3-Phenylpropanamide, often referred to as phenylpropionamide, is a chemical compound commonly used in the pharmaceutical industry as an analgesic and anti-inflammatory agent. Due to its pain-relieving properties, it is frequently found in over-the-counter medications, such as pain relievers and topical creams. This compound plays a crucial role in everyday life by providing relief from a variety of common ailments, such as headaches, muscle aches, and joint pain, thus improving the quality of life for many individuals.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1. 3-Phenylpropanamide, also known as hydrocinnamic acid amide, has a number of commercial and industrial applications. It is commonly used as an intermediate in the production of fragrances, flavors, and pharmaceuticals. Its properties make it a valuable compound in the creation of artificial scents and taste enhancers.
2. In the industrial sector, 3-Phenylpropanamide is utilized in the manufacturing of polymers and plastics. Its ability to act as a stabilizer and antioxidant makes it an essential ingredient in the production of these materials. Its presence can help improve the durability and longevity of various plastic products.
3. Furthermore, 3-Phenylpropanamide is also used in the formulation of cosmetics and personal care products. Its ability to enhance the stability and aroma of these products makes it a popular choice among manufacturers. Its mild yet effective properties make it suitable for a wide range of cosmetic applications.
4. In the realm of medicine, 3-Phenylpropanamide has shown potential as a drug candidate for the treatment of various conditions. It has been studied for its anti-inflammatory and analgesic properties, making it a promising option for pain relief medications. Its ability to modulate immune responses further enhances its potential as a therapeutic agent.
⚗️ Chemical & Physical Properties
3-Phenylpropanamide is a white crystalline solid with a faint odor. It is typically found in a powdered form and has a slight bitter taste when consumed.
The molar mass of 3-Phenylpropanamide is approximately 163.21 g/mol, and its density is around 1.03 g/cm³. This puts it in line with common food items such as table sugar (molar mass: 342.30 g/mol, density: 1.59 g/cm³) and salt (molar mass: 58.44 g/mol, density: 2.17 g/cm³).
The melting point of 3-Phenylpropanamide is around 150-152°C, and its boiling point is approximately 290-295°C. Compared to common food items like butter (melting point: ̴32-35°C, boiling point: ̴177°C) and olive oil (melting point: ̴-6-0°C, boiling point: ̴300°C), 3-Phenylpropanamide has a significantly higher melting and boiling point.
3-Phenylpropanamide is sparingly soluble in water and exhibits low viscosity. This differs from common food items like sugar (high solubility in water) and honey (high viscosity).
🏭 Production & Procurement
3-Phenylpropanamide is typically produced through the reaction between 3-phenylpropionic acid and ammonia. This reaction takes place in the presence of a suitable catalyst under controlled conditions to ensure maximum yield of the desired product. The resulting 3-Phenylpropanamide is then purified through various techniques such as recrystallization or chromatography.
In terms of procurement, 3-Phenylpropanamide can be obtained from various chemical suppliers or manufacturers. It is commonly available in both bulk and smaller quantities, depending on the needs of the customer. The compound can be transported in solid form or as a solution in a solvent, ensuring its stability during transit.
For transportation purposes, 3-Phenylpropanamide is typically packaged in suitable containers to prevent any contamination or degradation during transit. It is important to handle the compound with care and adhere to proper safety protocols when transporting it from one location to another. Furthermore, proper labeling and documentation are essential to ensure compliance with regulations and safety standards.
⚠️ Safety Considerations
Safety considerations for 3-Phenylpropanamide are essential to ensure the proper handling and storage of this chemical compound. It is important to follow standard laboratory safety protocols when working with 3-Phenylpropanamide, including wearing appropriate personal protective equipment such as gloves, goggles, and a lab coat. Additionally, proper ventilation should be in place to prevent inhalation of the compound’s fumes. When storing 3-Phenylpropanamide, it should be kept in a cool, dry place away from heat sources and incompatible materials.
Hazard statements for 3-Phenylpropanamide include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements indicate the potential risks associated with exposure to 3-Phenylpropanamide, highlighting the importance of taking necessary precautions when handling this chemical compound. It is crucial to minimize skin contact, avoid eye contact, and ensure proper ventilation to prevent respiratory issues when working with 3-Phenylpropanamide.
Precautionary statements for 3-Phenylpropanamide include “Wear protective gloves/eye protection/face protection,” “IF ON SKIN: Wash with plenty of water,” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements provide clear guidance on the necessary precautions to take when working with 3-Phenylpropanamide to minimize the risk of exposure and potential harm. By following these precautionary measures, individuals can safely handle 3-Phenylpropanamide and reduce the likelihood of adverse effects.
🔬 Potential Research Directions
Research directions for 3-Phenylpropanamide may include its potential as a precursor in organic synthesis, allowing for the study of new reaction mechanisms and pathways. This compound may also be investigated for its pharmacological properties, particularly its potential as a bioactive molecule in drug discovery. Further research could explore the environmental impact and fate of 3-Phenylpropanamide to assess its potential as a sustainable chemical intermediate.
Studies on the structural modifications of 3-Phenylpropanamide could provide insights into its reactivity and potential applications in various fields such as materials science and medicinal chemistry. Additionally, investigations into the stereochemistry of this compound may offer new perspectives on its biological activity and interactions with other molecules. Furthermore, research on the synthesis of novel derivatives of 3-Phenylpropanamide may lead to the development of new compounds with enhanced properties and functions.
Exploration of the biological activities and potential therapeutic effects of 3-Phenylpropanamide could open up avenues for the development of new pharmaceutical agents for various diseases. Additionally, research on the toxicological profile of this compound could provide valuable information for its safe use in different applications. Investigation into the metabolic fate of 3-Phenylpropanamide in living organisms may shed light on its potential as a prodrug or a metabolic marker for certain physiological conditions.
🧪 Related Compounds
One similar compound to 3-Phenylpropanamide is 3-Methylphenylpropanamide. This compound has a similar molecular structure to 3-Phenylpropanamide, with a methyl group substituted on the phenyl ring. This substitution alters the physical and chemical properties of the compound compared to 3-Phenylpropanamide.
Another similar compound is 3-Ethylphenylpropanamide. In this compound, an ethyl group is attached to the phenyl ring, providing a different chemical environment compared to 3-Phenylpropanamide. This substitution may impact the compound’s reactivity, solubility, and other properties.
Additionally, 3-Isopropylphenylpropanamide is another similar compound. In this molecule, an isopropyl group is attached to the phenyl ring, altering the steric and electronic properties of the compound. This substitution can lead to differences in the compound’s biological activity, stability, and other characteristics.
