2,3,4,5,6-Pentafluoroaniline is a chemical compound that has relevance in various industries and research fields. This compound is commonly used in the pharmaceutical industry for synthesizing new drugs, as well as in the development of agrochemicals and dyes. Additionally, 2,3,4,5,6-Pentafluoroaniline is utilized in material sciences for the production of specialized polymers and coatings. Despite its technical nature, the compound plays a crucial role in enhancing everyday life through its applications in different products and technologies.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2,3,4,5,6-Pentafluoroaniline, a compound used in various commercial and industrial applications, is primarily utilized as a building block in the synthesis of pharmaceuticals, agrochemicals, and materials. Its unique chemical properties make it a valuable reagent in the manufacture of dyes, polymers, and specialty chemicals.
In the realm of drug and medication applications, 2,3,4,5,6-Pentafluoroaniline is employed as an intermediate in the synthesis of pharmaceutical compounds. Its role in drug development lies in its ability to serve as a precursor for the creation of potent and selective pharmacological agents with therapeutic benefits. Additionally, this compound plays a vital role in medicinal chemistry research, aiding in the discovery of novel drug candidates for various medical conditions.
⚗️ Chemical & Physical Properties
2,3,4,5,6-Pentafluoroaniline, a chemical compound often used in organic synthesis, appears as a white crystalline solid with no discernible odor. Its lack of odor makes it suitable for use in research and manufacturing processes where odor contamination is a concern.
With a molar mass of approximately 161.04 g/mol and a density of around 1.938 g/cm³, 2,3,4,5,6-Pentafluoroaniline is heavier and denser than most common food items. For comparison, the molar mass of glucose is 180.16 g/mol, and the density of water is 1 g/cm³.
2,3,4,5,6-Pentafluoroaniline has a melting point of 37-39°C and a boiling point of approximately 65-70°C. These values are considerably lower than those of most common food items, making it easier to handle and manipulate in a laboratory setting.
This compound is sparingly soluble in water, forming a clear solution when dissolved. Its low solubility in water contrasts with common food items like sugar or salt, which dissolve readily in aqueous solutions. Additionally, 2,3,4,5,6-Pentafluoroaniline has a relatively low viscosity, allowing it to flow more easily compared to thicker food items like honey or syrup.
🏭 Production & Procurement
2,3,4,5,6-Pentafluoroaniline, a compound with five fluorine atoms attached to an aniline ring, is typically produced through a multistep synthesis process. The synthesis usually involves the reaction of aniline with pentafluoronitrobenzene in the presence of reducing agents and catalysts to yield the desired product.
To procure 2,3,4,5,6-Pentafluoroaniline, one must typically contact chemical suppliers specializing in fluorinated compounds. The compound is often available in varying purities and quantities, depending on the supplier. Transporting 2,3,4,5,6-Pentafluoroaniline is usually done in sealed containers to prevent contamination or degradation during shipping.
When procuring 2,3,4,5,6-Pentafluoroaniline, it is essential to adhere to safety protocols and regulations for handling and storage. Due to its reactive nature and potential health hazards, proper precautions must be taken during transport and storage to ensure the safety of personnel and prevent environmental harm. It is advisable to work with experienced chemical handlers or consult with safety experts when dealing with 2,3,4,5,6-Pentafluoroaniline.
⚠️ Safety Considerations
Safety considerations for 2,3,4,5,6-Pentafluoroaniline include its potential to cause skin and eye irritation upon contact. Therefore, it is crucial to use appropriate personal protective equipment such as gloves and goggles when handling this compound. In addition, proper ventilation should be ensured to prevent inhalation of vapors.
It is important to note that 2,3,4,5,6-Pentafluoroaniline may also pose a risk of environmental harm if released into the surroundings. Therefore, measures should be taken to prevent spills and leaks, and any waste containing this compound should be properly disposed of according to regulations. Furthermore, fire hazards should be considered, and appropriate fire-fighting measures should be in place in case of accidental ignition.
Hazard statements for 2,3,4,5,6-Pentafluoroaniline include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential for harm if this compound comes into contact with the skin or eyes. It is important to handle 2,3,4,5,6-Pentafluoroaniline with caution and to use protective equipment to minimize the risk of skin and eye irritation.
Precautionary statements for 2,3,4,5,6-Pentafluoroaniline include “Wear protective gloves/eye protection” and “IF ON SKIN: Wash with plenty of soap and water.” These statements highlight the importance of wearing appropriate personal protective equipment and taking necessary precautions to prevent skin contact. In case of skin exposure, immediate action should be taken to wash off the compound with soap and water to minimize potential effects.
🔬 Potential Research Directions
Research on 2,3,4,5,6-Pentafluoroaniline may focus on its potential applications in medicinal chemistry, due to its unique fluorine substitution pattern which could result in enhanced biological activity compared to its non-fluorinated analogues.
Further investigations could delve into the synthesis and characterization of novel 2,3,4,5,6-Pentafluoroaniline derivatives with varying functional groups to understand structure-activity relationships and potentially discover new therapeutic agents with improved efficacy and reduced side effects.
Additionally, research efforts could also explore the environmental impact of 2,3,4,5,6-Pentafluoroaniline and its derivatives, including studies on their stability, reactivity, and potential for bioaccumulation in aquatic and terrestrial ecosystems.
🧪 Related Compounds
1,2,3,4,5-Hexafluoroaniline is a similar compound to 2,3,4,5,6-Pentafluoroaniline based on molecular structure. In 1,2,3,4,5-Hexafluoroaniline, there are six fluorine atoms attached to the benzene ring. This compound exhibits similar chemical properties to 2,3,4,5,6-Pentafluoroaniline due to the presence of multiple fluorine atoms.
2,3,4,5-Tetrafluoroaniline is another compound that shares similarities with 2,3,4,5,6-Pentafluoroaniline based on molecular structure. In 2,3,4,5-Tetrafluoroaniline, there are four fluorine atoms attached to the benzene ring. This compound may exhibit similar reactivity and chemical behavior to 2,3,4,5,6-Pentafluoroaniline due to the presence of fluorine atoms.
3,4,5,6-Tetrafluoroaniline is yet another compound that bears resemblance to 2,3,4,5,6-Pentafluoroaniline based on molecular structure. In 3,4,5,6-Tetrafluoroaniline, there are four fluorine atoms attached to the benzene ring. This compound may display comparable properties to 2,3,4,5,6-Pentafluoroaniline due to the similarity in the arrangement of fluorine atoms on the aromatic ring.
