2,6-Dihydroxypyridine, also known as DHP, is a chemical compound that plays a significant role in everyday life. It is a key ingredient in the production of drugs such as molindone and tesofensine, which are utilized in the treatment of various mental health disorders and obesity, respectively. Additionally, DHP is also used in the synthesis of pesticides and herbicides that help protect crops from pests and weeds. Overall, the versatility and importance of 2,6-Dihydroxypyridine make it a crucial component in various industries that impact our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2,6-Dihydroxypyridine, also known as 2,6-pyridinediol, has several commercial and industrial applications. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. It can also be utilized as a chelating agent in metal ion extraction processes and as a precursor for the production of various polymers.
In terms of drug and medication applications, 2,6-Dihydroxypyridine has been studied for its potential therapeutic effects. Some research suggests that it may have antioxidant properties and could be useful in the treatment of neurological disorders and oxidative stress-related conditions. However, further investigation is needed to fully understand its pharmacological potential and mechanisms of action.
⚗️ Chemical & Physical Properties
2,6-Dihydroxypyridine appears as a colorless crystalline solid with no distinct odor. It is often described as having a slightly bitter taste.
The molar mass of 2,6-Dihydroxypyridine is approximately 111.1 g/mol, with a density of around 1.6 g/cm³. In comparison, common food items such as sucrose and salt have molar masses ranging from 342.3 g/mol to 58.44 g/mol, and densities ranging from 1.59 g/cm³ to 2.16 g/cm³.
The melting point of 2,6-Dihydroxypyridine is typically around 172-174°C, while the boiling point is approximately 374-378°C. These values are higher than typical food items like sugar (melting point: 160-186°C) and water (boiling point: 100°C).
2,6-Dihydroxypyridine is soluble in water, forming a clear solution. It has a relatively low viscosity, making it easy to dissolve in liquids. In contrast, common food items like sugar and salt are also soluble in water, but may have varying viscosities depending on concentration.
🏭 Production & Procurement
2,6-Dihydroxypyridine, a compound used in various chemical reactions and pharmaceutical applications, is typically produced through chemical synthesis. This process involves the reaction of a suitable precursor compound with an oxidizing agent to form the desired product. The purification of 2,6-Dihydroxypyridine is crucial to remove any impurities and ensure a high-quality final product.
In terms of procurement, 2,6-Dihydroxypyridine can be acquired from chemical suppliers or manufacturers specializing in fine chemicals. The compound is often available in both bulk quantities and smaller amounts for research purposes. Transportation of 2,6-Dihydroxypyridine is typically done in sealed containers to prevent any leakage or contamination during transit.
When procuring 2,6-Dihydroxypyridine, it is important to consider the regulations regarding its handling and storage. Proper labeling and documentation are essential when transporting the compound to ensure compliance with safety standards. Additionally, proper storage conditions, such as keeping the compound in a cool, dry place away from direct sunlight, should be maintained to preserve its stability and quality.
⚠️ Safety Considerations
Safety considerations for 2,6-Dihydroxypyridine include its potential hazards when ingested, inhaled, or in contact with skin or eyes. This chemical compound is known to be harmful if swallowed, causing irritation and damage to the gastrointestinal tract. It can also cause irritation to the respiratory system if inhaled, leading to coughing, shortness of breath, and chest pain. Moreover, direct skin or eye contact with 2,6-Dihydroxypyridine can result in irritation, redness, and even chemical burns.
Hazard statements for 2,6-Dihydroxypyridine include its classification as harmful if swallowed, causing damage to organs. It is also identified as irritating to the respiratory system, skin, and eyes. In addition, prolonged or repeated exposure to 2,6-Dihydroxypyridine may result in serious health effects, such as dermatitis, asthma, or other respiratory disorders. It is essential to handle this compound with caution and adhere to proper safety protocols to minimize the risk of harm.
Precautionary statements for 2,6-Dihydroxypyridine emphasize the importance of wearing personal protective equipment, such as gloves, goggles, and a respiratory mask, when handling this chemical compound. It is recommended to work in a well-ventilated area to prevent exposure through inhalation. In case of skin or eye contact, immediate rinsing with water is necessary to minimize the effects of irritation or burns. Furthermore, storing 2,6-Dihydroxypyridine in a secure and properly labeled container is crucial to avoid accidental ingestion or contact.
🔬 Potential Research Directions
Research on 2,6-Dihydroxypyridine has shown promise in the field of medicinal chemistry due to its potential antioxidant and anti-inflammatory properties. Future studies may explore its therapeutic potential in the treatment of various diseases, such as neurodegenerative disorders and cancer.
Furthermore, the investigation of the pharmacological activities of 2,6-Dihydroxypyridine could lead to the development of novel drug candidates with improved efficacy and safety profiles. Its chemical structure also suggests potential applications in the synthesis of biologically active compounds, making it a valuable target for organic chemists.
Moreover, studies focusing on the mechanisms of action of 2,6-Dihydroxypyridine could provide valuable insights into its biological activities and interactions with cellular targets. This research could contribute to a better understanding of its pharmacokinetic and pharmacodynamic properties, paving the way for the development of new therapeutic interventions based on this compound.
🧪 Related Compounds
One similar compound to 2,6-Dihydroxypyridine is 2,3-Dihydroxypyridine. This compound shares a similar molecular structure with 2,6-Dihydroxypyridine, but differs in the position of one of the hydroxyl groups. The presence of two hydroxyl groups on the pyridine ring confers similar chemical properties to both compounds.
Another similar compound is 2,5-Dihydroxypyridine. Like 2,6-Dihydroxypyridine, this compound contains two hydroxyl groups attached to a pyridine ring. The difference lies in the position of the hydroxyl groups on the ring, which may lead to variations in biological activity or chemical reactivity.
Additionally, 3,5-Dihydroxypyridine is structurally similar to 2,6-Dihydroxypyridine with two hydroxyl groups on a pyridine ring. The placement of hydroxyl groups on the ring affects the compound’s properties, such as solubility, stability, and potential interactions with other molecules. Studying these similar compounds provides insight into the structure-activity relationships of pyridine derivatives in various chemical and biological processes.
