4-(2-Aminopropyl)phenol, also known as octapamine, is a compound that plays a significant role in everyday life. This chemical serves as a neurotransmitter and neuromodulator in the central nervous system of various organisms, including humans. It is involved in various physiological processes, such as regulating mood, stress response, and behavior. Additionally, octapamine has been studied for its potential therapeutic applications in the treatment of depression, anxiety, and cognitive disorders. As such, understanding the function and effects of 4-(2-Aminopropyl)phenol can provide valuable insights into the complexities of human biology and behavior.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-(2-Aminopropyl)phenol, also known as PAP, has various commercial and industrial applications. It is commonly used as a chemical intermediate in the production of pharmaceuticals, agrochemicals, and rubber chemicals. PAP is also utilized as a corrosion inhibitor in the metalworking industry and as a stabilizer in the polymer industry.
In terms of drug and medication applications, 4-(2-Aminopropyl)phenol plays a crucial role in the development of certain pharmaceuticals. It is utilized as a building block in the synthesis of various drugs, including antihistamines, bronchodilators, and antimalarial agents. PAP is also used in the production of analgesics and antipyretics due to its pharmacological properties.
Moreover, 4-(2-Aminopropyl)phenol is employed in the formulation of medications for treating respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It acts as a bronchodilator, helping to relax the muscles in the airways and improve breathing in patients with these conditions. PAP’s therapeutic properties make it a valuable component in the pharmaceutical industry for developing effective respiratory medications.
⚗️ Chemical & Physical Properties
4-(2-Aminopropyl)phenol is a white crystalline solid with a faint odor. It appears as small crystals or powder, and has a slightly bitter taste when dissolved in water.
The molar mass of 4-(2-Aminopropyl)phenol is approximately 153.21 g/mol, with a density of around 1.033 g/cm³. This places it within the range of molar masses and densities commonly found in food items like sugar and salt.
The melting point of 4-(2-Aminopropyl)phenol is around 110-112°C, while the boiling point is approximately 308-310°C. These properties are comparable to those of common food items like butter and chocolate in terms of melting and boiling points.
4-(2-Aminopropyl)phenol is sparingly soluble in water, but readily dissolves in organic solvents. It has a low viscosity in solution, similar to many food items such as vinegar or olive oil. Its solubility in water and viscosity are in line with those of common household cooking ingredients.
🏭 Production & Procurement
4-(2-Aminopropyl)phenol, also known as p-Aminopropylphenol, is typically produced through a multi-step synthesis process. The starting materials for this synthesis include phenol and 1,2-dichloropropane. Through a series of reactions, including alkylation and reduction steps, 4-(2-Aminopropyl)phenol is ultimately obtained as the final product.
Once produced, 4-(2-Aminopropyl)phenol can be procured from chemical suppliers or manufacturers. It is commonly available in both liquid and solid forms, depending on the specific requirements of the end user. The compound can be transported in sealed containers or drums, following proper safety protocols and regulations for handling hazardous chemicals.
For large-scale production and procurement of 4-(2-Aminopropyl)phenol, industrial companies often rely on established chemical suppliers or contract manufacturers. These suppliers can provide the compound in bulk quantities to meet the demands of various industries, such as pharmaceuticals, cosmetics, and specialty chemicals. Prior to shipment and delivery, proper documentation and safety data sheets are typically provided to ensure compliance with regulatory requirements.
⚠️ Safety Considerations
Safety considerations for 4-(2-Aminopropyl)phenol include the potential for skin and eye irritation. It is important to handle this compound with care and use appropriate personal protective equipment such as gloves and goggles. In addition, proper ventilation should be ensured when working with 4-(2-Aminopropyl)phenol to prevent inhalation of fumes.
Hazard statements for 4-(2-Aminopropyl)phenol include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential risks associated with coming into contact with this compound. It is important to be cautious when handling 4-(2-Aminopropyl)phenol to avoid skin and eye irritation.
Precautionary statements for 4-(2-Aminopropyl)phenol include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.” These statements outline the necessary precautions that should be taken when working with 4-(2-Aminopropyl)phenol to minimize the risk of exposure and potential harm. It is crucial to follow these precautionary measures to ensure safe handling of this compound.
🔬 Potential Research Directions
One potential research direction for 4-(2-Aminopropyl)phenol is to investigate its potential medical applications, particularly in the field of pharmacology. Studies could focus on its possible uses as a pharmaceutical agent, such as in the treatment of neurological disorders or as an analgesic.
Another area of interest could be the chemical synthesis of 4-(2-Aminopropyl)phenol derivatives to explore their structure-activity relationships. This could help in the development of novel compounds with improved pharmacological properties or increased efficacy. Furthermore, studying the interactions of these derivatives with biological targets could provide valuable insights into their mechanism of action.
Research could also be directed towards understanding the metabolic fate of 4-(2-Aminopropyl)phenol in the body, including its absorption, distribution, metabolism, and excretion. Investigating its biotransformation pathways and identifying potential biomarkers could enhance our knowledge of its pharmacokinetics and help in optimizing dosing regimens.
Lastly, exploring the potential toxicological effects of 4-(2-Aminopropyl)phenol and its derivatives could be an important research direction. Assessing their safety profile in preclinical models and elucidating any potential adverse effects could aid in the development of safe and effective therapeutic agents. Additionally, investigating their environmental impact and potential for bioaccumulation could be of interest in ensuring their sustainable use.
🧪 Related Compounds
One similar compound to 4-(2-Aminopropyl)phenol is 4-(2-Aminopropyl)aniline. This compound has a similar molecular structure to 4-(2-Aminopropyl)phenol, but with an amine group instead of a phenol group. The presence of the amine group gives 4-(2-Aminopropyl)aniline different chemical properties and reactivity compared to 4-(2-Aminopropyl)phenol.
Another similar compound to 4-(2-Aminopropyl)phenol is 4-(2-Hydroxypropyl)aniline. This compound also has a similar molecular structure to 4-(2-Aminopropyl)phenol, but with a hydroxyl group instead of an amino group. The presence of the hydroxyl group can affect the compound’s solubility and interactions with other molecules, making 4-(2-Hydroxypropyl)aniline distinct from 4-(2-Aminopropyl)phenol.
Additionally, another similar compound to 4-(2-Aminopropyl)phenol is 4-(2-Aminopropyl)benzoic acid. This compound features a similar molecular structure to 4-(2-Aminopropyl)phenol, but with a carboxylic acid group instead of a phenol group. The carboxylic acid group can influence the compound’s acidity and ability to form salts, distinguishing 4-(2-Aminopropyl)benzoic acid from 4-(2-Aminopropyl)phenol.