4′-Bromoacetophenone is a chemical compound that possesses various industrial and research applications. While it may not directly impact everyday life, it plays a crucial role in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Additionally, 4′-Bromoacetophenone is utilized in organic synthesis processes, aiding in the creation of new materials and compounds that contribute to scientific advancements and technological innovations. Its significance lies in its versatility and importance within the realm of chemical synthesis and industrial applications.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4′-Bromoacetophenone, a chemical compound with the molecular formula C8H7BrO, is predominantly used in commercial and industrial applications. It is commonly employed as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fragrance compounds. Additionally, 4′-Bromoacetophenone is utilized in the production of fine chemicals and specialty materials due to its versatility as a building block in organic synthesis processes.
In drug and medication applications, 4′-Bromoacetophenone is of particular interest in the pharmaceutical industry for its potential as a key starting material in the development of novel therapeutic agents. Its chemical structure and functional groups make it suitable for modification to create drug candidates with specific pharmacological activities. Moreover, researchers and manufacturers are exploring the use of 4′-Bromoacetophenone in medicinal chemistry to synthesize analogs and derivatives for drug discovery and development purposes.
⚗️ Chemical & Physical Properties
4′-Bromoacetophenone is a white crystalline solid with a pungent odor. It has a distinct aromatic scent that is characteristic of aromatic compounds.
The molar mass of 4′-Bromoacetophenone is approximately 205.1 g/mol, and it has a density of around 1.6 g/cm³. This molar mass and density are similar to common food items such as sugar and salt, making 4′-Bromoacetophenone relatively comparable in weight and volume.
The melting point of 4′-Bromoacetophenone is around 75°C, while the boiling point is approximately 271°C. These melting and boiling points are significantly higher than those of common food items such as butter and chocolate, indicating a higher level of thermal stability.
4′-Bromoacetophenone is sparingly soluble in water but more soluble in organic solvents. It has a moderate viscosity at room temperature. This solubility and viscosity are comparable to common food items like olive oil and honey, which also demonstrate limited solubility in water and moderate viscosity.
🏭 Production & Procurement
4′-Bromoacetophenone is typically produced through the Friedel-Crafts reaction between bromine and acetophenone. This reaction results in the substitution of a hydrogen atom on the aromatic ring with a bromine atom, yielding 4′-Bromoacetophenone as the final product. The reaction is typically carried out in the presence of a Lewis acid catalyst, such as aluminum chloride, under reflux conditions.
Once produced, 4′-Bromoacetophenone can be procured through various chemical suppliers and manufacturers. It is commonly available in both liquid and solid forms, depending on the specific needs of the end user. The compound is typically transported in sealed containers to prevent exposure to light and moisture, which can degrade its quality over time.
In order to ensure the safe transportation of 4′-Bromoacetophenone, proper labeling and packaging are essential. The compound should be stored in a cool, dry place away from incompatible chemicals and sources of heat or ignition. Additionally, it is important to consult the relevant safety data sheets and regulations before handling or transporting 4′-Bromoacetophenone to prevent any potential hazards or accidents.
⚠️ Safety Considerations
Safety considerations for 4′-Bromoacetophenone are of utmost importance due to its potential health hazards. This compound is irritating to the skin, eyes, and respiratory system and may cause allergic skin reactions. It is also flammable and should be stored away from sources of ignition. When handling 4′-Bromoacetophenone, personal protective equipment such as gloves, goggles, and a lab coat should be worn to minimize exposure.
The hazard statements for 4′-Bromoacetophenone include: “Causes skin irritation,” “Causes serious eye irritation,” and “May cause an allergic skin reaction.” These statements indicate the potential dangers associated with exposure to this compound. It is important to follow proper safety protocols when working with 4′-Bromoacetophenone to minimize the risk of harm.
Precautionary statements for 4′-Bromoacetophenone include: “Wear protective gloves/protective clothing/eye protection/face protection,” “IF ON SKIN: Wash with plenty of water,” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements provide guidance on how to safely handle and respond to exposure to 4′-Bromoacetophenone. It is essential to follow these precautions to protect oneself from potential harm.
🔬 Potential Research Directions
One potential research direction for 4′-Bromoacetophenone lies in its application as a building block for the synthesis of various organic compounds. Investigating the reactivity of the bromo group can lead to the development of new chemical pathways and strategies for organic synthesis.
Furthermore, the study of the pharmacological properties of 4′-Bromoacetophenone and its derivatives could potentially lead to the discovery of new drug candidates. Research in this area may involve exploring its interactions with biological targets and assessing its potential therapeutic effects.
Another avenue of research may involve the investigation of the environmental fate and toxicity of 4′-Bromoacetophenone. Understanding its behavior in the environment and its impact on ecosystems can help in developing strategies for its safe handling and disposal.
Moreover, the exploration of the physical and chemical properties of 4′-Bromoacetophenone, such as its solubility, melting point, and spectral characteristics, can provide valuable insights into its behavior in various chemical processes. This information can be useful for optimizing its use in different applications.
🧪 Related Compounds
4′-Chloroacetophenone is a compound similar to 4′-Bromoacetophenone. This compound has a chlorine atom in place of the bromine atom, resulting in a similar molecular structure. Like 4′-Bromoacetophenone, 4′-Chloroacetophenone is commonly used in organic synthesis and pharmaceutical research due to its reactive nature and ability to undergo various chemical reactions.
4′-Iodoacetophenone is another compound with a molecular structure similar to 4′-Bromoacetophenone. In this compound, an iodine atom replaces the bromine atom, resulting in similar chemical properties. 4′-Iodoacetophenone is often utilized in organic synthesis reactions and is known for its reactivity and ability to participate in various chemical transformations.
4′-Methylacetophenone is a compound that shares similarities with 4′-Bromoacetophenone in terms of molecular structure. In this compound, a methyl group is attached to the acetophenone moiety, providing similar chemical properties. 4′-Methylacetophenone is commonly used in organic synthesis reactions as a precursor to various compounds and is valued for its reactivity and versatility in chemical transformations.
