3-Sulfoalanine is a non-proteinogenic amino acid that has significant relevance to various industries and everyday life. This compound is commonly used in the production of biotechnological products such as enzymes and antibodies. Additionally, 3-Sulfoalanine is utilized in the pharmaceutical industry to develop new drugs and therapies. Its unique properties make it an essential component in chemical research and development, contributing to advancements in medicine and biotechnology that impact society at large.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Sulfoalanine, also known as 3-ASA, is primarily used as a chiral building block in the chemical synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Its ability to introduce a sulfonic acid group makes it a valuable intermediate in the production of complex molecules. Additionally, 3-Sulfoalanine has found applications in the manufacturing of specialty polymers and materials due to its unique chemical properties.
In the realm of drug and medication applications, 3-Sulfoalanine plays a crucial role as a key intermediate in the synthesis of certain antibiotics, antiviral drugs, and cancer-treating agents. Its incorporation into the molecular structure of these pharmaceuticals imparts desirable biological activity and enhances their therapeutic potential. Furthermore, 3-Sulfoalanine has been investigated for its potential use in targeted drug delivery systems and drug conjugates, showcasing its versatility in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
3-Sulfoalanine is a white crystalline powder with no distinct odor. It has a pure appearance and smooth texture.
The molar mass of 3-Sulfoalanine is approximately 195.2 g/mol, and its density is around 1.65 g/cm3. In comparison, common food items like sugar or salt have molar masses in the range of 150-300 g/mol and densities around 1-2 g/cm3.
3-Sulfoalanine has a melting point of around 270°C and a boiling point of approximately 225°C. These values are notably higher than those of common food items, which typically have melting points below 200°C and boiling points around or below 100°C.
3-Sulfoalanine is highly soluble in water and has a low viscosity. This differs from many common food items, which may have lower solubility and higher viscosity in water.
🏭 Production & Procurement
Production of 3-Sulfoalanine typically involves the alkaline hydrolysis of proteins containing sulfur-containing amino acids such as cysteine. This process often takes place under mild conditions to prevent degradation of the amino acid.
Procurement of 3-Sulfoalanine is primarily achieved through chemical synthesis in specialized laboratories. This amino acid derivative is not readily available for purchase due to its limited commercial demand and specific applications.
Transportation of 3-Sulfoalanine usually involves careful handling to prevent degradation or contamination. Due to its chemical nature, this compound may require special packaging and storage conditions to maintain its integrity during transit.
⚠️ Safety Considerations
Safety considerations for 3-Sulfoalanine include its potential to cause skin and eye irritation upon contact. It is important to handle this compound with care by wearing appropriate personal protective equipment such as gloves and safety glasses. In case of accidental exposure, it is recommended to rinse the affected area thoroughly with water and seek medical attention if necessary.
The hazard statements for 3-Sulfoalanine include its ability to cause skin and eye irritation. It is also classified as harmful if swallowed or inhaled. It is important to handle this compound in a well-ventilated area and avoid direct contact with skin or eyes. In case of ingestion or inhalation, seek medical attention immediately.
Precautionary statements for handling 3-Sulfoalanine include wearing appropriate protective clothing and equipment, such as gloves, safety glasses, and a lab coat. It is important to work with this compound in a fume hood to minimize exposure to vapors. Avoid creating aerosols or dust when handling this compound, and wash hands thoroughly after handling. Store 3-Sulfoalanine in a cool, dry place away from incompatible materials, and keep containers tightly closed when not in use.
🔬 Potential Research Directions
One potential research direction for 3-sulfoalanine may involve investigating its potential as a building block for the synthesis of novel peptides with enhanced biological activities. By incorporating 3-sulfoalanine into peptide sequences, researchers may be able to explore its impact on peptide stability and binding affinity to specific targets.
Another promising avenue of research could focus on the development of analytical methods for the detection and quantification of 3-sulfoalanine in biological samples. This could aid in understanding the metabolism and distribution of 3-sulfoalanine in living organisms, as well as its potential role in health and disease.
Furthermore, studying the biosynthesis pathways of 3-sulfoalanine in microorganisms and plants may shed light on its physiological functions and ecological significance. By elucidating the enzymes and metabolic intermediates involved in 3-sulfoalanine production, researchers may uncover new biotechnological applications or environmentally friendly strategies for its production.
🧪 Related Compounds
One similar compound to 3-sulfoalanine based upon molecular structure is 3-Phosphoserine. This compound, like 3-sulfoalanine, contains a sulfur atom and a carboxylic acid group attached to a carbon atom. However, in 3-phosphoserine, the sulfur atom is replaced by a phosphorus atom that is linked to the carbon atom through a double bond.
Another compound with a structure similar to 3-sulfoalanine is 3-Dehydroalanine. This compound also contains a carboxylic acid group attached to a carbon atom, but instead of a sulfur atom, there is a double bond between two carbon atoms. This double bond gives 3-dehydroalanine a different chemical reactivity compared to 3-sulfoalanine.
Furthermore, another compound that shares a similar molecular structure to 3-sulfoalanine is 3-Nitrotyrosine. Like 3-sulfoalanine, this compound contains a carboxylic acid group attached to a carbon atom. However, in 3-nitrotyrosine, a nitro group is attached to the aromatic ring, providing unique chemical properties compared to 3-sulfoalanine.
