4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl-, commonly known as piperidinol, is a chemical compound that plays a crucial role in various industries. It is commonly used in the pharmaceutical sector for the synthesis of drugs such as antihistamines and antiviral medications. Additionally, it is utilized in the production of agricultural chemicals and rubber additives. In everyday life, piperidinol indirectly impacts consumers through its contributions to the development of essential products and medications. Its versatile properties make it a valuable component in multiple industrial applications.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
One commercial and industrial application of 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. This compound is utilized in the production of insecticides, herbicides, and certain types of medications.
Another commercial and industrial application of 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is in the manufacturing of rubber and plastic additives. This compound serves as a useful building block in the creation of specialized polymer materials with enhanced properties, such as improved durability and flexibility.
In terms of drug and medication applications, 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is utilized as a precursor in the synthesis of certain pharmaceutical drugs. This compound plays a crucial role in the creation of medications that target specific health conditions and diseases.
Furthermore, 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is used in the development of certain psychiatric medications due to its ability to modulate neurotransmitter activity in the brain. This compound is essential for the production of drugs that help regulate mood disorders and other mental health conditions.
⚗️ Chemical & Physical Properties
4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- typically appears as a colorless liquid with a mild, characteristic odor. This compound is commonly used as a building block in organic synthesis due to its versatile reactivity.
With a molar mass of approximately 159.28 g/mol and a density of around 0.92 g/cm³, 4-Piperidinol falls within the range of typical food items in terms of molar mass and density. For instance, sucrose has a molar mass of 342.3 g/mol and a density of 1.587 g/cm³.
4-Piperidinol has a relatively low melting point of -45°C and a boiling point of 152°C. In comparison to common food items, such as table salt with a melting point of 801°C and water with a boiling point of 100°C, 4-Piperidinol exhibits lower melting and boiling points.
This compound is soluble in water and has a moderate viscosity. Its solubility in water is similar to that of sugar, while its viscosity is akin to maple syrup. In comparison to common food items, 4-Piperidinol displays a higher viscosity than water but lower than honey.
🏭 Production & Procurement
4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is typically produced through a multi-step synthesis process starting from readily available starting materials such as piperidine and acetone. The synthesis involves several chemical reactions to introduce the hydroxyl group and tetramethyl substitutions onto the piperidine ring.
Once produced, 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- can be procured from chemical suppliers specializing in fine chemicals and specialty reagents. It is often packaged in sealed containers to prevent contamination and degradation during transportation. The compound can be transported via standard shipping methods such as ground transport or air freight.
Care should be taken when procuring and transporting 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- as it is a sensitive compound that can degrade under certain conditions. It is important to follow proper handling and storage procedures to maintain the integrity of the product. Additionally, safety precautions should be observed to prevent exposure to the chemical during handling and transport.
⚠️ Safety Considerations
Safety considerations for 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- must be taken seriously due to its potential hazards. This chemical compound should be stored in a cool, well-ventilated area away from incompatible materials. Proper personal protective equipment, such as gloves and safety goggles, should be worn when handling this substance to prevent skin contact and eye irritation. In case of accidental exposure, it is essential to seek medical attention immediately and follow appropriate first aid measures as necessary.
The hazard statements for 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- include the following: “Causes serious eye irritation” and “May cause respiratory irritation.” These statements indicate the potential risks associated with this chemical compound, highlighting the importance of using caution and following safety protocols when working with it. It is crucial to minimize exposure to this substance and take necessary precautions to protect oneself from its adverse effects.
Precautionary statements for 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- include the following: “Avoid breathing dust/fume/gas/mist/vapors/spray” and “Wear protective gloves/protective clothing/eye protection/face protection.” These statements emphasize the importance of practicing good chemical hygiene, such as proper ventilation and wearing appropriate personal protective equipment, to minimize the risks associated with handling this compound. It is crucial to follow these precautions to ensure the safety of individuals working with 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- and to prevent any potential harm or injury.
🔬 Potential Research Directions
Research on 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- could explore its potential as a pharmaceutical agent, particularly in the field of medicinal chemistry. This compound has displayed interesting bioactive properties that could be further analyzed for potential therapeutic applications.
Furthermore, studies could investigate the synthesis and modification of 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- to develop novel derivatives with improved activity or selectivity. This could lead to the discovery of new drug candidates with enhanced pharmacological profiles.
Additionally, research on the toxicological profile and metabolic fate of this compound could provide valuable insights into its safety and potential side effects. Understanding the mechanisms of action and potential toxicity of 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is crucial for its development as a pharmaceutical agent.
Finally, investigations could focus on the structure-activity relationship of 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- to elucidate the key structural features that are critical for its biological activity. This could guide the rational design of new derivatives with optimized properties for specific therapeutic applications.
🧪 Related Compounds
1. 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is a compound with a unique molecular structure that can be used as a reference point for identifying similar compounds. One such compound is 4-Piperidinol, 1-hydroxy-2,2,6,6-tetraethyl-, which has the same functional group as the original compound but differs in the length and type of alkyl groups attached to the nitrogen atom.
2. Another compound similar in structure to 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is 4-Piperidinol, 1-hydroxy-2-methyl-. In this compound, the alkyl group attached to the nitrogen atom is smaller in size than in the original compound, leading to differences in physical and chemical properties.
3. One more compound that shares similarities with 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl- is 4-Piperidinol, 1-hydroxy-2,6-dimethyl-. This compound has a similar alkyl group attached to the nitrogen atom as the original compound but lacks the additional methyl groups present in the tetramethyl compound, resulting in variations in reactivity and biological activity.
