4-Chloro-3-nitrobenzoic acid is a chemical compound that has applications in various industries, including pharmaceuticals, agriculture, and research. In everyday life, this compound may not have direct relevance to the average individual. However, its role in these industries contributes to the development of new medications, pesticides, and scientific advancements that ultimately impact society as a whole.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Chloro-3-nitrobenzoic acid, a versatile chemical compound, finds various commercial and industrial applications. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and other organic compounds. Its ability to react with a wide range of functional groups makes it a valuable building block in the chemical industry.
In the realm of drug and medication applications, 4-Chloro-3-nitrobenzoic acid plays a significant role in the synthesis of active pharmaceutical ingredients (APIs). It is utilized in the production of certain drugs for its ability to enhance the bioavailability and efficacy of the final product. Pharmaceutical companies often rely on this compound as a key component in the development of new medications.
Furthermore, 4-Chloro-3-nitrobenzoic acid is employed in the manufacturing of herbicides and pesticides for agricultural purposes. Its chemical properties make it an effective agent in controlling pests and weeds, contributing to the overall productivity and sustainability of the agricultural sector. By incorporating this compound into pesticide formulations, farmers can effectively protect their crops from harmful organisms.
Overall, the commercial and industrial applications of 4-Chloro-3-nitrobenzoic acid are diverse and essential in various sectors. Its versatility and effectiveness in chemical reactions make it a valuable component in the production of pharmaceuticals, agrochemicals, and other organic compounds, contributing to advancements in science and technology.
⚗️ Chemical & Physical Properties
4-Chloro-3-nitrobenzoic acid is a white crystalline solid with no distinct odor. It appears as a fine powder and is typically odorless.
The molar mass of 4-Chloro-3-nitrobenzoic acid is 209.57 g/mol, and its density is 1.63 g/cm³. This molar mass is higher than common food items like sugar (180.16 g/mol) and salt (58.44 g/mol), while its density is similar to substances like olive oil (0.92 g/cm³) and milk (1.03 g/cm³).
The melting point of 4-Chloro-3-nitrobenzoic acid is approximately 166-168°C, while its boiling point is around 377-379°C. These values are much higher compared to common food items like butter (melting point of 32-35°C) and water (boiling point of 100°C).
4-Chloro-3-nitrobenzoic acid is sparingly soluble in water and has a low viscosity. This solubility is much lower compared to common food items like sugar, which is highly soluble in water, and the viscosity is lower than substances like honey, which has a higher viscosity.
🏭 Production & Procurement
4-Chloro-3-nitrobenzoic acid is typically produced through a nitration reaction involving 4-chlorobenzoic acid as the starting material. The reaction is carried out by treating 4-chlorobenzoic acid with a mixture of concentrated nitric acid and concentrated sulfuric acid to introduce the nitro group onto the benzene ring. This process is commonly used in organic synthesis to introduce nitro groups onto aromatic compounds.
In terms of procurement, 4-Chloro-3-nitrobenzoic acid can be obtained from chemical suppliers specializing in fine chemicals or custom synthesis services. It is typically available in bulk quantities and can be purchased in various purities depending on the intended application. The compound can be transported in solid form as a white crystalline powder or in solution form for ease of handling and storage.
When transporting 4-Chloro-3-nitrobenzoic acid, it is important to ensure proper labeling and packaging to prevent any accidental exposure or contamination. The compound is classified as a hazardous material due to its potential toxicity and should be handled with appropriate safety precautions. Transportation methods may vary depending on the quantity and purity of the compound, with options including ground shipping, air freight, or specialized chemical transport services.
⚠️ Safety Considerations
Safety considerations for 4-Chloro-3-nitrobenzoic acid include its classification as a hazardous substance due to its potential to cause skin and eye irritation. When handling this chemical, appropriate personal protective equipment such as gloves, goggles, and lab coats should be worn to prevent direct contact with the skin or eyes. In addition, it is important to work with 4-Chloro-3-nitrobenzoic acid in a well-ventilated area to minimize inhalation exposure.
Hazard statements for 4-Chloro-3-nitrobenzoic acid include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential for this chemical to cause harm if it comes into contact with the skin or eyes. It is important to take appropriate precautions when handling 4-Chloro-3-nitrobenzoic acid to avoid these hazards and protect oneself from potential injuries.
Precautionary statements for 4-Chloro-3-nitrobenzoic acid include “Wash hands thoroughly after handling” and “Wear protective gloves/protective clothing/eye protection/face protection.” These statements emphasize the importance of practicing good hygiene and using appropriate personal protective equipment when working with this chemical to minimize the risk of exposure and potential harm. By following these precautionary statements, individuals can safely handle 4-Chloro-3-nitrobenzoic acid and reduce the likelihood of adverse effects.
🔬 Potential Research Directions
One potential research direction for 4-Chloro-3-nitrobenzoic acid is its use as a building block in organic synthesis due to its unique structural properties. Research may focus on exploring the reactivity of this compound in various synthetic transformations to develop new strategies for the construction of complex organic molecules.
Another area of investigation could involve studying the pharmacological properties of 4-Chloro-3-nitrobenzoic acid to determine its potential therapeutic applications. Research may involve investigating its interactions with biological targets and assessing its potential as a drug candidate for the treatment of various diseases.
Furthermore, research on the environmental impact of 4-Chloro-3-nitrobenzoic acid may be warranted to understand its fate in the environment and evaluate any potential risks associated with its use. Studies could focus on its degradation pathways, persistence in the environment, and potential for bioaccumulation in organisms.
Lastly, investigation into the physical and chemical properties of 4-Chloro-3-nitrobenzoic acid could provide valuable insights into its behavior in various chemical processes. Research may involve studying its solubility, stability, and reactivity under different conditions to enhance our understanding of this compound’s behavior in practical applications.
🧪 Related Compounds
One similar compound to 4-Chloro-3-nitrobenzoic acid is 4-Chloro-2-nitrobenzoic acid. This compound differs from 4-Chloro-3-nitrobenzoic acid in the position of the nitro group on the benzene ring. While both compounds contain a chlorine substituent, the placement of the nitro group affects the overall chemical properties of the molecule.
Another similar compound is 4-Chloro-3-aminobenzoic acid. In this compound, the nitro group in 4-Chloro-3-nitrobenzoic acid is replaced by an amino group. This substitution alters the chemical reactivity and biological activity of the molecule, making it distinct from 4-Chloro-3-nitrobenzoic acid.
Additionally, 4-Chloro-3-methylbenzoic acid shares structural similarities with 4-Chloro-3-nitrobenzoic acid. In this compound, the nitro group is replaced by a methyl group, leading to differences in the physical and chemical properties of the molecule. Despite these variations, both compounds belong to the same chemical family and share some common characteristics.
