4-Pyridoxic acid, a metabolite of vitamin B6, plays a crucial role in various biological processes within the human body. It is involved in the synthesis of neurotransmitters, such as serotonin and dopamine, which are essential for regulating mood and behavior. Additionally, 4-Pyridoxic acid is important for the maintenance of healthy nerve and muscle function, as well as for the proper functioning of the immune system. Therefore, ensuring an adequate intake of vitamin B6, and subsequently 4-Pyridoxic acid, through dietary sources or supplements, is essential for overall health and well-being.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Pyridoxic acid, a metabolite of vitamin B6, finds limited commercial and industrial applications due to its primary role as a biomarker for vitamin B6 status in the body. It is predominantly utilized in research and clinical settings to assess the nutritional status and deficiency of vitamin B6 in individuals.
In the realm of drug and medication applications, 4-Pyridoxic acid plays a significant role in the pharmacokinetics of vitamin B6 supplements and medications. It is often used as a marker to monitor the absorption, metabolism, and excretion of vitamin B6 compounds in the body, aiding in the development and evaluation of pharmaceutical formulations containing vitamin B6.
Additionally, 4-Pyridoxic acid has been studied for its potential therapeutic applications in the treatment of various medical conditions, including certain neurological disorders and metabolic diseases. Research is ongoing to explore the drug-like properties and therapeutic benefits of 4-Pyridoxic acid, opening up new avenues for potential drug development in the future.
⚗️ Chemical & Physical Properties
4-Pyridoxic acid is a white crystalline solid with no distinct odor. It is known for its appearance as a fine powder, similar to sugar or salt found in common household items.
The molar mass of 4-Pyridoxic acid is approximately 169.18 g/mol, with a density of about 1.5 g/cm³. This places it in the range of common household items such as table salt (NaCl) with a molar mass of 58.44 g/mol and a density of 2.16 g/cm³.
4-Pyridoxic acid has a melting point of around 176-178°C and a boiling point of approximately 412°C. These values fall within the range of melting and boiling points commonly observed in household items such as sugar (melting point of 186°C) and water (boiling point of 100°C).
4-Pyridoxic acid is soluble in water, forming a clear solution, and has a low viscosity. This contrasts with substances like oil, which are not soluble in water and have a higher viscosity.
🏭 Production & Procurement
4-Pyridoxic acid, also known as pyridoxate, is a water-soluble degradation product of Vitamin B6 (pyridoxine). It is primarily produced in humans as a result of the metabolic breakdown of pyridoxine in the liver.
To procure 4-Pyridoxic acid for research or commercial purposes, it can be synthesized through chemical methods in a laboratory setting. Alternatively, it can also be extracted from biological sources such as human blood or urine.
The transportation of 4-Pyridoxic acid is typically done in sealed containers to prevent contamination or degradation during transit. It is important to store the compound in a cool, dry place to maintain its stability and potency.
When procuring 4-Pyridoxic acid, it is essential to ensure the purity and authenticity of the compound through rigorous quality control measures and analytical testing. Adherence to strict handling protocols is necessary to maintain the integrity of the compound for scientific research or industrial applications.
⚠️ Safety Considerations
Safety considerations for 4-Pyridoxic acid include proper storage, handling, and disposal of the compound. It is important to store 4-Pyridoxic acid in a cool, dry place away from direct sunlight and sources of ignition. When handling the compound, it is advisable to wear appropriate protective equipment such as gloves, goggles, and lab coat to prevent skin contact or inhalation of vapors. In case of accidental exposure, immediate medical attention should be sought, and the Material Safety Data Sheet for 4-Pyridoxic acid should be consulted for guidance on proper disposal methods.
The pharmacology of 4-Pyridoxic acid involves its role as a metabolite of Vitamin B6 (pyridoxine), which is essential for various biological processes in the body. 4-Pyridoxic acid is formed when Vitamin B6 is metabolized in the liver and excreted in the urine. It serves as a marker of Vitamin B6 status in the body and can be used clinically to assess Vitamin B6 deficiency or excess. Studies have shown that abnormalities in 4-Pyridoxic acid levels are associated with certain medical conditions, highlighting the importance of maintaining Vitamin B6 homeostasis for overall health.
Hazard statements for 4-Pyridoxic acid include the potential for skin and eye irritation upon contact with the compound. It is also classified as a hazardous substance due to its irritant properties and potential for respiratory sensitization. In case of exposure, symptoms such as redness, itching, or inflammation may occur, and appropriate first aid measures should be taken. It is important to read and understand the hazard statements provided on the packaging or Material Safety Data Sheet for 4-Pyridoxic acid to prevent any adverse effects.
Precautionary statements for 4-Pyridoxic acid include recommendations for safe handling and storage to minimize the risk of exposure. It is advised to use the compound in a well-ventilated area to prevent inhalation of vapors and to avoid direct contact with skin or eyes. Proper personal protective equipment should be worn when handling 4-Pyridoxic acid, and good hygiene practices should be followed to prevent accidental ingestion. In case of spills or leaks, appropriate containment measures should be taken, and the compound should be disposed of according to local regulations to prevent environmental contamination.
🔬 Potential Research Directions
Research on 4-Pyridoxic acid has shown its potential as a metabolite of vitamin B6 and a marker for vitamin B6 status in individuals. Future studies could investigate the relationship between 4-Pyridoxic acid levels and various health outcomes, such as cognitive function and cardiovascular health.
Furthermore, research could explore the role of 4-Pyridoxic acid in inflammatory processes and immune function. Understanding how this metabolite influences the immune response could provide insights into potential therapeutic interventions for inflammatory diseases.
Additionally, research on 4-Pyridoxic acid could delve into its potential as a biomarker for certain diseases or conditions. Studying the levels of this metabolite in different populations could help identify individuals at risk for vitamin B6 deficiency or specific health conditions.
Further investigations could also focus on the optimal methods for measuring 4-Pyridoxic acid levels in biological samples. Developing accurate and reliable assays for quantifying this metabolite could enhance its utility as a biomarker in clinical and research settings.
🧪 Related Compounds
One similar compound to 4-Pyridoxic acid based upon molecular structure is pyridoxal. Pyridoxal is an aldehyde form of vitamin B6 that is an essential cofactor for various enzymes involved in amino acid metabolism. Its molecular structure contains a pyridine ring with an aldehyde group attached at the C3 position.
Another similar compound is pyridoxamine, which is the amine form of vitamin B6. Pyridoxamine also serves as a cofactor for enzymes involved in amino acid metabolism. Its molecular structure includes a pyridine ring with an amino group attached at the C3 position, similar to pyridoxal.
Additionally, pyridoxine is a structural analogue of 4-Pyridoxic acid. Pyridoxine is the alcohol form of vitamin B6 and is converted to pyridoxal phosphate in the body, the active form of the vitamin. Its molecular structure contains a pyridine ring with a hydroxyl group attached at the C3 position, similar to pyridoxal.
