3-Nitrobenzaldehyde is a chemical compound that is commonly used in the pharmaceutical industry for the synthesis of various drugs and medications. It is also utilized in the production of dyes, pigments, and fragrances. Additionally, 3-Nitrobenzaldehyde is a key component in the manufacturing of pesticides and insecticides, which are essential for protecting crops and controlling insect populations. Overall, this compound plays a crucial role in everyday life by contributing to the development of essential products that impact various aspects of society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Nitrobenzaldehyde, also known as m-Nitrobenzaldehyde, possesses various commercial and industrial applications. This compound is commonly utilized in the production of dyes, perfumes, and agricultural chemicals. Additionally, 3-Nitrobenzaldehyde is a key intermediate in the synthesis of pharmaceuticals and organic compounds.
In terms of drug and medication applications, 3-Nitrobenzaldehyde plays a crucial role in the pharmaceutical industry. It is utilized as a building block for the synthesis of numerous medications, including anti-inflammatories, antifungals, and antibacterials. Moreover, this compound is also employed in the development of specific pharmaceutical intermediates for various drugs.
Furthermore, 3-Nitrobenzaldehyde exhibits potential applications in the field of medicine for research purposes. Due to its versatile chemical properties, this compound is utilized in the creation of novel drug molecules and formulations for clinical studies. Researchers continue to explore the beneficial properties of 3-Nitrobenzaldehyde for potential therapeutic uses in the future.
⚗️ Chemical & Physical Properties
3-Nitrobenzaldehyde is a pale yellow solid with a distinct almond-like odor. It is commonly used as an intermediate in the synthesis of pharmaceuticals and dyes due to its aromatic properties and reactivity.
The molar mass of 3-Nitrobenzaldehyde is approximately 151.13 g/mol, with a density of about 1.32 g/cm³. Compared to common food items like sugar (molar mass of 342.3 g/mol and density of 1.59 g/cm³), 3-Nitrobenzaldehyde has a lower molar mass and density.
The melting point of 3-Nitrobenzaldehyde is around 107-110°C, while the boiling point is approximately 295-300°C. In comparison, common food items like butter (melting point of 32-35°C) and water (boiling point of 100°C) have significantly lower melting and boiling points.
3-Nitrobenzaldehyde has limited solubility in water but is miscible with organic solvents like ethanol. It also exhibits a relatively low viscosity. Compared to common food items like salt (high solubility in water) and honey (high viscosity), 3-Nitrobenzaldehyde shows different properties in terms of solubility and viscosity.
🏭 Production & Procurement
3-Nitrobenzaldehyde is typically produced through a process known as nitration, in which nitric acid reacts with benzaldehyde, resulting in the substitution of a hydrogen atom with a nitro group at the meta position. This reaction is typically carried out using a mixture of nitric acid and sulfuric acid as a nitrating agent.
Once produced, 3-Nitrobenzaldehyde can be procured through chemical suppliers who specialize in fine chemicals and intermediates. The compound is often available in liquid form or as a crystalline solid, depending on the supplier. Due to its hazardous nature, proper handling and transportation protocols must be adhered to in order to ensure safety.
When procured, 3-Nitrobenzaldehyde is typically transported in sealed containers to prevent leakage or spills during transit. The compound is classified as a hazardous material, requiring compliance with regulations set forth by local authorities and international transportation standards. Suppliers typically utilize specialized carriers with training in handling hazardous substances to ensure safe delivery to the end user.
⚠️ Safety Considerations
Safety considerations for handling 3-Nitrobenzaldehyde include its flammable nature, as it can ignite if exposed to heat or open flames. Additionally, this chemical is harmful if swallowed, inhaled, or absorbed through the skin. Proper personal protective equipment should be worn when working with 3-Nitrobenzaldehyde, including gloves, goggles, and a lab coat. It is essential to work in a well-ventilated area or use a fume hood to prevent exposure to potentially harmful vapors.
The hazard statements for 3-Nitrobenzaldehyde include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements emphasize the potential risks associated with direct contact with the compound and the importance of using appropriate protective measures when handling it. It is crucial to heed these hazard warnings to prevent harm to oneself or others in the laboratory or workplace.
Precautionary statements for 3-Nitrobenzaldehyde include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements highlight the importance of wearing appropriate personal protective equipment to minimize the risk of exposure to this chemical. Responding promptly to accidental exposure by rinsing affected areas with water is crucial in cases of eye contact to prevent further harm. It is crucial to follow these precautionary statements to ensure safe handling and minimize the risk of accidents or injuries.
🔬 Potential Research Directions
One potential research direction for 3-Nitrobenzaldehyde is the investigation of its use as a building block in organic synthesis. By studying the reactivity of this compound with various nucleophiles and electrophiles, researchers can explore new pathways for the synthesis of complex organic molecules.
Another prospective research avenue is the examination of the properties of 3-Nitrobenzaldehyde as a potential drug precursor. Its unique structure and potential pharmacological activities make it an interesting candidate for the development of novel therapeutic agents. Further studies could elucidate its potential as a lead compound in drug discovery.
Additionally, researchers may focus on the environmental impact of 3-Nitrobenzaldehyde and develop strategies for its sustainable production and disposal. Understanding the chemical behavior and toxicity of this compound in the environment could lead to the implementation of environmentally friendly practices in its synthesis and usage. By exploring these research directions, scientists can contribute to the advancement of knowledge in organic chemistry and chemical engineering.
🧪 Related Compounds
One similar compound to 3-Nitrobenzaldehyde based upon molecular structure is 4-Nitrobenzaldehyde. This compound is structurally similar to 3-Nitrobenzaldehyde, with a nitro group attached to the benzene ring at the para position. Like 3-Nitrobenzaldehyde, 4-Nitrobenzaldehyde is commonly used in organic synthesis as a building block for various chemical reactions.
Another similar compound to 3-Nitrobenzaldehyde is 2-Nitrobenzaldehyde. This compound also possesses a nitro group attached to the benzene ring, but at the ortho position. 2-Nitrobenzaldehyde shares similar chemical properties with 3-Nitrobenzaldehyde due to their structural resemblance, making it useful in similar applications in organic chemistry.
Additionally, a related compound to 3-Nitrobenzaldehyde is Nitrobenzaldehyde. This compound is the parent compound without any specific substitution on the benzene ring. Nitrobenzaldehyde can undergo various chemical reactions to introduce different functional groups at different positions on the benzene ring, allowing for a diverse array of derivatives to be synthesized. This compound serves as the basis for the synthesis of other nitrobenzaldehyde derivatives, such as 3-Nitrobenzaldehyde.
