3,5-Dimethylpyridine, also known as collidine, plays a significant role in everyday life through its various applications in the chemical industry and other sectors. This compound is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, 3,5-Dimethylpyridine is utilized as a catalyst in organic reactions, particularly in the production of rubber chemicals and dyes. Therefore, the continued production and use of 3,5-Dimethylpyridine have a direct impact on the development and availability of essential products that serve consumers worldwide.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3,5-Dimethylpyridine, also known as lutidine, has several significant commercial and industrial applications. It is commonly used as a building block in the synthesis of various chemicals, including pharmaceuticals, pesticides, and agrochemicals. Additionally, 3,5-Dimethylpyridine is utilized in the manufacture of rubber antioxidants, dyes, and flame retardants.
In terms of drug and medication applications, 3,5-Dimethylpyridine plays a crucial role in the pharmaceutical industry. It is used as a precursor in the synthesis of several drugs, including antihistamines, proton pump inhibitors, and fungicides. Furthermore, 3,5-Dimethylpyridine is employed as a complexing agent in the formulation of certain types of medications.
Overall, the versatility and usefulness of 3,5-Dimethylpyridine make it an indispensable compound in various commercial, industrial, and pharmaceutical applications. Its unique properties and reactivity allow for the synthesis of a wide range of valuable products that benefit society in numerous ways.
⚗️ Chemical & Physical Properties
3,5-Dimethylpyridine is a colorless to pale yellow liquid with a strong, unpleasant odor reminiscent of burning tobacco. It is commonly used as a solvent in chemical reactions and as an intermediate in the production of pharmaceuticals and agrochemicals.
With a molar mass of 109.15 g/mol and a density of 0.930 g/cm³, 3,5-Dimethylpyridine is heavier than common food items like water and vinegar, but lighter than vegetable oil. Its molecular weight suggests it is relatively small compared to larger molecules found in food.
3,5-Dimethylpyridine has a melting point of -66°C and a boiling point of 167-168°C. These properties are higher than common food items like butter and sugar, but lower than vegetable oil and honey. The compound is known for its sharp boiling point range, making it suitable for precise chemical processes.
In water, 3,5-Dimethylpyridine is partially soluble as a polar organic compound. It exhibits low viscosity, making it easily miscible in aqueous solutions. Compared to common food items, its solubility in water is similar to alcohol and vinegar, while its viscosity is closer in nature to water and milk.
🏭 Production & Procurement
3,5-Dimethylpyridine, also known as collidinium, is typically produced through a multi-step synthesis process involving the reaction of formaldehyde, acetaldehyde, and ammonia. This reaction yields a mixture of 3,5-Dimethylpyridine along with other pyridine derivatives, which must be separated and purified to isolate the desired compound.
Once 3,5-Dimethylpyridine has been produced and purified, it can be procured from chemical suppliers who specialize in the production and distribution of fine chemicals. The compound is typically available in liquid form, packaged in drums or smaller containers for ease of handling and transportation.
In order to transport 3,5-Dimethylpyridine, proper safety precautions must be taken due to its flammable and potentially hazardous nature. The compound should be stored and transported in accordance with local regulations and guidelines for handling hazardous materials. Specialized containers and transportation methods may be required to ensure the safe delivery of 3,5-Dimethylpyridine to its intended destination.
⚠️ Safety Considerations
Safety Considerations for 3,5-Dimethylpyridine:
The chemical compound 3,5-Dimethylpyridine poses several safety considerations that must be taken into account when handling or working with it. This compound is flammable and may ignite if exposed to sources of ignition, such as heat, sparks, or flames. Therefore, it should be stored in a cool, well-ventilated area away from any potential ignition sources. Additionally, 3,5-Dimethylpyridine may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Proper personal protective equipment, such as gloves, goggles, and a respirator, should be worn when working with this compound to prevent any potential health risks.
Hazard Statements for 3,5-Dimethylpyridine:
The hazard statements associated with 3,5-Dimethylpyridine include “Highly flammable liquid and vapor,” indicating the potential fire hazard posed by this compound. Additionally, it is classified as a skin irritant and may cause irritation to the eyes and respiratory system upon contact or inhalation. Furthermore, it is important to avoid any sources of ignition when working with 3,5-Dimethylpyridine to prevent the risk of fire or explosion.
Precautionary Statements for 3,5-Dimethylpyridine:
When working with 3,5-Dimethylpyridine, several precautionary measures should be taken to ensure the safety of individuals handling this compound. It is recommended to keep the compound away from heat, sparks, and open flames to prevent any potential fire hazards. In addition, proper ventilation should be maintained in the work area to minimize exposure to vapor or fumes. It is important to wear appropriate personal protective equipment, such as gloves, goggles, and a respirator, to protect against skin, eye, and respiratory irritation. Furthermore, any spills or leaks of 3,5-Dimethylpyridine should be cleaned up promptly and disposed of according to proper waste disposal guidelines to prevent environmental contamination.
🔬 Potential Research Directions
One potential research direction for 3,5-Dimethylpyridine could involve its use in pharmaceutical applications as a building block for the synthesis of novel drug compounds. By investigating the structural modifications and reactivity of 3,5-Dimethylpyridine, researchers may discover new lead compounds with enhanced biological activity and improved pharmacokinetic properties.
Another promising area of study could focus on the role of 3,5-Dimethylpyridine in catalysis. Understanding the catalytic activity of this compound in various chemical reactions could lead to the development of more efficient and sustainable catalytic processes. By exploring the mechanism of action and reactivity of 3,5-Dimethylpyridine in different catalytic systems, researchers may uncover valuable insights for the design of new catalysts.
Additionally, researchers may explore the potential environmental and toxicological implications of 3,5-Dimethylpyridine. By investigating its fate in the environment, bioaccumulation potential, and toxic effects on organisms, scientists can assess the environmental risks associated with the use and disposal of 3,5-Dimethylpyridine. This research could provide valuable information for the development of regulations and guidelines for the safe handling and disposal of this compound.
🧪 Related Compounds
One similar compound to 3,5-Dimethylpyridine is 2,4-Dimethylpyridine. This compound has a similar molecular structure to 3,5-Dimethylpyridine, with methyl groups located at the 2 and 4 positions on the pyridine ring. Like 3,5-Dimethylpyridine, 2,4-Dimethylpyridine is also used in the synthesis of various organic compounds.
Another compound similar to 3,5-Dimethylpyridine is 2,6-Dimethylpyridine. This compound shares the same molecular formula as 3,5-Dimethylpyridine (C7H9N), but with the methyl groups positioned at the 2 and 6 positions on the pyridine ring. 2,6-Dimethylpyridine is commonly used as a ligand in coordination chemistry, similar to 3,5-Dimethylpyridine.
A third similar compound to 3,5-Dimethylpyridine is 2,3-Dimethylpyridine. This compound is structurally related to 3,5-Dimethylpyridine, with methyl groups attached to the 2 and 3 positions on the pyridine ring. 2,3-Dimethylpyridine is utilized in the production of pharmaceuticals, pesticides, and other organic compounds, much like its 3,5-Dimethylpyridine counterpart.