3-Hydroxy-3-methyloxindole, also known as 3-HMO, is a compound that has garnered attention for its potential role in health and disease. Research suggests that 3-HMO may play a significant role in regulating gut health, metabolism, and immunity. Therefore, understanding the functions and mechanisms of 3-HMO could provide valuable insights into maintaining and improving overall well-being. This compound has the potential to impact daily life by influencing various aspects of human health and may lead to the development of novel therapeutic interventions in the future.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Hydroxy-3-methyloxindole, also known as isatin, is a versatile compound with various commercial and industrial applications. One of its primary uses is as a precursor in the synthesis of dyes, particularly indigo dyes, due to its ability to react with amines and aldehydes to produce colored compounds. Additionally, 3-Hydroxy-3-methyloxindole is utilized in the production of pharmaceuticals and agrochemicals.
In the realm of drug and medication applications, 3-Hydroxy-3-methyloxindole has shown potential as a biological activity modifier in the development of therapeutics. Researchers have explored its anti-inflammatory and antimicrobial properties for possible use in pharmaceutical formulations. Furthermore, studies have indicated that 3-Hydroxy-3-methyloxindole may have neuroprotective effects, making it a subject of interest for drug discovery in the treatment of neurodegenerative diseases.
⚗️ Chemical & Physical Properties
3-Hydroxy-3-methyloxindole is a white solid compound that has no distinct odor when in pure form. It is commonly found in the synthesis of various pharmaceuticals due to its properties and structure.
The molar mass of 3-Hydroxy-3-methyloxindole is approximately 179.19 g/mol, with a density of 1.37 g/cm³. Compared to common food items, such as water with a molar mass of 18.02 g/mol and a density of 1.00 g/cm³, 3-Hydroxy-3-methyloxindole is heavier and more dense.
The melting point of 3-Hydroxy-3-methyloxindole is around 149-150°C, with a boiling point of approximately 361°C. When compared to common food items like sugar with a melting point of 186°C and a boiling point above 300°C, 3-Hydroxy-3-methyloxindole has a lower melting point but a higher boiling point.
3-Hydroxy-3-methyloxindole is sparingly soluble in water, with a low viscosity. In comparison to common food items like salt, which has high solubility in water and low viscosity, 3-Hydroxy-3-methyloxindole exhibits lower solubility and viscosity.
🏭 Production & Procurement
3-Hydroxy-3-methyloxindole is typically produced through a multi-step chemical synthesis process involving various reagents and catalysts. This synthesis route usually begins with the reaction of an appropriate indole derivative with a specific alkylating agent to introduce the desired methyl group at the C-3 position. Subsequent oxidation steps lead to the formation of the hydroxyl group at the C-3 position, resulting in the final product of 3-Hydroxy-3-methyloxindole.
The procurement of 3-Hydroxy-3-methyloxindole can be carried out through specialized chemical suppliers or custom synthesis services. Once produced, the compound can be transported in solid form or dissolved in a suitable solvent depending on its stability and handling requirements. Proper packaging and labeling are essential to ensure the safe handling and transport of 3-Hydroxy-3-methyloxindole to its intended destination.
Upon procurement, 3-Hydroxy-3-methyloxindole should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability and purity. Proper documentation, including safety data sheets and certificates of analysis, should be provided with the compound to ensure compliance with regulatory requirements and facilitate its use in research or industrial applications. Any handling or storage guidelines recommended by the supplier should be followed to ensure the integrity and efficacy of 3-Hydroxy-3-methyloxindole.
⚠️ Safety Considerations
Safety considerations for 3-Hydroxy-3-methyloxindole involve its potential hazards when handled or used in various processes. This compound should be handled with care to avoid skin or eye contact, ingestion, or inhalation of its vapors. Protective equipment such as gloves, safety goggles, and a lab coat should be worn when working with this substance to prevent any potential harm to individuals.
Furthermore, proper ventilation should be ensured when using 3-Hydroxy-3-methyloxindole to prevent the buildup of vapors in the work environment. In case of accidental exposure, immediate medical attention should be sought, and the appropriate first aid measures should be administered as needed. It is essential to follow established safety protocols and guidelines when working with this compound to minimize any risks associated with its use.
Hazard statements regarding 3-Hydroxy-3-methyloxindole include its potential harmful effects on human health if not handled properly. This compound may cause skin irritation upon contact and could be harmful if swallowed, leading to gastrointestinal disturbances. Additionally, inhalation of its vapors may cause respiratory irritation and discomfort, highlighting the need for caution when working with this substance to prevent any adverse health effects.
Precautionary statements for 3-Hydroxy-3-methyloxindole recommend using appropriate protective equipment such as gloves, safety goggles, and a lab coat when handling this compound. It is essential to work in a well-ventilated area to prevent the buildup of vapors and minimize exposure to its potentially harmful effects. In case of accidental exposure, immediate medical attention should be sought, and the relevant first aid measures should be applied as required to ensure the safety of individuals handling this substance. Following these precautionary measures is crucial when working with 3-Hydroxy-3-methyloxindole to mitigate any potential risks associated with its use.
🔬 Potential Research Directions
Research on 3-Hydroxy-3-methyloxindole could investigate its potential as a therapeutic agent in cancer treatment, due to its reported anti-tumor activity and ability to induce cell death in certain cancer cell lines.
Furthermore, studies could explore the molecular mechanisms underlying the biological effects of 3-Hydroxy-3-methyloxindole, aiming to elucidate its interactions with specific cellular targets and pathways.
Additionally, future research directions could focus on optimizing the synthesis and formulation of 3-Hydroxy-3-methyloxindole to enhance its stability, bioavailability, and overall pharmacokinetic profile for potential clinical applications.
🧪 Related Compounds
One compound similar to 3-Hydroxy-3-methyloxindole based upon molecular structure is 5-Hydroxyindole. This compound shares a similar core structure with 3-Hydroxy-3-methyloxindole, featuring a hydroxy group on the indole ring. The presence of the hydroxy group imparts similar reactivity and potential biological activities to both compounds.
Another related compound is 3-Methylindole, which shares a structural similarity with 3-Hydroxy-3-methyloxindole. While 3-Methylindole lacks the hydroxy group found in 3-Hydroxy-3-methyloxindole, the presence of the methyl group on the indole ring gives these compounds similar steric and electronic properties. This structural similarity can influence their biological activities and potential applications.
Additionally, 3-Hydroxyindole is a closely related compound to 3-Hydroxy-3-methyloxindole based on molecular structure. Both compounds feature a hydroxy group attached to the indole ring, albeit at different positions. This shared core structure imparts similar chemical properties and potential bioactivities to 3-Hydroxyindole and 3-Hydroxy-3-methyloxindole. The positional difference of the hydroxy group can lead to distinct reactivity and biological effects between these two compounds.
