2′,5′-Dihydroxyacetophenone, also known as DHA, is a chemical compound that has several practical applications in everyday life. This organic compound is commonly used in the production of pharmaceuticals, especially as a starting material in the synthesis of various drugs. Additionally, DHA is utilized in the manufacturing of cosmetic products, such as hair dyes and skin creams. Its antioxidant properties also make it a popular ingredient in the formulation of anti-aging skincare products. Overall, 2′,5′-Dihydroxyacetophenone plays a significant role in the development of various consumer goods that are widely utilized by individuals on a daily basis.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2′,5′-Dihydroxyacetophenone, commonly known as DHA, is a compound with various commercial and industrial applications. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances due to its versatile chemical structure. DHA’s unique properties make it a valuable building block for the production of a wide range of compounds used in various industries.
In the pharmaceutical industry, 2′,5′-Dihydroxyacetophenone is utilized in the synthesis of antibiotics, antiviral drugs, and anti-inflammatory medications. Its ability to serve as a precursor for the creation of more complex molecules makes it an essential component in the development of therapeutically important compounds. Additionally, DHA has shown potential in the treatment of neurological disorders due to its ability to inhibit certain enzymes involved in disease progression.
In addition to its role in pharmaceuticals, 2′,5′-Dihydroxyacetophenone is used in the formulation of cosmetics, flavors, and fragrances. Its aromatic properties make it an attractive option for enhancing the scent of various products, while its chemical reactivity allows for the creation of custom blends tailored to specific applications. Overall, DHA’s versatility and utility in a variety of industries make it a valuable compound with numerous commercial and industrial applications.
⚗️ Chemical & Physical Properties
2′,5′-Dihydroxyacetophenone is a white crystalline compound with a faint, sweet odor. It is commonly used in the production of pharmaceuticals and fragrances due to its aromatic properties.
The molar mass of 2′,5′-Dihydroxyacetophenone is approximately 152.15 g/mol, and it has a density of 1.21 g/cm³. Compared to common food items, such as sugar (180.16 g/mol) and salt (58.44 g/mol), 2′,5′-Dihydroxyacetophenone has a lower molar mass and higher density.
2′,5′-Dihydroxyacetophenone has a melting point of 121-124°C and a boiling point of 367-368°C. In comparison, common food items like butter (melting point of 32-35°C) and water (boiling point of 100°C) have lower melting and boiling points.
This compound is sparingly soluble in water but soluble in organic solvents, like ethanol and acetone. It has a low viscosity, making it easily mixable in solutions compared to common food items like honey, which has high viscosity and limited solubility in water.
🏭 Production & Procurement
2′,5′-Dihydroxyacetophenone is primarily produced through chemical synthesis in laboratory settings. This process typically involves the oxidation of phenol using a suitable oxidizing agent, followed by acylation with acetic anhydride to yield the desired product. The reaction conditions, such as temperature and pressure, must be carefully controlled to ensure the formation of 2′,5′-Dihydroxyacetophenone.
Once 2′,5′-Dihydroxyacetophenone is synthesized, it can be procured through specialized chemical suppliers or pharmaceutical companies. The compound is often available in both liquid and solid forms, depending on the specific application. When procuring this compound, it is essential to ensure that the purity levels meet the required standards for the intended use.
In terms of transportation, 2′,5′-Dihydroxyacetophenone is typically shipped in sealed containers to prevent contamination or degradation during transit. The compound is considered stable under normal storage conditions but may degrade if exposed to extreme temperatures or light. Proper labeling and documentation are crucial when transporting 2′,5′-Dihydroxyacetophenone to ensure compliance with regulations and safe handling practices.
⚠️ Safety Considerations
Safety Considerations for 2′,5′-Dihydroxyacetophenone:
When handling 2′,5′-Dihydroxyacetophenone, it is essential to wear appropriate personal protective equipment, such as gloves and goggles, to protect the skin and eyes from potential contact with the chemical. Additionally, proper ventilation should be ensured in the area where 2′,5′-Dihydroxyacetophenone is being used to prevent inhalation of any vapors or fumes. It is also crucial to store this compound in a cool, dry place away from direct sunlight and incompatible materials to avoid any potential reactions or hazards.
Hazard Statements for 2′,5′-Dihydroxyacetophenone:
2′,5′-Dihydroxyacetophenone may be harmful if swallowed, inhaled, or absorbed through the skin. It may cause irritation to the skin, eyes, and respiratory system upon contact, leading to redness, itching, or difficulty breathing. Long-term exposure to this compound may result in more severe health effects, such as organ damage or respiratory issues. Therefore, it is important to handle 2′,5′-Dihydroxyacetophenone with caution and follow all safety protocols to minimize the risk of harm.
Precautionary Statements for 2′,5′-Dihydroxyacetophenone:
To prevent exposure to 2′,5′-Dihydroxyacetophenone, it is recommended to wear protective gloves, clothing, and eyewear when handling this compound. In case of contact with the skin, eyes, or clothing, it is advised to rinse thoroughly with water and seek medical attention if irritation persists. If ingested or inhaled, immediate medical attention should be sought, and the affected individual should be removed from the contaminated area to fresh air. Proper storage and disposal of 2′,5′-Dihydroxyacetophenone should also be observed to prevent any accidental spills or leaks that could lead to environmental contamination.
🔬 Potential Research Directions
One potential research direction for 2′,5′-Dihydroxyacetophenone is its role as a natural product with potential pharmaceutical applications. Studies could explore its bioactivity and pharmacological properties, particularly its potential as an antimicrobial agent or antioxidant.
Another avenue of research could focus on the synthesis and characterization of derivatives of 2′,5′-Dihydroxyacetophenone. By modifying the structure of the compound, researchers could investigate how these changes affect its biological activity or enhance its potential for use in pharmaceuticals or biotechnology.
Furthermore, investigations into the mechanism of action of 2′,5′-Dihydroxyacetophenone could provide valuable insights into its interactions with biological systems. Understanding how this compound exerts its biological effects could lead to the development of more potent derivatives or novel applications in medicine or biotechnology.
🧪 Related Compounds
One similar compound to 2′,5′-Dihydroxyacetophenone based on molecular structure is 2′,4′-Dihydroxyacetophenone. This compound differs from 2′,5′-Dihydroxyacetophenone by having hydroxyl groups attached at the 2′ and 4′ positions on the phenyl ring instead of at the 2′ and 5′ positions. Despite this difference, both compounds share similar chemical properties due to the presence of hydroxyl groups on the aromatic ring.
Another compound with a molecular structure similar to 2′,5′-Dihydroxyacetophenone is 2′,6′-Dihydroxyacetophenone. In this compound, hydroxyl groups are attached at the 2′ and 6′ positions on the phenyl ring, differing from the positioning in 2′,5′-Dihydroxyacetophenone. Despite this difference in position, both compounds share similarities in their chemical behavior and potential applications in various fields.
Additionally, a compound known as 3′,4′-Dihydroxyacetophenone is structurally similar to 2′,5′-Dihydroxyacetophenone. In this compound, hydroxyl groups are located at the 3′ and 4′ positions on the phenyl ring, distinct from the positioning in 2′,5′-Dihydroxyacetophenone. Despite this structural difference, both compounds share similarities in terms of chemical properties and potential uses in pharmaceutical, chemical, and biological research.
