Compound Profile

4-(Dimethylamino)biphenyl 

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4-(Dimethylamino)biphenyl is a compound that holds relevance to everyday life due to its applications in various industries. It is commonly utilized as a chemical intermediate in the production of dyes, pharmaceuticals, and optical brighteners. Additionally, this compound has been studied for its potential use in organic light-emitting diodes (OLEDs) and other electronic devices. Overall, 4-(Dimethylamino)biphenyl plays a crucial role in advancing technology and enhancing everyday products that we encounter in our daily lives.

Table of Contents:

💡  Commercial Applications

4-(Dimethylamino)biphenyl, also known as Michler’s base, has various commercial and industrial applications. It is commonly used as an intermediate in the production of dyes and pigments, specifically for the synthesis of triphenylmethane and xanthene dyes. Additionally, it is utilized as a photo-initiator in polymerization reactions for various applications such as printing inks and adhesives.

In terms of drug and medication applications, 4-(Dimethylamino)biphenyl is sometimes used as a precursor in the synthesis of pharmaceutical compounds. Specifically, it is utilized in the production of certain anti-malarial drugs and as a starting material for the synthesis of some antihistamines. However, its direct use as an active ingredient in pharmaceuticals is limited due to its potential toxicity and carcinogenic properties.

Overall, 4-(Dimethylamino)biphenyl plays a significant role in both commercial and industrial sectors, particularly in the production of dyes, pigments, and photo-initiators. Its applications in drug synthesis are more limited but nonetheless important in the pharmaceutical industry for the production of certain classes of medications. Despite its utility, precautions should be taken in handling this compound due to its potential health hazards.

⚗️  Chemical & Physical Properties

4-(Dimethylamino)biphenyl is a white crystalline solid that is odorless. It has a faint odor when exposed to air, described as slightly fishy or amine-like.

The molar mass of 4-(Dimethylamino)biphenyl is 197.26 g/mol, and its density is 1.088 g/cm3. Compared to common food items, such as sugar with a molar mass of 342.3 g/mol and a density of 1.59 g/cm3, 4-(Dimethylamino)biphenyl has a lower molar mass and density.

The melting point of 4-(Dimethylamino)biphenyl is approximately 82-84°C, and the boiling point is around 305-307°C. In comparison, common food items like butter have melting points around 32-35°C, and water boils at 100°C, showing higher melting and boiling points than 4-(Dimethylamino)biphenyl.

4-(Dimethylamino)biphenyl is sparingly soluble in water and has low viscosity. This contrasts with common food items like salt, which readily dissolves in water, and honey, which has high viscosity.

🏭  Production & Procurement

Producing 4-(Dimethylamino)biphenyl typically involves the reaction of aniline with dimethyl sulfate under basic conditions. This process results in the formation of the desired compound along with the release of methanol as a byproduct. This reaction is commonly carried out in a controlled laboratory setting to ensure proper conditions and yields.

To procure 4-(Dimethylamino)biphenyl, it can be commercially purchased from chemical suppliers specializing in organic compounds. The compound is typically available in varying quantities and purities to suit different needs and applications. Once procured, 4-(Dimethylamino)biphenyl can be transported in sealed containers under appropriate safety guidelines to prevent exposure to air or moisture.

When transporting 4-(Dimethylamino)biphenyl, it is important to follow safety regulations regarding the handling of hazardous chemicals. Proper labeling and packaging should be used to avoid any accidental leaks or spills during transit. Additionally, the compound should be stored in a cool, dry place away from sources of heat or ignition to prevent any potential risks associated with its chemical properties.

⚠️  Safety Considerations

Safety considerations for 4-(Dimethylamino)biphenyl must be taken seriously due to its classification as a hazardous substance. This compound is known to be harmful if swallowed, inhaled, or in contact with skin, and may cause irritation to the respiratory system, skin, and eyes. Proper safety equipment, such as goggles, gloves, and a lab coat, should be worn when handling 4-(Dimethylamino)biphenyl, and it should only be used in a well-ventilated area to minimize exposure to its toxic fumes.

Hazard statements for 4-(Dimethylamino)biphenyl include “Causes skin irritation,” “May cause an allergic skin reaction,” and “Causes serious eye irritation.” These statements indicate the potential risks associated with contact with this compound and emphasize the importance of taking necessary precautions to prevent harm. Users should be aware of these hazards and handle 4-(Dimethylamino)biphenyl with care to avoid any adverse effects on their health.

Precautionary statements for 4-(Dimethylamino)biphenyl include “Wash hands thoroughly after handling,” “Wear protective gloves/protective clothing/eye protection/face protection,” and “IF ON SKIN: Wash with plenty of soap and water.” These statements outline the recommended safety measures to protect individuals from potential harm when working with this compound. By following these precautions, users can minimize the risk of exposure and ensure their safety when handling 4-(Dimethylamino)biphenyl.

🔬  Potential Research Directions

One potential research direction for 4-(Dimethylamino)biphenyl involves investigating its role in organic light-emitting diodes (OLEDs) as a charge transport material due to its electron-donating properties. This could lead to the development of more efficient and cost-effective OLED devices.

Another possible research avenue is exploring the potential use of 4-(Dimethylamino)biphenyl in the field of organic photovoltaics (OPVs) as a donor material for optimizing light absorption and charge transport properties. This could lead to the design of more efficient and sustainable solar energy conversion devices.

Additionally, research on the synthesis and modification of 4-(Dimethylamino)biphenyl derivatives could be pursued to enhance its solubility, stability, and electronic properties for various optoelectronic applications. This could open up new opportunities for advancing the field of organic electronics and photonics.

Furthermore, the exploration of the biological and environmental implications of 4-(Dimethylamino)biphenyl and its derivatives could be a promising research direction to better understand their potential impact on human health and the environment. This could provide valuable insights for assessing the safety and sustainability of their use in various technological applications.

One similar compound to 4-(Dimethylamino)biphenyl based upon molecular structure is 4-(Diethylamino)biphenyl. In this compound, the dimethylamino group in 4-(Dimethylamino)biphenyl is replaced with a diethylamino group, resulting in a similar structure with slightly different chemical properties.

Another similar compound is 4-(Dipropylamino)biphenyl. In this compound, the dimethylamino group is substituted with a dipropylamino group, altering the steric and electronic effects on the biphenyl core.

Furthermore, 4-(Dibenzylamino)biphenyl is another compound similar to 4-(Dimethylamino)biphenyl. In this compound, the dimethylamino group is replaced with a dibenzylamino group, creating a similar structural motif with potential differences in reactivity and biological activity.

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