4′-Chloroacetanilide is a chemical compound that has relevance in everyday life due to its use in the synthesis of various pharmaceuticals, dyes, and agrochemicals. This compound plays a crucial role in the production of analgesic and anti-inflammatory drugs, which are commonly used to alleviate pain and reduce inflammation in individuals suffering from various medical conditions. Additionally, 4′-Chloroacetanilide is utilized in the manufacturing of dyes that are employed in the textile industry to impart color to fabrics. Furthermore, this compound is integral in the development of agrochemicals that help boost crop yields and protect plants from pests and diseases. In conclusion, the compound 4′-Chloroacetanilide contributes significantly to improving the quality of life by supporting the pharmaceutical, textile, and agricultural sectors.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4′-Chloroacetanilide, a chemical compound commonly used in the commercial and industrial sectors, finds applications as an intermediate in the synthesis of various pharmaceuticals, dyes, and agrochemicals. Its versatile nature allows for incorporation into a wide range of products, including pesticides, herbicides, and pharmaceutical formulations.
In the pharmaceutical industry, 4′-Chloroacetanilide is utilized for its analgesic and anti-inflammatory properties. It serves as a precursor in the development of analgesic drugs such as paracetamol (acetaminophen) and phenacetin. Additionally, this compound can be found in certain over-the-counter medications aimed at alleviating pain and reducing fever.
Due to its effectiveness as a chemical building block, 4′-Chloroacetanilide also plays a crucial role in the synthesis of various specialty chemicals used in research and development. Its importance extends beyond the pharmaceutical industry, with applications in the production of high-performance polymers, antioxidants, and other specialty chemicals.
⚗️ Chemical & Physical Properties
4′-Chloroacetanilide is a white crystalline solid with a faint odor. It is a stable compound under normal conditions and has a low volatility.
The molar mass of 4′-Chloroacetanilide is approximately 171.6 g/mol, and its density is around 1.43 g/cm³. This molar mass is higher than common food items such as sugars and salts, while its density is similar to many organic compounds found in food.
The melting point of 4′-Chloroacetanilide is around 70-73°C, and its boiling point is around 285-288°C. These values are significantly higher compared to those of common food items, which typically have lower melting and boiling points.
4′-Chloroacetanilide is sparingly soluble in water but more soluble in organic solvents. It has a low viscosity, making it relatively easy to handle in laboratory settings. In comparison, common food items like sugar and salt are highly soluble in water and have different viscosity properties.
🏭 Production & Procurement
4’-Chloroacetanilide is typically produced through a multistep synthesis process involving the reaction of p-chloroaniline with acetic anhydride in the presence of a suitable catalyst. This reaction yields 4’-Chloroacetanilide as the desired product, which can then be isolated and purified through various techniques such as recrystallization or chromatography.
The procurement of 4’-Chloroacetanilide can be achieved through chemical suppliers or manufacturers specializing in fine chemicals. The compound is commonly available for purchase in various quantities, ranging from small research quantities to bulk quantities for industrial applications. Upon procurement, 4’-Chloroacetanilide can be safely transported using standard chemical handling and shipping procedures in compliance with regulatory guidelines.
When transporting 4’-Chloroacetanilide, it is crucial to ensure proper labeling and packaging to prevent potential leaks or spills. The compound should be handled with care to avoid exposure to skin, eyes, or inhalation of vapors. Additionally, appropriate measures should be taken to comply with regulations regarding the transport of hazardous chemicals to ensure the safety of individuals involved in the handling and delivery of the compound.
⚠️ Safety Considerations
When handling 4′-Chloroacetanilide, it is important to consider several safety precautions. This compound can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. It is vital to wear appropriate personal protective equipment, such as gloves and goggles, to minimize the risk of exposure. Additionally, 4′-Chloroacetanilide should be stored in a cool, dry, well-ventilated area away from incompatible substances to prevent any potential hazards.
Hazard statements for 4′-Chloroacetanilide include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements indicate the potential dangers associated with exposure to this compound. It is essential to handle 4′-Chloroacetanilide with caution and follow proper safety protocols to avoid any adverse effects on health.
Precautionary statements for 4′-Chloroacetanilide include “Wear protective gloves/eye protection/face protection,” “IF ON SKIN: Wash with plenty of water,” and “IF INHALED: Remove person to fresh air and keep comfortable for breathing.” These statements outline the necessary precautions to take when working with 4′-Chloroacetanilide to ensure the safety of individuals handling the compound. Following these guidelines will help minimize the risk of exposure and potential harm.
🔬 Potential Research Directions
One potential research direction for 4′-Chloroacetanilide is the study of its potential pharmaceutical applications. Researchers may explore the compound’s potential as a drug candidate for various diseases or conditions, examining its pharmacological activities and mechanisms of action.
Another area of interest could be investigating the environmental impact of 4′-Chloroacetanilide. Studies may focus on its persistence in the environment, bioaccumulation in organisms, and potential toxic effects on ecosystems. This research could provide valuable insights into the compound’s environmental behavior and potential risks.
Furthermore, the synthesis and optimization of 4′-Chloroacetanilide derivatives could be a fruitful research direction. Researchers may explore different synthetic routes to produce analogs with improved properties, such as increased efficacy or reduced toxicity. This work could lead to the development of new and improved compounds with potential applications in various fields.
Lastly, the elucidation of the metabolic pathways of 4′-Chloroacetanilide in biological systems could be an interesting avenue for research. Scientists may investigate how the compound is metabolized in the body, identifying its metabolites and understanding their potential biological effects. This research could provide valuable insights into the compound’s pharmacokinetic profile and potential interactions with other drugs.
🧪 Related Compounds
One similar compound to 4′-Chloroacetanilide based upon molecular structure is 4′-Bromoacetanilide. This compound shares a similar structure with 4′-Chloroacetanilide, but with a bromine atom in place of the chlorine atom. The presence of the bromine atom imparts different chemical properties to 4′-Bromoacetanilide compared to 4′-Chloroacetanilide.
Another compound with a molecular structure similar to 4′-Chloroacetanilide is 4′-Methoxyacetanilide. In this compound, a methoxy group is attached to the para position of the aniline ring, similar to how the chlorine atom is attached in 4′-Chloroacetanilide. Like 4′-Chloroacetanilide, 4′-Methoxyacetanilide is also used in various chemical reactions and synthesis processes.
One more compound worth mentioning is 4′-Nitroacetanilide, which shares a similar molecular structure with 4′-Chloroacetanilide. In this compound, a nitro group is substituted in place of the chlorine atom, resulting in different chemical properties and reactivity compared to 4′-Chloroacetanilide. Despite these differences, 4′-Nitroacetanilide is also utilized in various industrial applications and chemical processes.
