4-Methylbenzyl alcohol, also known as p-cresol, is a compound commonly used as a fragrance ingredient in perfumes, soaps, and other cosmetic products. It is also utilized as a chemical intermediate in the production of pharmaceuticals, insecticides, and disinfectants. In everyday life, 4-Methylbenzyl alcohol plays a crucial role in enhancing the fragrance of personal care products and maintaining cleanliness through its disinfectant properties.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Methylbenzyl alcohol, also known as p-cresyl methylcarbinol, is utilized in various commercial and industrial applications. It is commonly used as a fragrance ingredient in perfumes, cosmetics, and personal care products due to its pleasant floral and fruity scent. Additionally, it is employed as a flavoring agent in food and beverages, providing a sweet and aromatic taste.
In the pharmaceutical industry, 4-Methylbenzyl alcohol has been investigated for its potential medicinal properties. Research suggests that it may possess antimicrobial and antioxidant properties, making it a promising candidate for the development of antimicrobial agents and antioxidant supplements. Furthermore, it has been explored for its potential role in the treatment of various skin conditions, such as acne and dermatitis, due to its anti-inflammatory and soothing properties.
Despite its commercial and medicinal applications, it is important to note that the use of 4-Methylbenzyl alcohol should be carefully regulated and monitored due to potential health risks associated with excessive exposure. This compound has been identified as a skin irritant and allergen, and prolonged or high-level exposure may lead to adverse effects on human health. Therefore, it is crucial to follow safety guidelines and regulations when handling products containing 4-Methylbenzyl alcohol to minimize the risk of adverse health effects.
⚗️ Chemical & Physical Properties
4-Methylbenzyl alcohol is a colorless liquid with a slightly sweet, floral odor. It is commonly used as a fragrance ingredient in the cosmetic and personal care industries.
The molar mass of 4-Methylbenzyl alcohol is 136.17 g/mol, and its density is approximately 1.04 g/cm3. In comparison to common household items, 4-Methylbenzyl alcohol has a higher molar mass than water (18.015 g/mol) but lower than sugar (342.30 g/mol), and its density is similar to that of water (1 g/cm3).
4-Methylbenzyl alcohol has a melting point of 18-20°C and a boiling point of 204-205°C. These values are lower than those of common household items such as table salt (melting point of 801°C) and water (boiling point of 100°C).
4-Methylbenzyl alcohol is slightly soluble in water, with a solubility of approximately 9.9 g/L at room temperature. It has a relatively low viscosity compared to common household items such as honey, with a viscosity similar to that of water.
🏭 Production & Procurement
4-Methylbenzyl alcohol, a chemical compound commonly used in the fragrance and flavor industries, is typically produced through the Friedel-Crafts alkylation reaction. In this process, toluene is alkylated with paraformaldehyde in the presence of a strong acid catalyst, such as hydrochloric acid or sulfuric acid, to yield the desired product.
Once produced, 4-Methylbenzyl alcohol can be procured from chemical suppliers specializing in aromatic compounds. The compound is commonly available in liquid form and can be purchased in varying quantities depending on the needs of the buyer. Due to its stable nature, 4-Methylbenzyl alcohol can be easily transported via traditional chemical shipping methods.
Transportation of 4-Methylbenzyl alcohol typically involves the use of standard chemical containers and appropriate labeling for identification and safety purposes. The compound is usually shipped in sealed containers to prevent leakage or contamination during transit. Proper handling practices should be observed to ensure the safe delivery of 4-Methylbenzyl alcohol to its intended destination.
⚠️ Safety Considerations
Safety considerations for 4-Methylbenzyl alcohol must be taken seriously, as it is a chemical compound that can pose risks if not handled properly. It is important to store 4-Methylbenzyl alcohol in a cool, dry, well-ventilated area away from incompatible materials. It is also crucial to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat when working with this compound to avoid skin contact or inhalation.
The pharmacology of 4-Methylbenzyl alcohol involves its use primarily as a fragrance ingredient in various cosmetic and personal care products. It is known for its pleasant floral scent and is often added to perfumes, lotions, and soaps to enhance their aroma. 4-Methylbenzyl alcohol is also utilized as a flavoring agent in food and beverages due to its sweet and fruity fragrance profile.
Hazard statements for 4-Methylbenzyl alcohol include “Causes skin irritation” and “May cause respiratory irritation” according to the labeling requirements. It is important to handle this chemical with caution and to avoid direct contact with skin or inhalation of vapors. In case of accidental exposure, appropriate first aid measures should be taken, and medical attention should be sought if necessary.
Precautionary statements for 4-Methylbenzyl alcohol include “Wear protective gloves/eye protection/face protection” and “Keep away from heat/sparks/open flames/hot surfaces.” It is crucial to follow proper safety protocols when working with this compound to minimize the risk of harm. In case of a spill, absorbent materials should be used to contain and clean up the substance, and proper disposal methods should be followed to prevent environmental contamination.
🔬 Potential Research Directions
One potential research direction for 4-Methylbenzyl alcohol is investigating its potential use as a flavoring agent in food products. This compound has a pleasant aroma and may be able to enhance the sensory characteristics of various food items.
Another area of exploration could be the study of 4-Methylbenzyl alcohol’s antimicrobial properties. Research could be conducted to determine its effectiveness in inhibiting the growth of bacteria and fungi, and its potential application in food preservation or medical settings.
Furthermore, researchers may explore the possibility of utilizing 4-Methylbenzyl alcohol in the development of new pharmaceutical drugs. Its chemical structure and properties could make it a promising candidate for drug discovery efforts, particularly in the fields of antiseptics or antibiotics.
Additionally, there may be interest in investigating the environmental impact of 4-Methylbenzyl alcohol. Studies could be conducted to assess its potential toxicity to aquatic life, its biodegradability, and its presence in environmental samples. This research could provide valuable information for regulatory agencies and industry stakeholders.
🧪 Related Compounds
One similar compound to 4-Methylbenzyl alcohol is 4-Ethylbenzyl alcohol. This compound has a similar molecular structure, with a benzene ring substituted with an ethyl group at the para position. The presence of the ethyl group imparts unique chemical properties to the compound compared to 4-Methylbenzyl alcohol.
Another related compound is 4-Isopropylbenzyl alcohol. Like 4-Methylbenzyl alcohol, this compound features a substituted benzene ring, but with an isopropyl group at the para position. The isopropyl group influences the chemical reactivity and physical properties of the molecule, making it distinct from 4-Methylbenzyl alcohol.
Additionally, 4-tert-Butylbenzyl alcohol is a compound that shares structural similarities with 4-Methylbenzyl alcohol. In this compound, a tert-butyl group is attached to the benzene ring at the para position. The presence of the bulky tert-butyl group results in unique steric effects and influences the compound’s behavior in chemical reactions.