4-Bromo-2-methylaniline is a chemical compound that has relevance in everyday life due to its potential uses in pharmaceuticals, dyes, and agrochemicals. This compound can be found in various consumer products and industrial applications, including medications, textiles, and pesticides. Its properties make it a valuable ingredient in the creation of these products, contributing to advancements in healthcare, fashion, and agriculture. As such, the study and understanding of 4-Bromo-2-methylaniline play a significant role in various aspects of our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Bromo-2-methylaniline, also known as 2-Amino-4-bromotoluene, is commonly used in industrial settings as a key intermediate in the synthesis of various pharmaceuticals, dyes, and pigments. This compound is particularly useful in the production of azo dyes due to its excellent color properties and stability.
In commercial applications, 4-Bromo-2-methylaniline is often utilized in the manufacturing of hair dyes, textiles, and plastics. Its ability to impart vibrant and long-lasting color makes it a popular choice in the dyeing industry. Additionally, this compound is also used as a corrosion inhibitor in various metalworking processes.
In the realm of drug and medication applications, 4-Bromo-2-methylaniline serves as a valuable building block in the synthesis of pharmaceuticals such as antitumor agents, antibiotics, and antimalarial drugs. Its versatile chemical structure allows for the creation of diverse drug compounds with targeted biological activities, making it an essential component in drug discovery and development processes.
⚗️ Chemical & Physical Properties
4-Bromo-2-methylaniline, also known as 2-Amino-4-bromotoluene, is a white crystalline solid with a faint odor. It is commonly used as an intermediate in the synthesis of various organic compounds.
The molar mass of 4-Bromo-2-methylaniline is approximately 197.07 g/mol, with a density of 1.45 g/cm3. This places it in the range of molar mass and density similar to common food items such as sugar and salt.
The melting point of 4-Bromo-2-methylaniline is around 32-34°C, while the boiling point is approximately 253-255°C. These values are higher compared to common food items such as butter or chocolate.
4-Bromo-2-methylaniline is sparingly soluble in water, and exhibits low viscosity. This contrasts with common food items like vinegar or honey, which are more soluble in water and have higher viscosity.
🏭 Production & Procurement
4-Bromo-2-methylaniline is typically produced through a multi-step synthesis involving the bromination of aniline followed by the methylation of the resulting bromoaniline compound. This process requires the use of specialized equipment and reagents to ensure the purity and yield of the final product.
In order to procure 4-Bromo-2-methylaniline, one must typically contact a chemical supplier or manufacturer who specializes in the production of aromatic amines and related compounds. The compound is often available in various quantities, ranging from small research-scale quantities to larger bulk quantities for industrial use.
Once procured, 4-Bromo-2-methylaniline must be transported in accordance with established safety guidelines for the handling and transportation of hazardous chemicals. Proper labeling, packaging, and documentation are required to ensure compliance with regulatory requirements and to prevent accidents or incidents during transit.
⚠️ Safety Considerations
Safety considerations for 4-Bromo-2-methylaniline include its potential for causing skin and eye irritation upon contact. It is important to handle this chemical in a well-ventilated area to avoid inhalation of vapors. Additionally, it is recommended to wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat, when handling 4-Bromo-2-methylaniline to minimize the risk of exposure.
Hazard statements for 4-Bromo-2-methylaniline include “Causes skin and eye irritation” and “May cause respiratory irritation.” This chemical should be handled with care to avoid any potential harm to skin, eyes, or respiratory system. It is important to avoid direct contact with 4-Bromo-2-methylaniline and to use appropriate safety measures to prevent exposure.
Precautionary statements for 4-Bromo-2-methylaniline include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF ON SKIN: Wash with plenty of water.” It is important to follow these precautions to minimize the risk of harm when handling this chemical. Proper handling and disposal procedures should be followed to ensure the safety of individuals working with 4-Bromo-2-methylaniline.
🔬 Potential Research Directions
Potential research directions for 4-Bromo-2-methylaniline could include investigating its application as a building block in the synthesis of various pharmaceuticals or agrochemicals. Furthermore, studies exploring its potential use in organic electronic devices or as a precursor in the production of dyes and pigments are areas for further exploration.
Another research avenue for 4-Bromo-2-methylaniline could involve investigating its reactivity towards different reagents and under various conditions to understand its chemical behavior and potential applications in organic synthesis. Additionally, exploring its potential biological activities and toxicity profile could provide valuable insights for its utilization in medicinal chemistry or environmental studies.
Further research could focus on developing efficient and environmentally friendly methods for the synthesis of 4-Bromo-2-methylaniline to improve its accessibility and reduce production costs. Additionally, exploring the potential of functionalizing its aromatic ring to introduce novel properties or functional groups could open up new avenues for its use in materials science or chemical engineering applications.
Investigating the potential interactions of 4-Bromo-2-methylaniline with metal ions or other molecules could offer insights into its coordination chemistry and potential applications as a ligand in coordination complexes. Moreover, exploring its behavior under different reaction conditions or in different solvents could provide a deeper understanding of its reactivity and pave the way for novel synthetic strategies or applications in catalysis.
🧪 Related Compounds
One similar compound to 4-Bromo-2-methylaniline based upon molecular structure is 4-Chloro-2-methylaniline. In this compound, the bromine atom in 4-Bromo-2-methylaniline is replaced with a chlorine atom, resulting in a similar molecular structure. Both compounds have a phenyl ring with a methyl group attached to carbon 2.
Another similar compound is 4-Iodo-2-methylaniline. In this compound, the bromine atom in 4-Bromo-2-methylaniline is replaced with an iodine atom. The presence of both a methyl group and a halogen atom on the phenyl ring is a common feature in these compounds.
Additionally, 4-Fluoro-2-methylaniline is another compound with a similar molecular structure to 4-Bromo-2-methylaniline. In this compound, the bromine atom is substituted with a fluorine atom. The presence of both a methyl group and a halogen atom on the phenyl ring makes these compounds structurally similar.