3-Oxooctanoyl coenzyme A, a metabolic intermediate in the beta-oxidation pathway of fatty acids, plays a crucial role in energy production within the human body. This molecule is directly involved in breaking down fatty acids to generate ATP, the primary energy source for cellular functions. As such, 3-Oxooctanoyl coenzyme A is essential for everyday activities ranging from basic bodily functions to physical exercise. Understanding its significance can shed light on the complex processes that sustain human life and health.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Oxooctanoyl coenzyme A, also known as 3-oxoacyl-CoA, is a key intermediate molecule in the fatty acid metabolism pathway. In commercial and industrial applications, this compound is utilized in the production of various bioproducts such as biofuels, biopolymers, and specialty chemicals. The enzymatic conversion of 3-oxooctanoyl coenzyme A plays a crucial role in the creation of value-added products derived from renewable resources.
In the realm of drug and medication applications, 3-oxooctanoyl coenzyme A is involved in the synthesis of essential compounds such as ketone bodies, which are crucial energy sources for various tissues including the brain and heart. The dysregulation of this metabolic pathway has been linked to metabolic disorders such as ketosis and mitochondrial diseases. Furthermore, research suggests that modulating the levels of 3-oxooctanoyl coenzyme A could have therapeutic implications in the treatment of metabolic diseases.
⚗️ Chemical & Physical Properties
3-Oxooctanoyl coenzyme A is a white, odorless solid at room temperature. Its crystalline structure gives it a powdery appearance.
The molar mass of 3-Oxooctanoyl coenzyme A is approximately 868.38 g/mol, with a density of about 1.27 g/cm³. This makes it significantly heavier and denser than common food items like sugar and salt.
The melting point of 3-Oxooctanoyl coenzyme A is around 180-185°C, while its boiling point is approximately 434-440°C. These temperatures are much higher compared to common food items, such as butter and olive oil.
3-Oxooctanoyl coenzyme A is insoluble in water and has a high viscosity. Its lack of solubility and thick consistency set it apart from common food items like vinegar and soy sauce.
🏭 Production & Procurement
Producing 3-Oxooctanoyl coenzyme A involves the enzymatic conversion of octanoyl-CoA into 3-Oxooctanoyl coenzyme A. This conversion is catalyzed by the enzyme acyl-CoA dehydrogenase, specifically medium-chain acyl-CoA dehydrogenase (MCAD), within the mitochondria of cells.
3-Oxooctanoyl coenzyme A can be procured by isolating it from biological sources such as mammalian tissues or bacterial cultures. Once obtained, this compound can be transported within the body through the bloodstream to various cellular locations, where it serves as a critical intermediate in fatty acid oxidation pathways.
Due to its unstable nature, 3-Oxooctanoyl coenzyme A is commonly stored and transported in frozen form to preserve its integrity. It can be stored at ultra-low temperatures to prevent degradation and ensure its availability for research and biological studies. Additionally, 3-Oxooctanoyl coenzyme A can be commercially purchased from specialized suppliers for laboratory use.
⚠️ Safety Considerations
Safety considerations for 3-Oxooctanoyl coenzyme A involve handling the compound with caution due to its potential hazards. The substance should be stored in a tightly sealed container away from any sources of ignition. Personal protective equipment, such as gloves and safety goggles, should be worn when handling 3-Oxooctanoyl coenzyme A to prevent skin and eye contact.
When working with 3-Oxooctanoyl coenzyme A, it is important to avoid inhaling the vapors or dust of the compound. Adequate ventilation should be ensured in the working area to prevent the build-up of potentially harmful concentrations of the substance in the air. In case of accidental exposure, immediate medical attention should be sought, and the material safety data sheet for 3-Oxooctanoyl coenzyme A should be consulted for proper handling protocols.
Hazard statements for 3-Oxooctanoyl coenzyme A include warnings about its potential harmful effects on human health and the environment. The compound may cause skin and eye irritation upon contact, and inhalation of its vapors or dust may lead to respiratory irritation. Ingestion of 3-Oxooctanoyl coenzyme A should be avoided as it can cause gastrointestinal irritation and other adverse effects.
Precautionary statements for 3-Oxooctanoyl coenzyme A emphasize the importance of following safe handling practices to minimize risks. Avoid direct skin and eye contact with the compound, and wash hands thoroughly after handling to prevent accidental ingestion. Store the substance in a cool, dry place away from incompatible materials, and dispose of it according to local regulations to prevent environmental contamination. Safety data sheets for 3-Oxooctanoyl coenzyme A should be consulted for specific guidance on safe handling procedures.
🔬 Potential Research Directions
One potential research direction for 3-Oxooctanoyl coenzyme A involves studying its role in various metabolic pathways, such as fatty acid oxidation and ketogenesis. Understanding the precise mechanisms by which this molecule participates in these processes could provide insights into metabolic diseases and potential therapeutic targets.
Another area of interest could be exploring the interactions of 3-Oxooctanoyl coenzyme A with other enzymes and molecules in the cell. Investigating how this molecule regulates or is regulated by other metabolic pathways could shed light on its broader physiological significance and metabolic network connectivity.
Furthermore, investigating the role of 3-Oxooctanoyl coenzyme A in different tissues and cell types could provide valuable information on its biological functions and its implications in health and disease. Studying the tissue-specific expression patterns and regulatory mechanisms of this molecule may uncover novel pathways and targets for therapeutic intervention.
🧪 Related Compounds
One similar compound to 3-Oxooctanoyl coenzyme A based upon molecular structure is 3-Oxodecanoyl coenzyme A. This molecule is structurally similar to 3-Oxooctanoyl coenzyme A, but with a longer carbon chain of ten carbons.
Another similar compound is 3-Oxohexanoyl coenzyme A, which has a shorter carbon chain of six carbons compared to 3-Oxooctanoyl coenzyme A. Despite the difference in chain length, both compounds share the same 3-oxo moiety.
Additionally, 3-Oxopentanoyl coenzyme A is another compound that bears resemblance to 3-Oxooctanoyl coenzyme A. This molecule has a shorter carbon chain of five carbons and also features the 3-oxo functional group found in 3-Oxooctanoyl coenzyme A.
