4-Acetyl-4′-nitrobiphenyl 

4-Acetyl-4′-nitrobiphenyl is a chemical compound that is relevant to everyday life due to its potential uses in various industries. It is commonly used in the production of dyes, pharmaceuticals, and other chemical products. Additionally, it has been studied for its potential applications in organic synthesis and material science. Understanding the properties and uses of 4-Acetyl-4′-nitrobiphenyl can provide insights into its impact on the environment and human health, making it an important subject of research and discussion.

Table of Contents:

💡  Commercial Applications

4-Acetyl-4′-nitrobiphenyl, also known as ANB, has several commercial and industrial applications. It is commonly used in the production of dyes, particularly yellow and red colored dyes, due to its vibrant and stable color properties. ANB is also utilized in the manufacturing of optical brighteners, which are added to detergents and textiles to enhance brightness and whiteness.

In the pharmaceutical industry, 4-Acetyl-4′-nitrobiphenyl is employed in the synthesis of various drugs and medications. It has been studied for its potential as an anti-inflammatory agent, as well as its role in cancer treatment due to its ability to inhibit certain enzymes. Additionally, ANB is utilized in the production of sunscreen products, where it acts as a UV filter to protect the skin from harmful UV rays.

⚗️  Chemical & Physical Properties

4-Acetyl-4′-nitrobiphenyl is a yellow crystalline solid with no distinctive odor.

The molar mass of 4-Acetyl-4′-nitrobiphenyl is approximately 267.247 g/mol, and its density is around 1.34 g/cm³. Compared to common food items like sugar (molar mass of 342.3 g/mol) and water (density of 1 g/cm³), 4-Acetyl-4′-nitrobiphenyl has a lower molar mass and a higher density.

The melting point of 4-Acetyl-4′-nitrobiphenyl is around 171-174°C, and its boiling point is approximately 410-413°C. In comparison, common food items like table salt have a much higher melting point (801°C) and boiling point (1,413°C).

4-Acetyl-4′-nitrobiphenyl is sparingly soluble in water and has a low viscosity. Compared to common food items like sugar (high solubility in water) and honey (high viscosity), 4-Acetyl-4′-nitrobiphenyl displays lower solubility in water and viscosity.

🏭  Production & Procurement

Producing 4-Acetyl-4′-nitrobiphenyl involves a multi-step synthesis process starting with commercially available starting materials. The first step typically involves the reaction of an appropriate substituted benzene with a chloroacetylating agent to form an intermediate. This intermediate is then reacted with a nitration reagent to yield the final product.

4-Acetyl-4′-nitrobiphenyl can be procured from chemical suppliers specializing in fine chemicals or custom synthesis services. The compound is usually available in a pure form, typically as a crystalline solid. Transportation of 4-Acetyl-4′-nitrobiphenyl is typically done under controlled conditions to ensure its stability and purity during transit.

For smaller quantities, 4-Acetyl-4′-nitrobiphenyl can be purchased online from reputable chemical suppliers. For larger industrial-scale quantities, custom synthesis services may be utilized to produce the compound according to specific requirements. Proper handling and storage practices should be followed to maintain the integrity of 4-Acetyl-4′-nitrobiphenyl during procurement and transportation.

⚠️  Safety Considerations

Safety considerations for 4-Acetyl-4′-nitrobiphenyl should be taken seriously due to its classification as a hazardous chemical. This compound is known to cause skin and eye irritation upon contact. It is also classified as harmful if swallowed or inhaled. Therefore, appropriate personal protective equipment should be worn when handling this substance, including gloves, goggles, and a lab coat. Additionally, proper ventilation is crucial to prevent inhalation of vapors. In case of accidental exposure, immediate medical attention should be sought.

The hazard statements for 4-Acetyl-4′-nitrobiphenyl include “Causes skin and eye irritation” and “Harmful if swallowed or inhaled.” These statements indicate the potential dangers associated with this chemical and highlight the importance of taking necessary precautions when handling it. It is essential to minimize exposure to 4-Acetyl-4′-nitrobiphenyl to prevent any adverse health effects.

Precautionary statements for 4-Acetyl-4′-nitrobiphenyl include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing.” These statements emphasize the importance of using proper personal protective equipment when working with this compound and highlight the need to remove contaminated clothing to prevent further exposure. It is crucial to follow these precautionary measures to ensure the safe handling of 4-Acetyl-4′-nitrobiphenyl and minimize the risk of harm.

🔬  Potential Research Directions

One potential research direction for 4-Acetyl-4′-nitrobiphenyl focuses on its chemical properties, such as its reactivity with other compounds and its potential applications in organic synthesis.

Another avenue of research could involve investigating the toxicological effects of 4-Acetyl-4′-nitrobiphenyl, including its potential carcinogenicity and any adverse health effects it may have on humans and the environment.

Additionally, researchers may explore the environmental fate of 4-Acetyl-4′-nitrobiphenyl, including its persistence in soil and water, as well as its potential for bioaccumulation in organisms.

Further research could also delve into the synthesis of derivatives of 4-Acetyl-4′-nitrobiphenyl to explore their unique properties and potential applications in various fields, such as pharmaceuticals or materials science.

One similar compound to 4-Acetyl-4′-nitrobiphenyl based on molecular structure is 4-Acetyl-4′-bromobiphenyl. This compound also contains a biphenyl backbone with an acetyl group and a bromine atom at positions 4 and 4′ respectively. The presence of the bromine atom instead of the nitro group can lead to different chemical properties and reactivity compared to 4-Acetyl-4′-nitrobiphenyl.

Another related compound is 4-Acetyl-4′-chlorobiphenyl, which shares a similar structure with 4-Acetyl-4′-nitrobiphenyl but contains a chlorine atom at position 4′ instead of a nitro group. The substitution of the nitro group with a chlorine atom can also result in varying chemical properties and potential differences in reactivity.

Similarly, 4-Acetyl-4′-methylbiphenyl is a compound with a structure akin to 4-Acetyl-4′-nitrobiphenyl, but with a methyl group at position 4′ instead of a nitro group. The presence of the methyl group can influence the compound’s physical and chemical properties, potentially leading to varied behaviors compared to 4-Acetyl-4′-nitrobiphenyl.

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