4-Bromobenzoic acid is a chemical compound that has relevance to everyday life due to its use in various industries such as pharmaceuticals, agrochemicals, and materials science. It serves as a key building block in the synthesis of medicines, pesticides, and advanced materials. Additionally, 4-Bromobenzoic acid is utilized in research laboratories for its versatile chemical properties. Its presence in everyday products may not be explicitly apparent, but its impact on these industries exemplifies its significance in society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Bromobenzoic acid, also known as p-bromobenzoic acid, is a chemical compound commonly used in various commercial and industrial applications. One significant use of 4-Bromobenzoic acid is as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. It is also utilized in the synthesis of other organic compounds, such as herbicides and insecticides.
In the pharmaceutical industry, 4-Bromobenzoic acid is utilized as a building block in the synthesis of various drugs and medications. It serves as a key component in the production of non-steroidal anti-inflammatory drugs (NSAIDs) and other pharmaceutical products. Additionally, 4-Bromobenzoic acid is used in the manufacturing of certain medications that possess antibacterial and antifungal properties.
Overall, the commercial and industrial applications of 4-Bromobenzoic acid are diverse and wide-ranging. Its unique chemical properties make it a valuable compound in the production of various organic molecules and pharmaceuticals. Additionally, its versatility in applications, including drug and medication synthesis, further highlights its importance in the chemical industry.
⚗️ Chemical & Physical Properties
4-Bromobenzoic acid is a white crystalline solid with a faint, sweet odor. It is sparingly soluble in water but more soluble in organic solvents such as acetone or ethanol.
The molar mass of 4-Bromobenzoic acid is approximately 201.10 g/mol, and its density is around 1.84 g/cm³. Comparatively, common food items like table salt (NaCl) have a molar mass of 58.44 g/mol and a density of 2.16 g/cm³.
The melting point of 4-Bromobenzoic acid is about 148-150°C, while its boiling point is approximately 332-333°C. When compared to common food items like sugar (sucrose), which melts at around 186°C and boils at 1,860°C, 4-Bromobenzoic acid has a lower melting and boiling point.
4-Bromobenzoic acid has limited solubility in water and exhibits a low viscosity. This is in contrast to common food items like sugar and salt, which are highly soluble in water and have a relatively low viscosity.
🏭 Production & Procurement
4-Bromobenzoic acid is typically produced through a halogenation reaction involving benzoic acid and bromine. This process involves the addition of bromine to the benzene ring of benzoic acid, resulting in the formation of 4-Bromobenzoic acid as the final product.
The procurement of 4-Bromobenzoic acid involves sourcing the necessary raw materials for production, including benzoic acid and bromine. These materials are typically obtained from chemical suppliers and manufacturers who specialize in providing high-quality reagents for chemical synthesis processes.
Once produced, 4-Bromobenzoic acid can be transported in various forms, including solid crystals or dissolved in a suitable solvent. The compound may be packaged in appropriate containers to ensure safe transportation and handling, following established guidelines and regulations for chemical transportation.
⚠️ Safety Considerations
Safety considerations for 4-Bromobenzoic acid are crucial due to its potential hazards. This compound may cause skin irritation, eye irritation, and respiratory irritation upon exposure. It is important to handle 4-Bromobenzoic acid with care, wearing appropriate personal protective equipment such as gloves, goggles, and a lab coat. Additionally, it is essential to work with this compound in a well-ventilated area to avoid inhalation of its vapors.
Hazard statements for 4-Bromobenzoic acid include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements are important to consider when working with this compound in a laboratory setting. It is essential to take necessary precautions to prevent exposure to 4-Bromobenzoic acid to avoid potential adverse effects on health.
Precautionary statements for 4-Bromobenzoic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “Use only outdoors or in a well-ventilated area.” These statements emphasize the importance of using appropriate personal protective equipment and working in a well-ventilated space when handling this compound. It is crucial to follow these precautions to minimize the risks associated with working with 4-Bromobenzoic acid.
🔬 Potential Research Directions
One potential research direction for 4-Bromobenzoic acid is exploring its use as a building block in organic synthesis, particularly in the development of new pharmaceutical compounds. The bromine substituent on the aromatic ring offers opportunities for selective functionalization, making it a valuable starting material for the synthesis of diverse chemical structures.
Another avenue of research could involve studying the reactivity of 4-Bromobenzoic acid towards various nucleophiles and electrophiles to understand its behavior in different reaction conditions. This could lead to the discovery of novel synthetic methodologies or the optimization of existing processes for the production of target molecules.
Additionally, investigations into the potential biological activities of 4-Bromobenzoic acid and its derivatives could open up new avenues for drug discovery and development. Understanding the molecular interactions of these compounds with biological targets may provide insights into their therapeutic potential and aid in the design of more effective pharmaceutical agents.
Furthermore, exploring the physicochemical properties of 4-Bromobenzoic acid, such as its solubility, stability, and crystal structure, could contribute to the development of improved formulations for drug delivery or other applications. This research could help optimize the performance of 4-Bromobenzoic acid-based materials in various industrial and scientific fields.
🧪 Related Compounds
One similar compound to 4-Bromobenzoic acid is 2-Bromobenzoic acid. This compound has a similar molecular structure to 4-Bromobenzoic acid, with the only difference being the position of the bromine atom on the benzene ring. Like 4-Bromobenzoic acid, 2-Bromobenzoic acid is utilized in organic synthesis and pharmaceutical research due to its reactivity and versatility.
Another compound with a comparable structure to 4-Bromobenzoic acid is 3-Bromobenzoic acid. This compound also contains a bromine atom attached to the benzene ring, albeit at a different position compared to 4-Bromobenzoic acid. 3-Bromobenzoic acid shares similar chemical properties and applications with its isomeric counterparts, making it a valuable reagent in various chemical reactions and processes.
One additional compound akin to 4-Bromobenzoic acid is 4-Chlorobenzoic acid. While this compound contains a chlorine atom instead of a bromine atom on the benzene ring, it shares a comparable molecular structure with 4-Bromobenzoic acid. 4-Chlorobenzoic acid exhibits similar reactivity and properties to 4-Bromobenzoic acid, making it a useful compound in organic synthesis and related fields.
