3-Hydroxypyridine is a compound that serves a variety of important functions in everyday life. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical products. Additionally, 3-Hydroxypyridine has applications in the agricultural sector as an intermediate for the production of herbicides and pesticides. Furthermore, it is utilized in the production of agrochemicals and as a reagent in organic synthesis. Overall, 3-Hydroxypyridine plays a crucial role in both the healthcare and agricultural industries, making it a relevant and significant compound in everyday life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Hydroxypyridine, also known as 3-Pyridinol, has various commercial and industrial applications. It is used as a building block in the production of pharmaceuticals, agrochemicals, and dyes. In addition, it is utilized in the synthesis of pesticides and rubber chemicals.
In the realm of drug and medication applications, 3-Hydroxypyridine is commonly used as an intermediate in the synthesis of active pharmaceutical ingredients. It is employed in the manufacturing of drugs for the treatment of cardiovascular diseases, neurological disorders, and microbial infections. Furthermore, 3-Hydroxypyridine plays a crucial role in the production of antifungal and anti-inflammatory medications.
⚗️ Chemical & Physical Properties
3-Hydroxypyridine is a colorless liquid with a strong, unpleasant odor resembling that of pyridine. It is a heterocyclic compound with the chemical formula C5H5NO, containing a hydroxyl group attached to the pyridine ring.
The molar mass of 3-Hydroxypyridine is approximately 95.1 g/mol, while its density is around 1.1 g/cm3. Compared to common food items such as sugar (180.16 g/mol) and water (1 g/cm3), 3-Hydroxypyridine has a lower molar mass and higher density.
3-Hydroxypyridine has a melting point of 40°C and a boiling point of 230°C. These values are higher than those of common food items like salt (melting point: 801°C) and milk (boiling point: 100°C). This indicates that 3-Hydroxypyridine is more volatile and requires higher temperatures to change its state.
3-Hydroxypyridine is soluble in water and exhibits low viscosity. Compared to common food items like sugar (soluble) and honey (viscous), 3-Hydroxypyridine has similar solubility but lower viscosity. This makes it easier to dissolve in water but less resistant to flow.
🏭 Production & Procurement
3-Hydroxypyridine is produced through a series of chemical reactions involving pyridine as the starting material. The process typically involves the addition of a hydroxyl group to the pyridine ring, resulting in the formation of 3-Hydroxypyridine as the desired product. Various catalysts and reaction conditions may be employed to facilitate the conversion.
The procurement of 3-Hydroxypyridine can be achieved through several means. One common method is the purchase of commercially available quantities from chemical suppliers that specialize in fine chemicals and intermediates. Alternatively, it can be synthesized in-house using the appropriate equipment and expertise. Once obtained, 3-Hydroxypyridine can be stored and transported in suitable containers to ensure its stability and purity during transit.
Transporting 3-Hydroxypyridine typically involves handling the compound with care due to its potentially hazardous nature. Specialized containers, such as glass bottles or plastic drums, may be used to ensure the integrity of the product during transportation. Additionally, adherence to relevant safety regulations and guidelines is essential to prevent any incidents or accidents during the shipment of 3-Hydroxypyridine.
⚠️ Safety Considerations
Safety considerations for 3-Hydroxypyridine include its potential to cause skin and eye irritation, as well as respiratory irritation if inhaled. It is important to handle this chemical with caution in order to avoid any potential harm. Proper personal protective equipment, such as gloves and goggles, should be worn when working with 3-Hydroxypyridine to minimize the risk of exposure.
Hazard statements for 3-Hydroxypyridine include “Causes skin and eye irritation” and “May cause respiratory irritation.” These statements indicate the potential harmful effects of this chemical on human health. It is important to take appropriate precautions when handling 3-Hydroxypyridine to avoid any adverse effects.
Precautionary statements for 3-Hydroxypyridine include “Wear protective gloves/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements provide guidance on how to safely handle and use 3-Hydroxypyridine in order to minimize the risk of exposure and prevent any harm. It is important to follow these precautions to ensure the safe usage of this chemical.
🔬 Potential Research Directions
One potential research direction for 3-Hydroxypyridine includes its pharmacological properties, particularly its potential as a therapeutic agent for various medical conditions. Studies could explore its mechanisms of action, bioavailability, and potential drug interactions.
Another area of interest for research on 3-Hydroxypyridine is its role in environmental chemistry and toxicology. Investigations could focus on its presence in water sources, soil, and air, as well as its potential impact on human and environmental health. Additionally, studies could examine methods for monitoring and removing 3-Hydroxypyridine from the environment.
Further research could delve into the synthesis and structure-activity relationships of 3-Hydroxypyridine derivatives. By investigating different functional groups and modifications on the pyridine ring, researchers may uncover new compounds with improved bioactivity and selectivity. This line of inquiry could lead to the development of novel pharmaceuticals or agrochemicals with enhanced efficacy and safety profiles.
🧪 Related Compounds
One similar compound to 3-Hydroxypyridine based upon molecular structure is 2-Hydroxypyridine. Also known as 2-pyridinol, this compound has a hydroxyl group attached to the second carbon atom of the pyridine ring. This structural similarity allows 2-Hydroxypyridine to participate in similar chemical reactions and biological processes as 3-Hydroxypyridine.
Another similar compound to 3-Hydroxypyridine is 4-Hydroxypyridine. Commonly referred to as 4-pyridinol, this compound features a hydroxyl group attached to the fourth carbon atom of the pyridine ring. Like 3-Hydroxypyridine, 4-Hydroxypyridine exhibits similar chemical reactivity due to the presence of the hydroxyl group in its molecular structure.
Additionally, another compound with a comparable structure to 3-Hydroxypyridine is 2,3-Dihydroxypyridine. In this compound, there are two hydroxyl groups attached to the second and third carbon atoms of the pyridine ring. This structural feature results in unique chemical properties and reactivity, distinguishing it from both 2-Hydroxypyridine and 4-Hydroxypyridine.
