2H-Azirine, a three-membered heterocycle, may not have direct relevance to everyday life in terms of common applications or consumer products. However, it is of significant interest to the scientific community due to its unique chemical properties and potential applications in the field of organic synthesis. Research on 2H-Azirine could lead to the development of new drugs, materials, and catalysts, thus impacting various industries and potentially benefiting society as a whole in the long run.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
In commercial and industrial applications, 2H-Azirine is primarily utilized as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. It is commonly employed in the production of high-value compounds due to its reactivity and versatile nature in organic synthesis. Additionally, 2H-Azirine is used in the manufacturing of specialty polymers and as a building block for the production of functional materials in the electronics industry.
In the realm of drug and medication applications, 2H-Azirine plays a crucial role as a starting material for the synthesis of biologically active compounds. Its ability to undergo various chemical transformations makes it a valuable tool in medicinal chemistry for the development of new drugs targeting specific diseases. Moreover, 2H-Azirine derivatives have shown promising potential in anti-cancer therapy and as antimicrobial agents, highlighting their importance in the pharmaceutical industry for the treatment of various medical conditions.
⚗️ Chemical & Physical Properties
2H-Azirine is a clear, colorless liquid with a fishy or ammonia-like odor. This compound is highly reactive and is commonly used in organic synthesis.
The molar mass of 2H-Azirine is approximately 57.08 g/mol, with a density of about 0.93 g/cm³. In comparison to common food items, such as sugar (molar mass of 342.30 g/mol) and water (density of 1.00 g/cm³), 2H-Azirine has a lower molar mass and density.
2H-Azirine has a melting point of around -77°C and a boiling point of approximately 46°C. These values are significantly lower compared to common food items like butter (melting point around 32°C) and water (boiling point at 100°C).
🏭 Production & Procurement
2H-Azirine is typically produced through the cyclization of N-allylamines or N-vinylamines in the presence of transition metal catalysts. This process involves the formation of a three-membered ring containing an unsaturated nitrogen atom, resulting in the desired compound.
In order to procure 2H-Azirine for research or industrial purposes, one may turn to chemical suppliers who specialize in organic compounds. These suppliers may offer 2H-Azirine in various quantities, typically in the form of a liquid or solid substance, suitable for use in a variety of applications.
Once procured, 2H-Azirine can be transported utilizing standard chemical shipping practices. Due to its reactive nature, proper precautions must be taken to ensure safe handling and storage during transportation. This may include securing the compound in appropriate containers and following relevant regulations for hazardous materials.
⚠️ Safety Considerations
Safety considerations for 2H-Azirine must be taken seriously due to its potential hazards. This compound is highly flammable and may form explosive vapors when heated. It can react violently with oxidizing agents, acids, and bases, posing a risk of fire or explosion. Proper ventilation and protective equipment should be used when handling 2H-Azirine to minimize the risk of inhalation or skin contact.
Hazard statements for 2H-Azirine include: “Highly flammable liquid and vapor,” “Causes severe skin burns and eye damage,” and “May cause respiratory irritation.” It is important to keep this compound away from heat, sparks, open flames, and other sources of ignition. Skin and eye contact should be avoided, and protective clothing, gloves, and goggles should be worn when handling 2H-Azirine to prevent injury.
Precautionary statements for 2H-Azirine include: “Keep away from heat, sparks, open flames, and other sources of ignition,” “Wear protective gloves/ clothing/ eye protection/ face protection,” and “Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.” In the event of a spill or leak, proper cleanup procedures should be followed to prevent environmental contamination. It is also important to store 2H-Azirine in a cool, dry, well-ventilated area away from incompatible substances.
🔬 Potential Research Directions
One potential research direction for 2H-Azirine is the development of novel synthetic methodologies for its preparation. This could involve exploring new reagents and catalysts to improve the efficiency and selectivity of azirine formation reactions.
Another avenue for investigation is the study of the reactivity and chemical properties of 2H-Azirine. This could include exploring its behavior in various types of reactions, as well as its potential applications in the synthesis of complex molecules such as natural products or pharmaceutical compounds. Additionally, investigations into the stereoselectivity of azirine reactions could provide valuable insight into the underlying mechanisms of these transformations.
🧪 Related Compounds
One similar compound to 2H-Azirine is Oxirane, also known as ethylene oxide. This three-membered cyclic ether consists of one oxygen atom and two carbon atoms. Oxirane is highly reactive and is commonly used as an intermediate in the production of various chemicals.
Another compound with a similar molecular structure to 2H-Azirine is Thiirane, also known as ethylene sulfide. Thiirane is a cyclic sulfur compound with two carbon atoms and one sulfur atom in its ring. This compound is less commonly encountered compared to azirines and oxiranes, but it has its own unique chemical properties and applications.
A third compound analogous to 2H-Azirine is Selenirane, also known as ethylene selenide. Selenirane is a cyclic selenium compound with two carbon atoms and one selenium atom in its ring. This compound is less stable compared to its oxygen and sulfur analogs but has attracted interest in the field of organoselenium chemistry for its potential reactivity in various transformations.