2,4,5-Trimethylphenol, commonly known as cresol, is a crucial compound with various applications in everyday life. It is commonly used in the manufacturing of disinfectants, pesticides, and industrial cleaners due to its strong antimicrobial properties. Additionally, cresol is utilized in the production of fragrances, flavorings, and pharmaceuticals. Its presence in these products contributes to their effectiveness in killing harmful bacteria and viruses, ultimately benefiting public health and overall cleanliness. Therefore, 2,4,5-Trimethylphenol plays a significant role in maintaining a hygienic and safe environment in our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2,4,5-Trimethylphenol, also known as 2,4,5-tmp, is commonly used in a variety of commercial and industrial applications. One of its main uses is as a chemical intermediate in the production of antioxidants, fragrances, and pharmaceuticals due to its stability and reactivity. Additionally, 2,4,5-Trimethylphenol is utilized as a corrosion inhibitor in industries such as manufacturing and oil production.
In the realm of drug and medication applications, 2,4,5-Trimethylphenol has shown promise as an antifungal agent due to its potent antimicrobial properties. It has been used in some topical antifungal medications to treat conditions such as ringworm and athlete’s foot. Furthermore, research is ongoing to explore the potential of 2,4,5-Trimethylphenol in combating bacterial infections and developing new antibiotics.
⚗️ Chemical & Physical Properties
2,4,5-Trimethylphenol, also known as hemimellitole, is a white crystalline solid with a distinct odor resembling that of creosote. It is commonly used as a fragrance ingredient in various products due to its strong odor and pleasant aroma.
With a molar mass of approximately 150.21 g/mol and a density of 0.996 g/cm³, 2,4,5-Trimethylphenol is comparable in molar mass to sucrose (342.3 g/mol) and in density to olive oil (0.92 g/cm³). Its properties make it relatively lightweight and easily soluble in organic solvents.
The melting point of 2,4,5-Trimethylphenol is around 62-65°C, while its boiling point ranges from 210-212°C. In comparison, common food items like sugar have a melting point of 186°C and a boiling point well above 1600°C. This indicates that 2,4,5-Trimethylphenol has relatively lower melting and boiling points.
2,4,5-Trimethylphenol has limited solubility in water, with a reported value of 0.15 mg/L. Additionally, it exhibits low viscosity due to its molecular structure. In contrast, common food items like salt are highly soluble in water and exhibit varying levels of viscosity, making 2,4,5-Trimethylphenol distinct in its solubility and viscosity characteristics.
🏭 Production & Procurement
2,4,5-Trimethylphenol is typically produced through a process known as alkylation, in which phenol is reacted with a mixture of propylene and isobutylene in the presence of an acid catalyst. This reaction leads to the formation of 2,4,5-Trimethylphenol, which is then separated from the reaction mixture through distillation.
Once produced, 2,4,5-Trimethylphenol can be procured from chemical suppliers who specialize in the production and distribution of specialty chemicals. It is commonly transported in either liquid form in drums or bulk containers, or in solid form as flakes or powder in bags. Transportation of this compound is carried out in compliance with regulations governing the handling and transportation of hazardous chemicals.
The procurement and transport of 2,4,5-Trimethylphenol require careful consideration of its properties, including its potential flammability and toxicity. Proper precautions must be taken to ensure the safe handling and transport of this chemical to prevent any potential accidents or hazards. It is essential to work with trained professionals and follow established safety protocols when dealing with 2,4,5-Trimethylphenol.
⚠️ Safety Considerations
Safety considerations for 2,4,5-Trimethylphenol include its potential to cause skin and eye irritation upon contact. It is also harmful if swallowed or inhaled, and may cause respiratory irritation. Therefore, appropriate personal protective equipment such as gloves and goggles should be worn when handling this chemical to prevent any adverse health effects.
In addition, 2,4,5-Trimethylphenol should be stored in a well-ventilated area away from sources of ignition. It should also be kept away from incompatible materials to prevent any potential chemical reactions. Care should be taken when transferring or handling this compound to minimize the risk of exposure and accidents.
Hazard statements for 2,4,5-Trimethylphenol include “Causes skin and eye irritation” and “Toxic if swallowed or inhaled”. It is also labeled as harmful to aquatic life with long-lasting effects. These hazard statements indicate the potential health hazards and environmental risks associated with the use and handling of 2,4,5-Trimethylphenol.
Precautionary statements for 2,4,5-Trimethylphenol include “Wear protective gloves/eye protection” and “Avoid release to the environment”. It is also recommended to handle this chemical in a well-ventilated area and avoid breathing in vapors or dust. In case of accidental exposure, immediate medical attention should be sought to minimize any potential health risks.
🔬 Potential Research Directions
One potential research direction for 2,4,5-Trimethylphenol could involve exploring its use as a precursor in the synthesis of various organic compounds. Its unique chemical structure and reactivity make it a promising candidate for the development of new materials and pharmaceuticals.
Another avenue of research could focus on investigating the environmental fate and toxicity of 2,4,5-Trimethylphenol. Understanding how this compound interacts with ecosystems and organisms can provide valuable insights into its potential impact on the environment and human health. This research could help inform regulatory decisions and risk assessments related to the use of 2,4,5-Trimethylphenol in various industrial applications.
🧪 Related Compounds
One similar compound to 2,4,5-Trimethylphenol is 2,4-Dimethylphenol, which also features a methyl group attached to the second and fourth carbon atoms of the phenol ring. This compound differs from 2,4,5-Trimethylphenol by the absence of a methyl group on the fifth carbon atom. 2,4-Dimethylphenol is commonly used in industrial applications such as the production of pharmaceuticals and pesticides.
Another comparable compound is 3,4,5-Trimethylphenol, in which three methyl groups are attached to the third, fourth, and fifth carbon atoms of the phenol ring. This compound shares a similar molecular structure with 2,4,5-Trimethylphenol, but with a different positioning of the methyl groups. 3,4,5-Trimethylphenol is often utilized in the manufacturing of fragrances and as an intermediate in the synthesis of various organic compounds.
One further analog is 2,3,4-Trimethylphenol, where methyl groups are positioned on the second, third, and fourth carbon atoms of the phenol ring. This compound possesses a structure closely related to 2,4,5-Trimethylphenol, except for the distinct placement of the methyl groups. 2,3,4-Trimethylphenol is employed in the production of antioxidants and as a chemical intermediate in the synthesis of specialty chemicals.
