4-Chloro-3-nitrobenzenesulfonamide is a chemical compound with various practical applications in everyday life. It is commonly used in the pharmaceutical industry as an intermediate for the synthesis of drugs, such as antibacterial and antiviral agents. Additionally, it is utilized in the production of dyes, pigments, and agrochemicals. Its versatile properties and wide range of applications make it a valuable compound in various industries, ultimately impacting the products and goods that individuals use in their daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Chloro-3-nitrobenzenesulfonamide, also known by its chemical formula C6H5ClN2O4S, is primarily utilized in industrial processes as a precursor in the synthesis of various pharmaceutical compounds. This compound is commonly employed in the manufacturing of sulfonamide drugs, which are widely used for treating bacterial infections. In addition to its pharmaceutical applications, 4-Chloro-3-nitrobenzenesulfonamide is utilized in the dye industry for its ability to impart color to textiles and other materials.
In terms of commercial applications, 4-Chloro-3-nitrobenzenesulfonamide is a key ingredient in the production of herbicides and pesticides. Its chemical properties make it effective in targeting specific types of plant pathogens and pests, thereby aiding in agricultural crop protection. Furthermore, this compound is utilized in the production of rubber chemicals, as it can enhance the properties of rubber materials, particularly in terms of elasticity and durability.
4-Chloro-3-nitrobenzenesulfonamide exhibits pharmacological properties that have led to its use in the development of medications for various medical conditions. This compound is a crucial component in the synthesis of diuretic drugs, which are prescribed for the treatment of hypertension and edema. Additionally, 4-Chloro-3-nitrobenzenesulfonamide plays a role in the production of certain antiseptic agents, which are utilized for disinfecting wounds and preventing infections in healthcare settings.
⚗️ Chemical & Physical Properties
4-Chloro-3-nitrobenzenesulfonamide is a white crystalline solid with no distinct odor. It is sparingly soluble in water and exhibits a low viscosity in its pure form.
The molar mass of 4-Chloro-3-nitrobenzenesulfonamide is approximately 248.63 g/mol, and its density is around 1.63 g/cm³. This compound has a higher molar mass and density compared to common food items such as sugar or salt.
The melting point of 4-Chloro-3-nitrobenzenesulfonamide is around 175-177°C, while its boiling point is approximately 405-407°C. These values are significantly higher than those of common food items like butter or chocolate.
4-Chloro-3-nitrobenzenesulfonamide is sparingly soluble in water, with a solubility of less than 1 g/L at room temperature. It also has a lower viscosity compared to common food items like honey or syrup.
🏭 Production & Procurement
4-Chloro-3-nitrobenzenesulfonamide, also known as Chloramphenicol sulfonamide, is produced through a multistep process involving reactions between 4-chloronitrobenzene and sulfonyl chloride. The synthesis typically begins by nitration of benzene followed by selective chlorination and sulfonation steps to yield the final product.
Procuring 4-Chloro-3-nitrobenzenesulfonamide can be conducted through chemical suppliers, laboratory equipment suppliers, or specialized chemical manufacturers. The compound is typically transported in sealed containers to prevent exposure to moisture and light, which may cause degradation. Proper labeling and documentation adhering to safety regulations are required for the transportation of 4-Chloro-3-nitrobenzenesulfonamide.
The handling and storage of 4-Chloro-3-nitrobenzenesulfonamide should be conducted in a controlled environment to prevent deterioration or contamination. When procuring the compound, it is essential to obtain safety data sheets and follow proper safety precautions to minimize risks associated with its handling. Additionally, the compound should be stored in a cool, dry place away from sources of heat or direct sunlight to maintain its stability and purity.
⚠️ Safety Considerations
Safety considerations for 4-Chloro-3-nitrobenzenesulfonamide, also known as Triclosan, include potential health hazards and risks associated with exposure. Inhalation, ingestion, or skin contact with this compound can lead to irritation, allergic reactions, or even more severe health effects. Proper personal protective equipment, such as gloves, goggles, and a lab coat, should be worn when handling 4-Chloro-3-nitrobenzenesulfonamide to minimize the risk of exposure. Additionally, this compound should be stored in a secure location away from incompatible materials to prevent accidents or spills.
The hazard statements for 4-Chloro-3-nitrobenzenesulfonamide include being harmful if swallowed, causing skin irritation and serious eye irritation. This compound is also toxic to aquatic life with long-lasting effects. It is essential to handle 4-Chloro-3-nitrobenzenesulfonamide with caution to prevent adverse health effects on humans and harm to the environment. Proper disposal methods should be followed to minimize the impact on aquatic ecosystems.
Precautionary statements for 4-Chloro-3-nitrobenzenesulfonamide recommend avoiding breathing in dust or vapor and wearing protective gloves and eye protection when handling this compound. In case of skin contact, the affected area should be washed with plenty of water and soap, and contaminated clothing should be removed. If 4-Chloro-3-nitrobenzenesulfonamide comes into contact with the eyes, they should be rinsed cautiously with water for several minutes while removing contact lenses, if present. It is also crucial to dispose of this compound properly and in accordance with local regulations to prevent harm to the environment.
🔬 Potential Research Directions
One potential research direction for 4-Chloro-3-nitrobenzenesulfonamide is its use as a starting material for the synthesis of novel bioactive compounds. By introducing different functional groups to the molecule, researchers can explore its potential pharmacological properties.
Another research avenue is the investigation of the antimicrobial activity of 4-Chloro-3-nitrobenzenesulfonamide and its derivatives. Studies could focus on the mechanism of action against various pathogens, as well as the development of new antimicrobial agents based on this compound.
Additionally, the potential use of 4-Chloro-3-nitrobenzenesulfonamide in materials science and environmental applications is worth exploring. Its unique chemical structure may lend itself to applications such as dye sensitized solar cells, corrosion inhibitors, and wastewater treatment agents.
Furthermore, studies on the toxicity and environmental impact of 4-Chloro-3-nitrobenzenesulfonamide could provide valuable insights for its safe handling and disposal. Understanding its potential harmful effects on living organisms and ecosystems is crucial for the responsible use of this compound in various industries.
🧪 Related Compounds
One similar compound to 4-Chloro-3-nitrobenzenesulfonamide is 4-Chloro-2-nitrobenzenesulfonamide. This compound is structurally similar in that it has a chlorine atom and a nitro group attached to a benzene ring, along with a sulfonamide functional group. The difference lies in the position of the nitro group on the benzene ring, with 4-Chloro-2-nitrobenzenesulfonamide placing the nitro group at the 2-position.
Another similar compound is 4-Chloro-3-methylbenzenesulfonamide. This compound contains a chlorine atom attached to a benzene ring, along with a sulfonamide functional group. The difference lies in the presence of a methyl group at the 3-position of the benzene ring, instead of a nitro group.
One more similar compound is 4-Chloro-3-fluorobenzenesulfonamide. This compound has a chlorine atom and a fluorine atom attached to a benzene ring, along with a sulfonamide functional group. The difference lies in the presence of a fluorine atom at the 3-position of the benzene ring, instead of a nitro group.
