3-Pyridinemethanol is a compound that has various applications in everyday life. This chemical is commonly used in the pharmaceutical industry for the synthesis of various drugs, including antihistamines and antidepressants. Additionally, 3-Pyridinemethanol is utilized in the production of certain agrochemicals and insecticides. Its versatile nature and wide range of uses make it an important component in several consumer products and industrial processes.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Pyridinemethanol, also known as nicotinamide, is commonly used in commercial and industrial applications as a precursor in the production of various drugs and pharmaceuticals. It is utilized in the synthesis of Vitamin B3, which is essential for maintaining proper health and functioning of the body. Additionally, 3-Pyridinemethanol is used in the manufacturing of pesticides, dyes, and food additives due to its versatile chemical properties.
In terms of drug and medication applications, 3-Pyridinemethanol plays a crucial role in the treatment of certain skin conditions, such as acne and eczema. Its anti-inflammatory and anti-aging properties make it a common ingredient in topical creams and ointments. Furthermore, nicotinamide has been shown to improve the overall appearance and texture of the skin, making it a popular choice in the cosmetic industry for anti-aging products.
⚗️ Chemical & Physical Properties
3-Pyridinemethanol is a white crystalline solid with a faint odor reminiscent of pyridine. The compound is typically found in a solid state at ambient conditions, and its appearance may vary depending on the purity of the sample.
With a molar mass of approximately 108.1 g/mol and a density of around 1.1 g/cm³, 3-Pyridinemethanol is comparable in molar mass to common food items like glucose and ethanol, but somewhat denser. This suggests the compound has a relatively compact molecular structure compared to these food items.
3-Pyridinemethanol has a melting point of approximately 101-103°C and a boiling point of around 263-264°C. These values are notably higher than those of many common food items, indicating the compound has a relatively high thermal stability compared to substances typically found in a kitchen setting.
The solubility of 3-Pyridinemethanol in water is limited, but it is a moderately viscous liquid at room temperature. In comparison to common food items, its solubility in water is lower than that of salts and sugars, while its viscosity is higher than that of water but lower than that of vegetable oils or honey.
🏭 Production & Procurement
3-Pyridinemethanol, also known as nicotinol, is primarily produced through chemical synthesis. The reaction typically involves the addition of formaldehyde to nicotinic acid, which is then reduced to yield 3-Pyridinemethanol. This method allows for the production of high purity 3-Pyridinemethanol suitable for various industrial applications.
For procuring 3-Pyridinemethanol, manufacturers often rely on chemical suppliers who produce and provide the compound in bulk quantities. The compound is commonly shipped in drums or containers to ensure safe transportation. Due to its stability under normal conditions, 3-Pyridinemethanol can be easily stored and transported without any special precautions.
In addition to chemical suppliers, 3-Pyridinemethanol can also be procured through online chemical marketplaces or through direct contact with manufacturers. These platforms offer a convenient way for researchers, laboratories, and industries to purchase the compound in smaller quantities. The transportation of smaller quantities of 3-Pyridinemethanol is typically done through standard shipping methods, ensuring timely delivery to the end user.
⚠️ Safety Considerations
Safety considerations for 3-Pyridinemethanol, also known as nicotinol, should be taken into account due to its potential hazards. This compound may cause skin irritation and eye irritation upon contact, and inhalation of its vapors can lead to respiratory irritation. It should be handled with caution in order to prevent accidental exposure and ensure a safe working environment.
In terms of hazard statements, 3-Pyridinemethanol is labeled as harmful if swallowed, with potential long-term effects on aquatic life. It is also classified as irritating to the skin and eyes, with the possibility of causing respiratory irritation if inhaled. Proper precautions should be taken to prevent exposure and minimize the risk of adverse effects when working with this compound.
Precautionary statements for 3-Pyridinemethanol include avoiding contact with skin, eyes, and clothing, as well as wearing appropriate protective equipment such as gloves and safety goggles. It is important to work with this compound in a well-ventilated area to prevent inhalation of vapors. Spills should be cleaned up promptly and the compound should be stored in a secure location away from incompatible materials. Adhering to these precautionary measures can help mitigate the risks associated with handling 3-Pyridinemethanol.
🔬 Potential Research Directions
One potential research direction for 3-Pyridinemethanol is its utilization as a precursor in the synthesis of various pharmaceutical compounds. Studies could investigate its reactivity with different functional groups to develop new drug candidates with improved therapeutic properties.
Furthermore, the investigation of the biological activity of 3-Pyridinemethanol and its derivatives is another promising research avenue. This could involve exploring their potential as anti-inflammatory agents, antiviral drugs, or other pharmacologically relevant compounds through in vitro and in vivo studies.
Additionally, the development of novel synthetic methodologies for the efficient production of 3-Pyridinemethanol could be an interesting research focus. This could include exploring alternative catalysts, reaction conditions, or strategies to improve the yield and selectivity of the synthesis process, ultimately leading to more sustainable and cost-effective production methods.
🧪 Related Compounds
One similar compound to 3-Pyridinemethanol is 4-Pyridinemethanol, which has a molecular structure closely resembling that of 3-Pyridinemethanol. In this compound, the hydroxyl group is attached to the fourth carbon atom of the pyridine ring instead of the third, leading to slightly different properties and reactivity.
Another related compound is 2-Pyridinemethanol, where the hydroxyl group is positioned on the second carbon atom of the pyridine ring. This compound exhibits unique characteristics compared to 3-Pyridinemethanol, including differences in solubility, stability, and reactivity due to the altered molecular structure.
Furthermore, N-Methyl-3-pyridinemethanamine is a compound closely related to 3-Pyridinemethanol, differing in the presence of an amino group attached to the nitrogen atom of the pyridine ring. This structural variation leads to distinct chemical properties and interactions, influencing its potential applications and uses in various fields of chemistry and biology.
