to common food items, 5-Chlorosalicylic Acid has higher melting and boiling points.
5-Chlorosalicylic Acid is readily soluble in water and has a moderate viscosity. In comparison to common food items, 5-Chlorosalicylic Acid has higher solubility in water but similar viscosity properties.
🏭 Production & Procurement
5-Chlorosalicylic acid is typically produced through a multi-step process involving the chlorination of salicylic acid. This reaction is carried out under stringent conditions to ensure the selectivity of the desired product. The chlorinated product is further processed to yield 5-Chlorosalicylic acid.
5-Chlorosalicylic acid can be procured from specialized chemical suppliers that produce and distribute fine chemicals. It is typically available in various quantities ranging from grams to kilograms. The compound is commonly transported in sealed containers to prevent degradation or contamination during transit.
The procurement of 5-Chlorosalicylic acid may also involve importation from international suppliers in countries where it is manufactured in large quantities. Companies that require bulk quantities may establish direct relationships with manufacturers to secure a stable supply chain. In some cases, specialized chemical logistics providers may be employed to ensure safe and efficient transportation of the compound.
Storage of 5-Chlorosalicylic acid should be carried out in a cool, dry place away from sources of heat or ignition. Proper labeling and handling procedures should be adhered to in accordance with safety regulations and guidelines. The compound should be stored in airtight containers to prevent moisture absorption and degradation over time.
Upon receipt, the compound should be inspected for any signs of damage or contamination before use. Quality control measures should be implemented to ensure the purity and integrity of the product. Proper disposal methods should be followed for any unused or expired quantities of 5-Chlorosalicylic acid to minimize environmental impact.
⚠️ Safety Considerations
Safety considerations for 5-Chlorosalicylic Acid include the fact that it may cause skin and eye irritation upon contact. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when handling this compound. Additionally, it should be stored in a cool, dry place away from heat and sources of ignition to prevent the risk of fire or explosion.
Hazard statements for 5-Chlorosalicylic Acid include “Causes skin and eye irritation” and “May cause respiratory irritation.” These statements highlight the potential risks associated with exposure to this compound, emphasizing the importance of taking precautions to minimize the likelihood of harm. It is essential to handle this substance with care and to follow safety guidelines to prevent accidents and injuries.
Precautionary statements for 5-Chlorosalicylic Acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.” These statements emphasize the need for using proper protective equipment and taking prompt action in case of exposure. By following these precautions, the risk of harm from 5-Chlorosalicylic Acid can be significantly reduced.
🔬 Potential Research Directions
One potential research direction for 5-Chlorosalicylic Acid is to investigate its potential as a pharmaceutical compound for the treatment of inflammatory conditions, given its structural similarity to salicylic acid, a known anti-inflammatory agent.
Another potential research avenue is to explore its potential as a corrosion inhibitor in various industries, due to its ability to form protective layers on metal surfaces when used in coatings or solutions.
Furthermore, research could be conducted on the environmental impact of 5-Chlorosalicylic Acid, including its biodegradability and toxicity to aquatic organisms, to better understand its potential risks and benefits in various applications.
Additionally, studies could be conducted on the synthesis and purification methods of 5-Chlorosalicylic Acid to optimize its production efficiency and purity for various industrial uses.
Lastly, research on the chemical reactivity and potential applications of 5-Chlorosalicylic Acid derivatives could provide insights into novel compounds with unique properties for pharmaceutical, agricultural, or materials science applications.
🧪 Related Compounds
One similar compound to 5-Chlorosalicylic Acid based upon molecular structure is 3-Chlorosalicylic Acid. This compound contains a chloro group attached to the third carbon of the benzene ring, similar to the positioning of the chloro group in 5-Chlorosalicylic Acid. The presence of the hydroxyl group on the second carbon of the benzene ring in both compounds contributes to their similarity in molecular structure.
Another similar compound to 5-Chlorosalicylic Acid is 4-Chlorosalicylic Acid. In this compound, the chloro group is located on the fourth carbon of the benzene ring, leading to a molecular structure that is comparable to that of 5-Chlorosalicylic Acid. Like 5-Chlorosalicylic Acid, 4-Chlorosalicylic Acid also contains a hydroxyl group on the second carbon of the benzene ring, further contributing to their structural resemblance.
Additionally, a related compound to 5-Chlorosalicylic Acid is 2-Chlorosalicylic Acid. This compound features a chloro group attached to the second carbon of the benzene ring, similar to the positioning of the chloro group in 5-Chlorosalicylic Acid. The presence of the hydroxyl group on the third carbon of the benzene ring in both compounds further highlights their structural similarity.
