3-Nitrobenzotrifluoride is a chemical compound that has relevance in everyday life due to its use in the production of pharmaceuticals, agrochemicals, and specialty materials. This compound is a key building block in the synthesis of various organic compounds, which are used in a wide range of applications, from medicine to agriculture. Its unique properties make it a valuable component in the creation of products that impact our daily lives, such as medications, pesticides, and advanced materials. Its versatility and importance in various industries highlight the significance of 3-Nitrobenzotrifluoride in our everyday lives.
Table of Contents:
Commercial Applications
Chemical & Physical Properties
Production & Procurement
Safety Considerations
Potential Research Directions
Related Compounds
Commercial Applications
3-Nitrobenzotrifluoride, also known as 3-Nitrobenzotrifluoride, is a chemical compound with a variety of commercial and industrial applications. It is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. Due to its high reactivity, 3-Nitrobenzotrifluoride is also utilized in organic synthesis for the creation of a wide range of compounds. Additionally, it can be employed as a building block in the manufacturing of specialty chemicals and polymers.
In terms of drug and medication applications, 3-Nitrobenzotrifluoride plays a crucial role in the pharmaceutical industry. It is utilized in the synthesis of various drug molecules, particularly those with fluorinated structures. This compound’s unique properties make it an essential component in the creation of fluorinated pharmaceuticals, which are used in the treatment of a variety of diseases and conditions. Due to its versatility and effectiveness, 3-Nitrobenzotrifluoride holds great importance in the development of cutting-edge medications and therapies.
Chemical & Physical Properties
3-Nitrobenzotrifluoride is a pale yellow solid with a faint odor. It appears as fine crystals with a melting point of 29-31°C.
The molar mass of 3-Nitrobenzotrifluoride is 201.11 g/mol and its density is 1.491 g/cm3. Compared to common food items such as sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm3) and table salt (molar mass: 58.44 g/mol, density: 2.165 g/cm3), 3-Nitrobenzotrifluoride has a lower molar mass but a similar density.
3-Nitrobenzotrifluoride has a melting point of 29-31°C and a boiling point of 152-154°C. In comparison, common food items such as butter (melting point: 32-35°C, boiling point: > 200°C) and chocolate (melting point: 34-38°C, boiling point: > 200°C) have higher melting and boiling points.
3-Nitrobenzotrifluoride is sparingly soluble in water and has a low viscosity. Compared to common food items like sugar (very soluble in water, low viscosity) and olive oil (insoluble in water, moderate viscosity), 3-Nitrobenzotrifluoride has poor solubility in water and a lower viscosity.
Production & Procurement
3-Nitrobenzotrifluoride, a compound with the chemical formula C7H4F3NO2, is typically produced through a nitration reaction involving the reaction of 3-nitro-fluorobenzene with sulfuric acid and nitric acid as the nitrating agents. This reaction leads to the substitution of a nitro group at the desired position on the benzene ring, resulting in the formation of 3-Nitrobenzotrifluoride.
Once produced, 3-Nitrobenzotrifluoride can be procured through chemical suppliers or manufacturers who specialize in the production and distribution of fine chemicals and specialty materials. It is often transported in sealed containers to prevent exposure to moisture and other reactive substances that may degrade the compound during transit. Proper labeling and handling procedures are typically followed to ensure safe transportation and storage.
The procurement of 3-Nitrobenzotrifluoride may involve strict adherence to regulatory guidelines and safety precautions due to its potentially hazardous nature. Specialized equipment and protocols may be necessary for handling and storing the compound to minimize risks associated with its use. Careful documentation of procurement activities and tracking of inventory levels are essential to ensure the safe and efficient handling of 3-Nitrobenzotrifluoride in industrial and research settings.
Safety Considerations
Safety considerations for 3-Nitrobenzotrifluoride include its potential hazards when exposed to heat, flames, or incompatible materials. It is essential to handle this compound with proper protective equipment, such as gloves, safety goggles, and a lab coat, to prevent skin contact, eye irritation, or inhalation of vapors. Additionally, it is important to store 3-Nitrobenzotrifluoride in a cool, well-ventilated area away from sources of ignition to minimize the risk of fire or explosion.
Hazard statements for 3-Nitrobenzotrifluoride include its ability to cause skin and eye irritation upon contact, as well as respiratory irritation if inhaled. This compound may also be harmful if swallowed or absorbed through the skin, leading to potential health risks. Furthermore, exposure to 3-Nitrobenzotrifluoride may result in allergic skin reactions and damage to organs through prolonged or repeated exposure.
Precautionary statements for 3-Nitrobenzotrifluoride recommend avoiding skin, eye, and clothing contact with the compound to minimize the risk of irritation or harm. It is crucial to use this chemical in a well-ventilated area, preferably under a fume hood, to prevent inhalation of vapors. In case of accidental exposure or ingestion, seek medical advice immediately and provide the SDS (Safety Data Sheet) for proper treatment guidance. Additionally, store 3-Nitrobenzotrifluoride in a tightly closed container away from heat, sparks, or flames to prevent fire hazards.
Potential Research Directions
Research on 3-Nitrobenzotrifluoride has shown its potential as a precursor in the synthesis of various organic compounds. Further studies could explore its reactivity in different reaction conditions and its potential applications in organic chemistry.
Investigations into the reactivity of 3-Nitrobenzotrifluoride with different nucleophiles could provide valuable insights into its synthetic utility. Understanding the mechanisms of these reactions could aid in the development of new synthetic methodologies for accessing complex molecules.
Exploration of the potential biological activities of 3-Nitrobenzotrifluoride and its derivatives could uncover new therapeutic agents. Studying the interactions of these compounds with biological targets could lead to the development of new drugs with improved potency and selectivity.
Related Compounds
One similar compound to 3-Nitrobenzotrifluoride based on molecular structure is 4-Nitrobenzotrifluoride. In this compound, the nitro group is located at the para position on the benzene ring, similar to the positioning of the nitro group in 3-Nitrobenzotrifluoride. This similarity in the positioning of the nitro group results in similar chemical properties between the two compounds.
Another similar compound to 3-Nitrobenzotrifluoride is 2-Nitrobenzotrifluoride. In this compound, the nitro group is located at the ortho position on the benzene ring. While the positioning of the nitro group differs from that of 3-Nitrobenzotrifluoride, the presence of the nitro group results in similar reactivity and properties between the two compounds. Additionally, both compounds contain trifluoromethyl groups attached to the benzene ring, further enhancing their similarity.
A third similar compound to 3-Nitrobenzotrifluoride is Nitrobenzotrifluoride. This compound lacks the trifluoromethyl groups found in 3-Nitrobenzotrifluoride, but shares the same nitrobenzene structure. Despite the absence of trifluoromethyl groups, Nitrobenzotrifluoride exhibits similar reactivity and chemical properties to 3-Nitrobenzotrifluoride due to the presence of the nitro group on the benzene ring.
