4-Fluorobiphenyl, a chemical compound derived from biphenyl in which a hydrogen atom is replaced by a fluorine atom, has various industrial applications that impact everyday life. It is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and liquid crystal materials. Additionally, it is utilized in the production of electronic materials and as a solvent in organic reactions. Its significance lies in its versatility and ability to contribute to the development of numerous products that play crucial roles in various aspects of society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Fluorobiphenyl, a chemical compound with the molecular formula C12H9F, has various commercial and industrial applications. It is used as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. Additionally, 4-Fluorobiphenyl is utilized in the synthesis of liquid crystals and organic light-emitting diodes (OLEDs) in the electronics industry.
In terms of drug and medication applications, 4-Fluorobiphenyl is not commonly used due to its toxic and potentially harmful effects. However, it is sometimes employed as a research tool in pharmaceutical development to study the behavior of organic compounds and their interactions with biological systems. Its chemical structure and properties make it a valuable compound for understanding structure-activity relationships in drug design.
Overall, while 4-Fluorobiphenyl has limited direct use in drug and medication applications, its versatility in chemical synthesis and its role as an intermediate in various industries make it a valuable compound in the realm of commercial and industrial chemistry. Its unique properties continue to be explored and utilized in diverse fields for the development of new materials and products.
⚗️ Chemical & Physical Properties
4-Fluorobiphenyl is a colorless solid with a slight aromatic odor. It is commonly used as a building block in organic synthesis and pharmaceuticals due to its unique chemical properties.
The molar mass of 4-Fluorobiphenyl is approximately 188.2 g/mol, with a density of around 1.16 g/cm³. This places it in the range of common food items such as sugar (molar mass 342.3 g/mol, density 1.59 g/cm³) and salt (molar mass 58.44 g/mol, density 2.16 g/cm³).
4-Fluorobiphenyl has a melting point of 35-37°C and a boiling point of 256-258°C. These values are much higher than those of common food items such as butter (melting point 30-35°C, boiling point 100°C) and water (melting point 0°C, boiling point 100°C).
4-Fluorobiphenyl is sparingly soluble in water and exhibits low viscosity. This is in contrast to common food items like salt (high solubility in water) and honey (high viscosity).
🏭 Production & Procurement
In the production of 4-Fluorobiphenyl, commonly used methods include the reaction of fluorobenzene with phenyl lithium or with other organometallic compounds such as phenyl lithium. These reactions typically take place under controlled conditions and involve the use of appropriate catalysts and reagents to ensure a high yield of the desired product. After the reaction is complete, the product is often purified through techniques such as distillation or chromatography to obtain a pure sample of 4-Fluorobiphenyl.
4-Fluorobiphenyl can be procured from chemical suppliers that specialize in the production and distribution of fine chemicals and intermediates. These suppliers typically offer 4-Fluorobiphenyl in various quantities and purities to meet the needs of different customers. Upon procurement, the compound is usually packaged and labeled according to regulatory standards to ensure safe handling and transport. Depending on the quantity and destination, 4-Fluorobiphenyl may be shipped by ground, air, or sea freight to reach its final destination.
Transporting 4-Fluorobiphenyl requires adherence to strict regulations governing the transportation of hazardous chemicals. It is essential to use appropriate packaging materials that are compatible with the compound to prevent leaks or spills during transit. Additionally, proper labeling and documentation must accompany the shipment to provide essential information about the contents, hazards, and emergency response procedures. To ensure safe and secure transport, carriers may also need to comply with specific safety protocols and regulations set forth by relevant authorities.
⚠️ Safety Considerations
Safety considerations for 4-Fluorobiphenyl, a chemical compound used primarily as a precursor in the production of pharmaceuticals and agrochemicals, must be carefully adhered to in order to prevent harm to human health and the environment. Due to its classification as a hazardous substance, proper handling procedures should be followed at all times. This includes wearing appropriate personal protective equipment such as gloves, goggles, and a lab coat when working with 4-Fluorobiphenyl to minimize the risk of exposure.
In addition to wearing protective gear, it is crucial to handle 4-Fluorobiphenyl in a well-ventilated area to prevent the inhalation of vapors. This compound should be stored in a cool, dry place away from sources of ignition and incompatible materials to reduce the risk of fire or chemical reactions. In case of a spill or leak, appropriate measures should be taken to contain and clean up the substance to prevent its release into the environment. Finally, proper disposal methods should be followed to ensure that 4-Fluorobiphenyl does not pose a threat to human health or the ecosystem.
Hazard statements for 4-Fluorobiphenyl primarily revolve around its potential to cause skin and eye irritation upon direct contact. It is also classified as harmful if swallowed or inhaled, with the potential to cause respiratory irritation and other adverse effects. In addition, 4-Fluorobiphenyl may be harmful to aquatic life if released into waterways, highlighting the importance of preventing its contamination of the environment.
Precautionary statements for 4-Fluorobiphenyl include wearing protective gloves and eye protection when handling the compound to prevent skin and eye irritation. It is recommended to work in a well-ventilated area and avoid breathing in vapors or dust particles. In case of skin contact, the affected area should be washed thoroughly with soap and water, while any contaminated clothing should be removed immediately. If 4-Fluorobiphenyl is swallowed or inhaled, medical attention should be sought promptly. Finally, proper storage, handling, and disposal procedures should be followed to minimize the risk of exposure and environmental contamination.
🔬 Potential Research Directions
One potential research direction for 4-Fluorobiphenyl lies in its application as a precursor in organic synthesis. By investigating the reactivity of this compound and its potential for forming complex molecules, researchers can expand the scope of organic reactions and create new pathways for chemical synthesis.
Furthermore, studies could explore the pharmacological properties of 4-Fluorobiphenyl and its derivatives, focusing on their potential as drug candidates. By assessing their bioavailability, toxicity, and pharmacokinetics, scientists can determine their suitability for pharmaceutical applications and potentially develop new treatments for various medical conditions.
Another avenue for research could involve investigating the environmental impact of 4-Fluorobiphenyl and its breakdown products. By studying its persistence in the environment, potential for bioaccumulation, and effects on ecosystems, researchers can assess the risks associated with its use and develop strategies for minimizing its environmental footprint.
Lastly, researchers may explore the industrial applications of 4-Fluorobiphenyl, such as its potential as a precursor in the synthesis of specialty chemicals or as a component in electronic materials. By optimizing its synthesis and studying its properties in different applications, scientists can unlock new opportunities for using this compound in various industries.
🧪 Related Compounds
One similar compound to 4-Fluorobiphenyl based upon molecular structure is 4-Chlorobiphenyl. In this compound, a chlorine atom replaces the fluorine atom at the fourth position on one of the phenyl rings. This substitution results in a similar overall structure and properties to 4-Fluorobiphenyl.
Another related compound is 4-Bromobiphenyl, where a bromine atom is added in place of the fluorine atom at the fourth position on one of the phenyl rings. This substitution results in a compound with similar chemical properties to 4-Fluorobiphenyl due to the shared structural features.
Additionally, 4-Iodobiphenyl is a compound similar to 4-Fluorobiphenyl, where an iodine atom is substituted for the fluorine atom at the fourth position on one of the phenyl rings. This alteration leads to similar structural characteristics and chemical behavior between the two compounds.
