3-Iodoaniline is a chemical compound that has a significant impact on various aspects of everyday life. This compound is commonly used in the pharmaceutical industry for the synthesis of important drugs and medications. Additionally, 3-Iodoaniline is utilized in the manufacturing of dyes, pigments, and other chemicals that are essential in various industries. Its importance lies in its versatility and ability to be tailored for different applications, ultimately contributing to the development of numerous products that are essential for modern society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Iodoaniline, a compound with the chemical formula C6H6IN, has various commercial and industrial applications. It is primarily used as a precursor in the synthesis of pharmaceuticals, dyes, agrochemicals, and other specialty chemicals. Furthermore, 3-Iodoaniline is employed as an intermediate in the production of optical brighteners and UV stabilizers for polymers and textiles.
In terms of drug and medication applications, 3-Iodoaniline is utilized in the synthesis of various pharmaceuticals. It serves as a key building block in the production of antibacterial agents, antiviral drugs, and antifungal medications. Additionally, 3-Iodoaniline is used in the development of imaging agents for medical diagnostics, demonstrating its significance in the healthcare industry. Its versatility and reactivity make it a valuable compound in drug discovery and development processes.
⚗️ Chemical & Physical Properties
3-Iodoaniline is a white to pale yellow crystalline solid with a faint odor. It is sparingly soluble in water but soluble in organic solvents such as ethanol and acetone.
The molar mass of 3-Iodoaniline is approximately 219.04 g/mol, with a density of about 1.74 g/cm3. By comparison, common food items such as sugar and salt have molar masses ranging from 342.30 g/mol to 58.44 g/mol and densities ranging from 1.59 g/cm3 to 2.16 g/cm3.
3-Iodoaniline has a melting point of around 63-65°C and a boiling point of approximately 288-291°C. In contrast, common food items such as butter and chocolate have melting points ranging from 30-37°C and 30-33°C, respectively, and boiling points above 100°C.
3-Iodoaniline is minimally soluble in water but is viscous, forming a thick liquid at room temperature. In comparison, common food items like honey and corn syrup are highly soluble in water and have similar viscosities to 3-Iodoaniline.
🏭 Production & Procurement
3-Iodoaniline, also known as m-iodoaniline, is typically produced through the reaction of aniline with iodine in the presence of acid. This reaction results in the substitution of the hydrogen in the aniline molecule with an iodine atom at the meta position, thus forming 3-Iodoaniline.
In terms of procurement, 3-Iodoaniline can be obtained from chemical suppliers specializing in aromatic compounds. It is commonly available in various purities and quantities to suit the needs of researchers and industrial applications. Due to its chemical nature, 3-Iodoaniline is usually transported in sealed containers to prevent any potential reactions or contamination during transit.
For transportation, 3-Iodoaniline is often shipped in compliance with international regulations governing the transportation of hazardous chemicals. Proper labeling and packaging are essential to ensure the safe handling and delivery of this compound to its destination. Additionally, precautions such as temperature control may be necessary to prevent degradation or unwanted reactions en route.
⚠️ Safety Considerations
Safety considerations for 3-Iodoaniline include its potential to cause skin and eye irritation upon contact. It is also a flammable liquid and should be stored away from sources of ignition. Proper personal protective equipment should be worn when handling this compound, including gloves, goggles, and lab coat. Additionally, 3-Iodoaniline should be used in a well-ventilated area to avoid inhalation of vapors.
Hazard statements for 3-Iodoaniline include “causes skin and eye irritation” and “may be harmful if swallowed.” It is also classified as a flammable liquid and can form explosive peroxides when exposed to air. This compound should be kept away from heat, sparks, and open flames to prevent accidents.
Precautionary statements for 3-Iodolamine include wearing protective gloves, clothing, eye protection, and face protection when handling this compound. It should be kept away from heat, sparks, open flames, and hot surfaces. Avoid breathing in vapors or mist, and wash thoroughly after handling. In case of fire, use dry chemical, CO2, water spray, or foam for extinguishing.
🔬 Potential Research Directions
Potential research directions for 3-Iodoaniline include its use as a building block in the synthesis of various biologically active compounds. Additionally, further investigation into the reactivity of 3-Iodoaniline in different chemical reactions could provide insight into its potential applications in pharmaceuticals and materials science.
Exploring the catalytic properties of 3-Iodoaniline in various reactions could lead to the development of novel methodologies for efficient and selective functionalization of organic molecules. Moreover, studying the behavior of 3-Iodoaniline under different reaction conditions may reveal new reaction pathways and enhance its synthetic utility in organic chemistry.
Investigating the toxicological properties of 3-Iodoaniline and its potential environmental impact is another important research direction. Understanding the fate and transport of 3-Iodoaniline in the environment could help in assessing its potential risks and developing strategies for its safe handling and disposal.
🧪 Related Compounds
One similar compound to 3-Iodoaniline based upon molecular structure is 4-Iodoaniline. This compound also contains an aniline group (C6H5NH2) substituted with an iodine atom at the para position (4-position) on the benzene ring. 4-Iodoaniline shares the same general structure as 3-Iodoaniline but differs in the position of the iodine atom on the benzene ring.
Another similar compound to 3-Iodoaniline is 2-Iodoaniline. This compound contains an aniline group substituted with an iodine atom at the meta position (2-position) on the benzene ring. Like 3-Iodoaniline, 2-Iodoaniline also exhibits aromatic properties due to the conjugated pi-electron system in the benzene ring. The difference in position of the iodine atom on the benzene ring distinguishes 2-Iodoaniline from 3-Iodoaniline.
Furthermore, N-Iodoaniline is another compound that shares similarities with 3-Iodoaniline based on molecular structure. In N-Iodoaniline, the iodine atom is attached to the amino nitrogen atom of the aniline group. This structural modification results in subtle differences in chemical reactivity and physical properties compared to 3-Iodoaniline. The presence of the iodine atom at the nitrogen of the aniline group distinguishes N-Iodoaniline from its positional isomer, 3-Iodoaniline.
