2,4-Dimethoxybenzoic acid 

2,4-Dimethoxybenzoic acid serves as a key building block in the synthesis of various pharmaceuticals, agrochemicals, and dyes. Its structural versatility and wide range of applications make it a crucial component in several industries. As such, its relevance extends to everyday life through its contribution to the development of essential products that play a role in human health, agriculture, and manufacturing.

Table of Contents:

💡  Commercial Applications

2,4-Dimethoxybenzoic acid, also known as veratric acid, has several commercial and industrial applications. It is commonly used as a precursor in the synthesis of various pharmaceuticals, agrochemicals, and fragrances due to its versatile chemical structure. Additionally, veratric acid is utilized in the manufacturing of dyes and polymers, as well as in the food industry as a flavoring agent.

In terms of drug and medication applications, 2,4-Dimethoxybenzoic acid has shown potential as an anti-inflammatory and antioxidant agent. Studies have suggested that veratric acid may possess neuroprotective properties and could be beneficial in the treatment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Furthermore, veratric acid has demonstrated antimicrobial activity, making it a promising candidate for the development of new antibiotics and antimicrobial agents.

⚗️  Chemical & Physical Properties

2,4-Dimethoxybenzoic acid is a white crystalline solid that is odorless. It has a molecular formula C9H10O4 and a molecular weight of 182.18 g/mol.

The molar mass of 2,4-Dimethoxybenzoic acid is similar to common food items such as sucrose (table sugar) which has a molar mass of 342.3 g/mol. However, its density is significantly lower compared to common food items like olive oil which has a density of 0.92 g/cm3.

2,4-Dimethoxybenzoic acid has a melting point of 172-174 °C and a boiling point of 385 °C. These values are higher than common food items such as butter which melts around 32-35 °C.

2,4-Dimethoxybenzoic acid is sparingly soluble in water and has a low viscosity. This contrasts with common food items like salt which is highly soluble in water and has a higher viscosity when dissolved.

🏭  Production & Procurement

2,4-Dimethoxybenzoic acid, also known as veratric acid, is typically produced through a reaction between veratraldehyde and an alkali metal hydroxide. This process involves the formation of a carboxylic acid group from the aldehyde group present in veratraldehyde.

One method of procuring 2,4-Dimethoxybenzoic acid is through the purchase of commercially available chemical reagents. These reagents can be obtained from reputable chemical suppliers or manufacturers. Once obtained, the compounds can be reacted in a controlled laboratory setting to synthesize the desired product.

Transportation of 2,4-Dimethoxybenzoic acid is typically done in compliance with international regulations for the transportation of hazardous chemicals. The compound is usually packaged in appropriate containers and transported using approved carriers to ensure safety during transit. It is important to follow all guidelines to prevent any accidents or mishaps during transportation.

⚠️  Safety Considerations

Safety Considerations for 2,4-Dimethoxybenzoic acid:

When handling 2,4-Dimethoxybenzoic acid, it is important to wear appropriate personal protective equipment including gloves, goggles, and a laboratory coat to prevent skin and eye contact. In case of ingestion, rinse mouth with water and seek medical attention immediately. It is essential to work in a well-ventilated area to avoid inhalation of fumes or vapors.

Hazard Statements for 2,4-Dimethoxybenzoic acid:

2,4-Dimethoxybenzoic acid may cause skin irritation and serious eye damage. It is harmful if swallowed, inhaled, or absorbed through the skin. This compound may cause respiratory irritation and could be harmful to aquatic life.

Precautionary Statements for 2,4-Dimethoxybenzoic acid:

When handling 2,4-Dimethoxybenzoic acid, it is important to wear protective gloves and eye protection. Avoid breathing in vapors, mist, or gas. In case of skin contact, immediately wash with plenty of soap and water. It is recommended to handle this compound in a fume hood to minimize exposure.

🔬  Potential Research Directions

Research on 2,4-Dimethoxybenzoic acid may focus on its potential biological activities and pharmacological properties. Investigations can delve into its ability to inhibit certain enzymes or receptors, as well as its potential as a lead compound for drug development.

Furthermore, studies may explore the synthesis and modification of 2,4-Dimethoxybenzoic acid derivatives to enhance its efficacy or specificity. By making structural changes to the compound, researchers can optimize its pharmacokinetic properties and biological activity, leading to the development of novel therapeutic agents.

Additionally, research could investigate the environmental fate and impact of 2,4-Dimethoxybenzoic acid. Studies may examine its degradation pathways, bioaccumulation potential, and ecological effects to better understand its environmental behavior and potential risks associated with its presence in the ecosystem.

One similar compound to 2,4-Dimethoxybenzoic acid is 3,5-Dimethoxybenzoic acid. This compound differs from 2,4-Dimethoxybenzoic acid by the position of the methoxy groups on the benzene ring. In 3,5-Dimethoxybenzoic acid, the methoxy groups are located at the meta positions, as opposed to the para positions in 2,4-Dimethoxybenzoic acid.

Another similar compound is 2,5-Dimethoxybenzoic acid. Like 2,4-Dimethoxybenzoic acid, this compound contains two methoxy groups attached to a benzene ring. However, in 2,5-Dimethoxybenzoic acid, the methoxy groups are situated at the ortho positions relative to each other, rather than the para positions as in 2,4-Dimethoxybenzoic acid.

Additionally, 3,4-Dimethoxybenzoic acid is another compound that shares structural similarities with 2,4-Dimethoxybenzoic acid. In this compound, the methoxy groups are located at the meta positions on the benzene ring. This slight variation in the positioning of the methoxy groups results in different chemical and physical properties compared to 2,4-Dimethoxybenzoic acid.

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