4-Aminobutanal is a chemical compound that plays a key role in various everyday applications. It is used in the production of pharmaceuticals, agrochemicals, and flavoring agents. Additionally, 4-Aminobutanal is utilized in the manufacturing of polymers and dyes. Its versatility and importance in multiple industries make it a significant component in modern society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Aminobutanal, also known as butanalamine, serves various commercial and industrial applications. It is used as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, 4-Aminobutanal is utilized in the production of certain fragrances and flavors due to its unique chemical properties.
In the domain of drug and medication applications, 4-Aminobutanal is of particular interest. Its derivative, gabapentin, is a widely prescribed medication for various neurological disorders such as epilepsy and neuropathic pain. The synthesis of gabapentin involves the conversion of 4-Aminobutanal into the desired drug product, highlighting the crucial role of this compound in the pharmaceutical industry. This underscores the importance of 4-Aminobutanal in the realm of medicinal chemistry and drug development.
⚗️ Chemical & Physical Properties
4-Aminobutanal is a colorless liquid with a strong ammonia-like odor. Its appearance is similar to that of other aldehydes, and its distinctive smell may be recognizable in a laboratory setting.
With a molar mass of 89.12 g/mol and a density of approximately 0.935 g/cm^3 at room temperature, 4-Aminobutanal falls within the range of common household items in terms of molar mass and density. It is lighter than many common liquids like water and oils.
The melting point of 4-Aminobutanal is around -7 degrees Celsius, while its boiling point is approximately 171 degrees Celsius. These values fall within a typical range for organic compounds and are comparable to substances like ethanol and acetone in terms of melting and boiling points.
4-Aminobutanal is soluble in water to a moderate extent, forming a clear solution. Its viscosity is relatively low compared to many household items, flowing easily like water. In comparison, substances like sugar and salt dissolve more readily in water and may exhibit higher viscosities.
🏭 Production & Procurement
4-Aminobutanal, also known as 4-aminobutyraldehyde, is typically produced through the oxidation of 1,4-diaminobutane. This process involves the use of oxidizing agents such as potassium permanganate or sodium dichromate to convert the diamine compound into the desired aldehyde product.
In terms of procurement, 4-Aminobutanal can be obtained from chemical suppliers or manufacturers specializing in aldehyde compounds. The compound is usually available in a purified form, packaged in appropriate containers to ensure stability during transport. Proper handling procedures should be followed to prevent degradation or contamination of the product.
Transporting 4-Aminobutanal requires adherence to regulatory guidelines for the shipment of hazardous materials. The compound may be classified as a hazardous substance due to its potential reactivity and toxicity. Depending on the quantity and destination, transportation may need to be arranged through specialized carriers equipped to handle hazardous chemicals. Companies involved in the supply chain must ensure compliance with safety regulations to minimize risks during transit.
⚠️ Safety Considerations
Safety considerations for 4-Aminobutanal include its potential to cause irritation to the skin, eyes, and respiratory tract. It is important to handle this compound in a well-ventilated area and to wear appropriate personal protective equipment, such as gloves and safety goggles. In case of contact with the skin or eyes, it is recommended to flush the affected area with plenty of water and seek medical attention if irritation persists.
The pharmacology of 4-Aminobutanal involves its potential as a precursor in the synthesis of pharmaceuticals and other organic compounds. This compound can react with other chemicals to form derivatives that may have biological activity. However, 4-Aminobutanal itself is not commonly used for medicinal purposes due to its potential toxicity and irritant properties.
Hazard statements for 4-Aminobutanal include its classification as a skin irritant and a respiratory irritant. This compound can cause irritation upon contact with the skin, eyes, and mucous membranes. It may also cause respiratory irritation if inhaled. It is important to handle this compound with caution and to follow proper safety protocols to minimize the risk of exposure.
Precautionary statements for 4-Aminobutanal include the recommendation to wear appropriate personal protective equipment, such as gloves, safety goggles, and a lab coat, when handling this compound. It is also important to work in a well-ventilated area to minimize exposure to vapors. In case of accidental exposure, it is recommended to seek medical attention and to have the Safety Data Sheet readily available for reference.
🔬 Potential Research Directions
One potential research direction for 4-Aminobutanal lies in exploring its potential use as a building block in the synthesis of various pharmaceuticals and agrochemicals. By investigating its reactivity and functional group transformations, researchers can uncover new synthetic pathways for the production of valuable compounds.
Another area of interest is the study of the biological activity of 4-Aminobutanal and its derivatives. Understanding how this compound interacts with biological systems can lead to the development of novel drugs with improved efficacy and reduced side effects. Research in this area could potentially uncover new therapies for a range of diseases.
Additionally, researchers may investigate the environmental impact of 4-Aminobutanal and its degradation products. Studies on the compound’s stability in different environmental conditions and its potential toxicity to organisms can provide valuable insights into its environmental fate and potential risks to ecosystems. This knowledge can inform regulatory decisions and guide the safe handling and disposal of 4-Aminobutanal.
Furthermore, researchers may explore the potential use of 4-Aminobutanal in materials science and catalysis. By studying its ability to participate in chemical reactions, researchers can develop new materials with unique properties and catalytic processes for the production of fine chemicals. This research can lead to the discovery of innovative technologies with applications in various industrial sectors.
🧪 Related Compounds
One similar compound to 4-Aminobutanal based on molecular structure is 4-Aminopentanal. This compound has a similar chain length but differs by having an additional carbon atom in the chain. This extra carbon creates a longer linear structure with similar functional groups.
Another related compound is 4-Aminobutanone, which is structurally similar to 4-Aminobutanal but with a ketone functional group instead of an aldehyde. This substitution results in a change in reactivity and properties while maintaining the overall structure of the molecule. The presence of the carbonyl group alters the compound’s chemical behavior compared to 4-Aminobutanal.
4-Aminopentanone is another analogous compound to 4-Aminobutanal, but with an additional carbon atom in the chain. This change in chain length affects the physical and chemical properties of the compound while preserving the amino and carbonyl functional groups. The longer carbon chain may influence the compound’s solubility, boiling point, and reactivity compared to 4-Aminobutanal.
