3-Nitrobenzamide is a compound commonly used in organic chemistry research and pharmaceutical development. It has been shown to possess antibacterial and anti-inflammatory properties, making it a crucial component in the creation of various medications. In everyday life, this compound may play a role in the development of new drugs that could potentially treat a wide range of medical conditions, thus impacting the health and well-being of individuals worldwide.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Nitrobenzamide, a chemical compound belonging to the class of aromatic amides, finds various commercial and industrial applications. It is utilized in organic synthesis as a starting material for the preparation of various pharmaceutical compounds and dyes. Additionally, it is utilized in the manufacturing of pesticides and other agricultural chemicals due to its chemical structure and properties.
In terms of drug and medication applications, 3-Nitrobenzamide is widely used in the pharmaceutical industry for the synthesis of other compounds with therapeutic properties. It serves as a key intermediate in the production of certain drugs, particularly those used in the treatment of neurological disorders and cancer. Its ability to undergo various chemical reactions makes it a valuable building block in drug discovery and development.
Furthermore, 3-Nitrobenzamide exhibits potential as a chelating agent in certain biomedical applications. Its ability to bind and remove heavy metals from biological systems has sparked interest in its use in chelation therapy for the treatment of metal poisoning. This property, along with its chemical versatility, positions 3-Nitrobenzamide as a valuable tool in both industrial and pharmaceutical settings.
⚗️ Chemical & Physical Properties
3-Nitrobenzamide is a white crystalline solid with a slight odor, which is commonly described as faint and not easily discernible by the human nose. The compound is typically found in the form of fine powder particles.
The molar mass of 3-Nitrobenzamide is 152.13 g/mol, and its density is approximately 1.31 g/cm³. This puts it in the range of common food items such as sugars and salts in terms of molar mass and density, making it comparable to everyday substances found in the kitchen.
The melting point of 3-Nitrobenzamide is around 162-164°C, while the boiling point is approximately 329°C. These values are significantly higher than those of typical food items, which generally melt and boil at much lower temperatures, indicating the compound’s higher stability and resistance to heat.
3-Nitrobenzamide is sparingly soluble in water, and it has low viscosity. This contrasts with many food items, which are often highly soluble in water and have varying viscosities. This difference in solubility and viscosity can be attributed to the compound’s chemical structure and interactions with the solvent.
🏭 Production & Procurement
3-Nitrobenzamide is produced through the nitration reaction of benzamide with a mixture of nitric acid and sulfuric acid. The reaction typically takes place under controlled conditions, ensuring the formation of the desired product.
3-Nitrobenzamide can be procured from various chemical suppliers specializing in aromatic compounds. The product is typically available in a solid form, packaged in appropriate containers to prevent degradation or contamination during transport.
When procuring 3-Nitrobenzamide, it is essential to ensure compliance with transportation regulations for hazardous chemicals. Depending on the quantity and destination, special handling and labeling may be required to ensure the safe and secure transportation of the product.
⚠️ Safety Considerations
Safety Considerations for 3-Nitrobenzamide:
When handling 3-Nitrobenzamide, it is important to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat to prevent skin and eye contact. The compound should be stored in a cool, dry, well-ventilated area away from incompatible substances.
It is crucial to avoid ingestion, inhalation, or contact with skin or eyes when working with 3-Nitrobenzamide. In case of exposure, rinse the affected area with plenty of water and seek medical attention if necessary. Proper disposal methods should be followed to prevent environmental contamination.
Precautions should be taken to avoid any potential sources of ignition or heat that could cause 3-Nitrobenzamide to decompose or ignite. It is also important to thoroughly wash hands after handling the compound and to avoid eating, drinking, or smoking in the lab area to prevent accidental exposure. Following these safety considerations will help minimize the risks associated with working with 3-Nitrobenzamide.
Summary of Hazard Statements for 3-Nitrobenzamide:
3-Nitrobenzamide is classified as harmful if swallowed, inhaled, or in contact with skin. It may cause irritation to the respiratory system, skin, and eyes. The compound is also considered harmful to aquatic organisms and can cause long-term adverse effects in the aquatic environment.
Summary of Precautionary Statements for 3-Nitrobenzamide:
Precautionary measures include wearing appropriate personal protective equipment, avoiding contact with eyes, skin, and clothing, and ensuring adequate ventilation when working with 3-Nitrobenzamide. It is important to keep the compound away from sources of ignition and heat, and to wash hands thoroughly after handling. Proper disposal methods should be followed to prevent environmental contamination.
🔬 Potential Research Directions
One potential research direction for 3-Nitrobenzamide lies in its use as a building block for the synthesis of various pharmaceutical compounds due to its versatile chemical structure and potential pharmacological activities. Further investigations may focus on exploring its potential anti-cancer properties and its ability to inhibit specific targets in cancer cells.
Studies on the environmental impact of 3-Nitrobenzamide may also be of interest, as this compound has the potential to degrade into harmful byproducts in soil and water systems. Research in this area can help in understanding the ecological consequences of its presence in the environment and develop strategies for mitigating its impact.
Exploring the mechanisms of action of 3-Nitrobenzamide at a molecular level could provide valuable insights into its biological activity and therapeutic potential. Investigating its interactions with specific molecular targets and pathways may shed light on its potential applications in drug development and treatment of various diseases.
🧪 Related Compounds
One similar compound to 3-Nitrobenzamide based upon molecular structure is 4-Nitrobenzamide. In this compound, the nitro group is attached to the benzene ring at the 4-position, rather than the 3-position as in 3-Nitrobenzamide. This slight change in positioning of the nitro group can lead to differences in reactivity and biological activity.
Another related compound is Nitroacetanilide, which shares a similar molecular structure with 3-Nitrobenzamide. In this compound, the nitro group is connected to an aniline group by an acetamido linker. This substitution of the benzene ring with an aniline group results in different chemical properties compared to 3-Nitrobenzamide.
Furthermore, 3-Nitroacetophenone is another compound that bears resemblance to 3-Nitrobenzamide in terms of molecular structure. In this compound, the nitro group is attached to a phenyl ring, similar to the benzene ring in 3-Nitrobenzamide. However, the presence of a ketone group in 3-Nitroacetophenone distinguishes it from 3-Nitrobenzamide and imparts distinct chemical reactivity and properties.
