4′-(Chloroacetyl)acetanilide is a compound commonly used in the production of pharmaceuticals, specifically as an intermediate in the synthesis of various medications. Its relevance to everyday life lies in its role in the creation of drugs that are essential for the treatment of various medical conditions. From pain relief to managing chronic illnesses, the development of these medications relies on compounds like 4′-(Chloroacetyl)acetanilide to enable their production. Thus, this compound plays a crucial role in advancing healthcare and improving the quality of life for individuals around the world.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4′-(Chloroacetyl)acetanilide, commonly known as CAA, has several commercial and industrial applications. It is utilized in the manufacturing of dyes, particularly for the production of various colors for textiles and paints. Additionally, CAA is used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals due to its versatile chemical properties.
In the realm of drug and medication applications, 4′-(Chloroacetyl)acetanilide plays a significant role as a precursor in the synthesis of various analgesic and anti-inflammatory medications. Its chemical structure allows for the modification of functional groups, leading to the creation of new pharmaceutical compounds with improved efficacy and reduced side effects. Furthermore, CAA is used in the research and development of novel drug formulations for the treatment of various medical conditions.
⚗️ Chemical & Physical Properties
4′-(Chloroacetyl)acetanilide is a white crystalline solid with no distinct odor. The compound is typically odorless and has a moderate melting point compared to other organic compounds.
The molar mass of 4′-(Chloroacetyl)acetanilide is approximately 233.70 g/mol, and its density is around 1.36 g/cm³. In comparison, common food items such as salt (molar mass: 58.44 g/mol, density: 2.16 g/cm³) have lower molar mass and higher density.
The melting point of 4′-(Chloroacetyl)acetanilide is in the range of 170-174°C, while its boiling point is around 435°C. These values are significantly higher than those of common food items like sugar (melting point: 186°C, boiling point: 368°C).
4′-(Chloroacetyl)acetanilide has limited solubility in water and exhibits low viscosity. In comparison, common food items like sugar are highly soluble in water and are more viscous in nature.
🏭 Production & Procurement
4′-(Chloroacetyl)acetanilide is typically produced through a multi-step synthesis process involving the reaction of 4-chloroacetyl chloride with acetanilide. This reaction results in the formation of the desired product, 4′-(Chloroacetyl)acetanilide, which can then be purified and isolated.
Once produced, 4′-(Chloroacetyl)acetanilide can be procured from chemical suppliers specializing in fine chemicals and intermediates. The compound is typically packed in sealed containers and shipped under controlled conditions to ensure its stability and purity during transportation.
During transportation, 4′-(Chloroacetyl)acetanilide should be handled with care to prevent contamination and degradation. Proper labeling and documentation are essential to ensure the safe and secure transport of the compound to its destination. It is recommended to follow regulatory guidelines and best practices for handling and storing chemical compounds during transit.
⚠️ Safety Considerations
Safety considerations for 4′-(Chloroacetyl)acetanilide include potential hazards associated with its handling and storage. As a chemical compound, it is important to ensure proper ventilation when working with this substance to prevent inhalation of potentially harmful vapors. Additionally, personal protective equipment such as gloves, goggles, and lab coats should be worn to minimize skin contact and eye exposure.
Furthermore, it is crucial to store 4′-(Chloroacetyl)acetanilide in a cool, dry place away from sources of heat or ignition. This helps prevent the risk of fire or explosion due to its flammable properties. Proper labeling of containers containing this compound is essential to avoid any confusion or accidental ingestion by unaware individuals.
The hazard statements for 4′-(Chloroacetyl)acetanilide include its potential to cause skin and eye irritation upon contact. It may also be harmful if inhaled or swallowed, leading to respiratory issues or gastrointestinal discomfort. The compound is classified as harmful to aquatic life, presenting a risk of environmental damage if not properly contained and disposed of.
Precautionary statements for 4′-(Chloroacetyl)acetanilide emphasize the importance of avoiding direct contact with skin, eyes, and clothing. In case of exposure, thorough rinsing with water is recommended to remove any traces of the compound. Proper disposal methods should be followed to prevent contamination of water sources or soil, in accordance with local regulations and guidelines. Additionally, any spills or leaks should be promptly cleaned up using appropriate materials and procedures to minimize environmental impact.
🔬 Potential Research Directions
One potential research direction for 4′-(Chloroacetyl)acetanilide is its potential use in pharmaceutical research for the development of new drugs. The compound’s unique structure and properties make it a promising candidate for further investigation in the field of medicinal chemistry.
Further studies could focus on exploring the biological activities of 4′-(Chloroacetyl)acetanilide, such as its potential as an anti-inflammatory or analgesic agent. Understanding its mechanism of action and pharmacological profile could provide valuable insights for drug development.
Another area of research could involve investigating the toxicological effects of 4′-(Chloroacetyl)acetanilide. Assessing its safety profile and potential side effects is crucial for determining its suitability for use in pharmaceutical applications. This research could contribute to a better understanding of the compound’s overall risk-benefit profile.
Additionally, studies could be conducted to evaluate the environmental impact of 4′-(Chloroacetyl)acetanilide. Assessing its persistence, bioaccumulation, and potential ecological effects is essential for regulatory purposes and environmental protection. This research could inform decisions about the compound’s use and disposal to minimize its impact on ecosystems.
🧪 Related Compounds
One related compound to 4′-(Chloroacetyl)acetanilide based on its molecular structure is 4′-(Bromoacetyl)acetanilide. In this compound, the chlorine atom in the acetyl group has been replaced by a bromine atom. This substitution results in a similar overall structure with a halogen atom attached to the acetyl group.
Another compound with a structure akin to 4′-(Chloroacetyl)acetanilide is 4′-(Fluoroacetyl)acetanilide. Here, the chlorine atom is substituted with a fluorine atom in the acetyl group. Despite the difference in halogen atoms, both compounds share a common core structure with an acetanilide moiety attached to an acetyl group.
Additionally, 4′-(Iodoacetyl)acetanilide is a compound comparable to 4′-(Chloroacetyl)acetanilide in terms of molecular structure. In this compound, the chlorine atom is replaced by an iodine atom in the acetyl group. This alteration preserves the essential structure of an acetanilide molecule linked to an acetyl group, with the only variation being the identity of the halogen atom.
