4-Acetylbiphenyl is a compound that has significance in everyday life due to its applications in various industries. It is commonly used in the production of pharmaceuticals, agrochemicals, and fragrances. Additionally, it is utilized in the synthesis of organic chemicals and as a research compound in the field of chemistry. Its versatility and importance in these sectors make it a relevant component in our daily lives, albeit indirectly.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Acetylbiphenyl, also known as acetophenone, is a key building block in the production of pharmaceuticals, fragrances, and various other chemical compounds. It is often used as a flavoring agent and in the production of vinyl polymers.
In commercial and industrial applications, 4-Acetylbiphenyl is commonly used as a solvent and chemical intermediate in the manufacturing of organic chemicals and pharmaceuticals. It is utilized in the synthesis of various drugs, dyes, and perfumes due to its aromatic properties and versatile chemical structure.
In drug and medication applications, 4-Acetylbiphenyl is often utilized as an intermediate in the production of pharmaceutical drugs. It is involved in the synthesis of various medications such as analgesics, anti-inflammatories, and antispasmodics. Its chemical structure allows for the modification of functional groups to create different drug compounds with specific pharmacological effects.
⚗️ Chemical & Physical Properties
4-Acetylbiphenyl is a white crystalline solid with a faint odor. Its appearance is described as powdery or granular, and it is often used in organic synthesis.
With a molar mass of 198.24 g/mol and a density of 1.09 g/cm3, 4-Acetylbiphenyl is heavier than common food items like sugar and salt. Its density is similar to that of vegetable oil.
The melting point of 4-Acetylbiphenyl is around 77-79°C, while its boiling point is approximately 260-265°C. These values are significantly higher than those of common food items, such as butter and chocolate, which melt and boil at lower temperatures.
4-Acetylbiphenyl is sparingly soluble in water and exhibits low viscosity. This contrasts with common food items like sugar and salt, which are highly soluble in water and may have varying viscosities.
🏭 Production & Procurement
4-Acetylbiphenyl is typically produced through the Friedel-Crafts acylation reaction, which involves the reaction of biphenyl with acetyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride. This reaction results in the substitution of a hydrogen atom on the biphenyl molecule with an acetyl group, forming 4-Acetylbiphenyl.
The procurement of 4-Acetylbiphenyl can be achieved through various chemical suppliers or manufacturers who produce and distribute this compound on a commercial scale. Transportation of 4-Acetylbiphenyl is typically done in sealed containers or drums to prevent exposure to moisture and air, which could degrade the compound. It is essential to handle and transport 4-Acetylbiphenyl with care, following proper safety protocols to avoid contamination and ensure the integrity of the product.
When procuring 4-Acetylbiphenyl, it is crucial to verify the purity and quality of the compound through analytical testing methods, such as spectroscopy or chromatography. Additionally, proper storage conditions should be maintained to prevent degradation or impurity formation, ensuring the compound’s stability and efficacy. Overall, the production and procurement of 4-Acetylbiphenyl involve meticulous attention to detail and adherence to best practices in chemical handling and transportation.
⚠️ Safety Considerations
Safety Considerations for 4-Acetylbiphenyl:
When handling 4-Acetylbiphenyl, it is vital to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to prevent skin contact, eye irritation, and inhalation of the substance. This compound should be stored in a well-ventilated area away from heat sources and incompatible materials. In case of accidental exposure, it is important to rinse affected areas with plenty of water and seek medical attention if necessary.
Hazard Statements for 4-Acetylbiphenyl:
4-Acetylbiphenyl is classified as a hazardous substance that may cause skin irritation, eye irritation, and respiratory tract irritation upon contact or inhalation. This compound is also harmful if swallowed, leading to gastrointestinal discomfort and potential health risks. Additionally, 4-Acetylbiphenyl may pose environmental hazards if released into the water or soil, impacting aquatic life and vegetation.
Precautionary Statements for 4-Acetylbiphenyl:
To minimize risks associated with 4-Acetylbiphenyl, it is recommended to wear suitable protective clothing, gloves, and eye protection when handling this compound. Avoid breathing in vapors or dust, and ensure adequate ventilation in the work area to prevent inhalation exposure. In case of spills or leaks, promptly clean up the area using absorbent materials and dispose of waste properly according to local regulations.
🔬 Potential Research Directions
One potential research direction for 4-Acetylbiphenyl could explore its reactivity and potential applications in organic synthesis. This could involve investigating its behavior in various chemical reactions and studying its potential as a building block for the synthesis of more complex compounds.
Another possible area of research could focus on the biological activity of 4-Acetylbiphenyl. This could involve evaluating its interactions with biological molecules and exploring its potential as a pharmaceutical agent. Understanding its biological effects could lead to the development of new drugs or therapies.
Further research could be directed towards the environmental fate and toxicity of 4-Acetylbiphenyl. This could involve studying its degradation pathways in the environment and assessing its potential impact on human health and the ecosystem. Such research could provide valuable information for risk assessment and environmental management strategies.
Additionally, research could be conducted to explore the potential industrial applications of 4-Acetylbiphenyl. This could involve investigating its properties as a chemical intermediate or its potential use in various industries. Understanding its industrial applications could lead to the development of new products or processes.
🧪 Related Compounds
One comparable compound to 4-Acetylbiphenyl, with structural similarities, is 4-Phenylacetophenone. This compound also consists of two benzene rings connected by a carbonyl group. The difference lies in the substitution of the acetyl group in 4-Acetylbiphenyl with a phenyl group in 4-Phenylacetophenone.
Another compound that shares structural characteristics with 4-Acetylbiphenyl is 1,2-Diphenylethanone. This compound contains two phenyl groups attached to a carbonyl group, similar to the structure of 4-Acetylbiphenyl. The main distinction between the two compounds is the location of the carbonyl group, which is situated on the central carbon in 1,2-Diphenylethanone instead of the side chain as in 4-Acetylbiphenyl.
An additional compound with a molecular structure akin to 4-Acetylbiphenyl is 4,4′-Dimethoxybenzophenone. This compound also consists of two benzene rings connected by a carbonyl group, similar to the structure of 4-Acetylbiphenyl. The key difference lies in the presence of methoxy groups at the para position of both benzene rings in 4,4′-Dimethoxybenzophenone, which distinguishes it from 4-Acetylbiphenyl.
