4-Methoxyphenylacetic Acid, also known as p-Anisic Acid, is a chemical compound with various applications in everyday life. It is commonly used in the production of perfumes, flavorings, and pharmaceuticals. In the fragrance industry, it adds a sweet, floral note to perfumes and cosmetic products. In the food industry, it is used as a flavoring agent in foods and beverages. Additionally, it is employed in the synthesis of organic compounds used in pharmaceuticals, making it a crucial component in the development of medications. Overall, 4-Methoxyphenylacetic Acid plays a significant role in enhancing the sensory experiences and health outcomes of consumers in everyday life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Methoxyphenylacetic Acid, also known as p-anisic acid, finds various commercial and industrial applications due to its properties. It is commonly used as a fragrance ingredient in perfumes and cosmetics, adding a sweet, floral scent to the final product. Additionally, this compound is utilized as a precursor in the synthesis of pharmaceuticals and other organic compounds.
In the realm of drug and medication applications, 4-Methoxyphenylacetic Acid plays a crucial role in the pharmaceutical industry. It is utilized as an intermediate in the production of various pharmaceuticals, such as antihypertensive drugs and anti-inflammatory medications. Furthermore, this compound serves as a building block in the synthesis of biologically active molecules for medicinal purposes.
⚗️ Chemical & Physical Properties
4-Methoxyphenylacetic Acid is a white crystalline solid with a faint odor. It has a characteristic slightly sweet smell, similar to that of other aromatic carboxylic acids.
The molar mass of 4-Methoxyphenylacetic Acid is approximately 166.18 g/mol, and its density is around 1.18 g/cm3. These values are comparable to common food items such as sugar (molar mass of 342.3 g/mol, density of 1.59 g/cm3) and salt (molar mass of 58.44 g/mol, density of 2.16 g/cm3).
The melting point of 4-Methoxyphenylacetic Acid is approximately 154-156°C, while its boiling point is around 409-410°C. These values are higher than those of common food items such as butter (melting point of 32-35°C, boiling point of 99-100°C) and olive oil (melting point of -6 to -3°C, boiling point of 280°C).
4-Methoxyphenylacetic Acid is slightly soluble in water, with a viscosity similar to that of other carboxylic acids. This solubility and viscosity are lower compared to common food items such as sugar (high solubility, low viscosity) and salt (high solubility, high viscosity).
🏭 Production & Procurement
4-Methoxyphenylacetic acid, also known as p-anisic acid, is typically produced through a multistep synthesis starting from anisole. Anisole is first converted to p-bromoanisole through bromination, followed by hydrolysis to obtain p-anisic acid.
The procurement of 4-Methoxyphenylacetic Acid can be achieved through various chemical suppliers or manufacturers. It is commonly available in both bulk quantities for industrial use and smaller quantities for research purposes. The compound can be transported in sealed containers to prevent contamination or degradation during transit.
When procuring 4-Methoxyphenylacetic Acid, it is important to ensure proper handling and storage to maintain its purity and stability. It should be stored in a cool, dry place away from direct sunlight and incompatible materials. Additionally, proper labeling and documentation of the compound are necessary for regulatory compliance and safe handling practices.
⚠️ Safety Considerations
Safety considerations for 4-Methoxyphenylacetic Acid include the potential hazards associated with its handling and use. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when working with this compound to prevent skin contact and eye irritation. Additionally, 4-Methoxyphenylacetic Acid should be stored in a cool, dry place away from incompatible materials to avoid potential reactions or accidents. Proper ventilation is also crucial to prevent inhalation of vapors, which can cause respiratory irritation.
Hazard statements for 4-Methoxyphenylacetic Acid include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential risks associated with direct contact with the compound, emphasizing the importance of wearing protective gear when handling it. Ingestion or inhalation of 4-Methoxyphenylacetic Acid may also lead to adverse health effects, and therefore, it is essential to take precautions to prevent exposure.
Precautionary statements for 4-Methoxyphenylacetic Acid include “Wear protective gloves/eye protection” and “Wash hands thoroughly after handling.” These statements highlight the necessary safety measures to minimize the risks of skin and eye irritation when working with the compound. Additionally, it is advisable to avoid eating, drinking, or smoking while handling 4-Methoxyphenylacetic Acid to prevent accidental ingestion. Proper disposal of any contaminated materials is also crucial to prevent environmental hazards.
🔬 Potential Research Directions
One potential research direction for 4-Methoxyphenylacetic Acid is its role as a precursor in the synthesis of various pharmaceuticals and organic compounds. Investigation into the optimization of synthesis methods could lead to more efficient and cost-effective production processes.
Another area of interest could be the study of the biological activities of 4-Methoxyphenylacetic Acid and its derivatives. Understanding its potential therapeutic effects or biological pathways could pave the way for the development of new drugs or treatment strategies.
Furthermore, research could focus on the environmental fate and impact of 4-Methoxyphenylacetic Acid. Studies on its degradation pathways, toxicity to organisms, and potential for bioaccumulation could provide valuable insights for risk assessment and environmental management.
Lastly, exploration of the chemical reactivity and properties of 4-Methoxyphenylacetic Acid could uncover novel applications in fields such as materials science or catalysis. Investigation into its interactions with other molecules or surfaces could lead to the development of new materials or technologies.
🧪 Related Compounds
One similar compound to 4-Methoxyphenylacetic Acid is 4-Ethoxyphenylacetic Acid. This compound contains an ethoxy group (-OCH2CH3) in place of the methoxy group (-OCH3) found in 4-Methoxyphenylacetic Acid. The ethoxy group is larger than the methoxy group but has similar chemical properties.
Another similar compound is 4-Hydroxyphenylacetic Acid. This compound contains a hydroxy group (-OH) in place of the methoxy group found in 4-Methoxyphenylacetic Acid. The presence of a hydroxy group can significantly alter the compound’s solubility, reactivity, and biological activity compared to 4-Methoxyphenylacetic Acid.
Additionally, 4-Chlorophenylacetic Acid is a similar compound to 4-Methoxyphenylacetic Acid. In this compound, a chlorine atom (-Cl) is attached to the phenyl ring instead of a methoxy group. The chlorine atom can affect the compound’s electronic properties and reactivity compared to 4-Methoxyphenylacetic Acid.
