4-Chloroaniline is a chemical compound that is commonly used in the production of pharmaceuticals, dyes, and pesticides. Despite its significance in various industries, it is crucial to note that exposure to high levels of 4-Chloroaniline can pose serious health risks to both humans and the environment. Therefore, it is essential for manufacturers and regulators to adhere to strict safety protocols when handling this compound in order to prevent any negative consequences on public health and the ecosystem.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Chloroaniline, a chemical compound with the molecular formula C6H6ClN, has various commercial and industrial applications. It is commonly used as an intermediate in the production of dyes, pharmaceuticals, and agrochemicals. Its reactivity and versatility make it an essential component in the manufacturing of a wide range of products.
In the pharmaceutical industry, 4-Chloroaniline serves as a key building block for the synthesis of various drugs and medications. It is used in the production of analgesics, antipyretics, and anti-inflammatory drugs. Additionally, it is utilized in the manufacture of some herbicides and pesticides due to its effectiveness in controlling weeds and pests.
Overall, 4-Chloroaniline plays a crucial role in both commercial and industrial sectors. Its diverse applications make it a valuable compound in various industries, from textiles to pharmaceuticals. Its versatile nature and reactivity make it an indispensable component in the production of a wide range of products.
⚗️ Chemical & Physical Properties
4-Chloroaniline is a white to pale brown solid with a characteristic odor. It is typically described as having a slightly sweet, pungent smell when in its pure form.
The molar mass of 4-Chloroaniline is 127.57 g/mol, and it has a density of approximately 1.344 g/cm3. In comparison to common food items, 4-Chloroaniline has a higher molar mass and density than most fruits, vegetables, and meats.
4-Chloroaniline has a melting point of 70-73°C and a boiling point of 232°C. These values are significantly higher than those of common food items, such as water (melting point of 0°C, boiling point of 100°C).
4-Chloroaniline is sparingly soluble in water and has a low viscosity. In comparison to common food items, it is less soluble than sugar and salt, but more soluble than oils or fats. Its viscosity is similar to that of water.
🏭 Production & Procurement
4-Chloroaniline is primarily produced by the chlorination of aniline in the presence of a catalyst. This reaction typically takes place in a controlled environment and requires careful monitoring of temperature and pressure to ensure a high yield of the desired product.
Once synthesized, 4-Chloroaniline can be procured from chemical suppliers who specialize in the distribution of a wide range of industrial chemicals. The compound is often stored and transported in sealed containers to prevent contamination or degradation during transit.
Transportation of 4-Chloroaniline typically occurs via bulk shipments in drums or totes, depending on the quantity required by the end user. Due to its hazardous nature, the compound must be handled according to strict safety regulations to minimize the risk of spills or exposure to personnel involved in its transportation.
Overall, the production and procurement of 4-Chloroaniline involve a series of carefully controlled chemical reactions and logistical processes to ensure the quality and safety of the compound throughout its journey from the manufacturing plant to the end user.
⚠️ Safety Considerations
Safety Considerations for 4-Chloroaniline:
When handling 4-Chloroaniline, it is important to wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat, to prevent skin contact and inhalation of fumes. It should be stored in a cool, dry place away from direct sunlight and incompatible materials. Proper ventilation should be ensured in areas where 4-Chloroaniline is being used to minimize the risk of exposure.
In the event of accidental exposure to 4-Chloroaniline, it is crucial to seek medical attention immediately. In case of ingestion, do not induce vomiting and rinse mouth with water. For skin contact, wash affected area with soap and water. For eye contact, rinse eyes with water for several minutes while holding eyelids open.
Hazard Statements for 4-Chloroaniline:
4-Chloroaniline is toxic if swallowed, inhaled, or in contact with skin. It may cause severe skin burns and eye damage. Prolonged exposure to 4-Chloroaniline may result in serious health effects, including respiratory irritation and organ damage.
Precautionary Statements for 4-Chloroaniline:
When handling 4-Chloroaniline, it is essential to wear protective gloves, clothing, and eye protection. Avoid breathing in fumes and ensure proper ventilation in the work area. In case of accidental exposure, seek medical advice immediately and bring the Safety Data Sheet of 4-Chloroaniline for reference. Storage of 4-Chloroaniline should be in a tightly sealed container in a well-ventilated area, away from heat and sources of ignition.
🔬 Potential Research Directions
One potential research direction for 4-Chloroaniline is its environmental impact, particularly in relation to its toxicity and potential for bioaccumulation in aquatic systems. Studies could investigate its effects on aquatic organisms and potential risk to human health through exposure via contaminated water sources.
Another research direction could focus on the synthesis of novel derivatives of 4-Chloroaniline with enhanced properties, such as increased solubility, stability, or reactivity. This could involve modifying the molecular structure of 4-Chloroaniline through chemical reactions to create new compounds with improved characteristics for various industrial applications.
Additionally, research could explore the use of 4-Chloroaniline as a building block in the synthesis of pharmaceuticals and agrochemicals. By investigating its potential as a precursor for important compounds, researchers could discover new ways to utilize 4-Chloroaniline in the development of valuable products with diverse applications in the fields of medicine and agriculture.
Finally, studies could investigate the mechanisms of 4-Chloroaniline’s reactivity in various chemical reactions, which could provide valuable insights into its behavior and potential applications in organic synthesis. By understanding the underlying chemistry of 4-Chloroaniline, researchers may uncover new ways to harness its unique properties for the creation of innovative materials and compounds.
🧪 Related Compounds
One similar compound to 4-Chloroaniline based upon molecular structure is 2-Chloroaniline. This compound also contains a chlorine atom attached to the benzene ring, but it is located at the 2-position instead of the 4-position like in 4-Chloroaniline. This difference in substitution pattern can lead to variations in reactivity and biological activity compared to 4-Chloroaniline.
Another similar compound is 3-Chloroaniline, which shares the same basic structure as 4-Chloroaniline but with the chlorine atom located at the 3-position on the benzene ring. This positional isomerism can result in distinct properties and behavior of 3-Chloroaniline compared to 4-Chloroaniline, making it a compound of interest for further study and comparison.
Additionally, 4-Bromoaniline is a compound similar to 4-Chloroaniline in structure, but with a bromine atom instead of a chlorine atom attached to the benzene ring. While these two compounds have similar chemical properties due to the halogen substitution on the benzene ring, the presence of bromine instead of chlorine can lead to subtle differences in reactivity and interactions with other molecules.
