2,3,3-Trimethyl-2-butanol is a compound used in various applications such as perfumes, flavoring agents, and as a solvent in the pharmaceutical industry. Its pleasant odor makes it a popular choice for fragrances, while its ability to dissolve other substances makes it useful in a range of products. This compound may not be familiar to the average person, but its presence in everyday items highlights the significance of organic compounds in enhancing consumer products.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2,3,3-Trimethyl-2-butanol, also known as TMBOH, has various commercial and industrial applications. It is commonly used as a solvent in the manufacturing of adhesives, coatings, and printing inks. Additionally, TMBOH is utilized as a fragrance ingredient in perfumes and personal care products due to its pleasant odor profile.
In the realm of drug and medication applications, 2,3,3-Trimethyl-2-butanol plays a crucial role as a chiral auxiliary in the synthesis of pharmaceutical compounds. Its unique properties enable efficient asymmetric synthesis, leading to the production of enantiomerically pure drugs. Furthermore, TMBOH is employed as a stabilizer in certain pharmaceutical formulations to enhance drug shelf life and stability.
⚗️ Chemical & Physical Properties
2,3,3-Trimethyl-2-butanol is a colorless liquid with a characteristic sweet, floral odor. The odor of this compound can be described as pleasant and reminiscent of lavender or violets.
The molar mass of 2,3,3-Trimethyl-2-butanol is approximately 102.17 g/mol, with a density of about 0.83 g/cm3. When compared to common food items, this compound has a lower molar mass than sucrose (table sugar) and a higher density than vegetable oil.
The melting point of 2,3,3-Trimethyl-2-butanol is around -25°C, while the boiling point is approximately 102°C. In comparison to common food items, this compound has a lower melting point than butter and a higher boiling point than water.
2,3,3-Trimethyl-2-butanol is insoluble in water but soluble in organic solvents. It has a relatively low viscosity, making it flow easily. When compared to common food items, this compound is similar in solubility to oil and has a lower viscosity than honey.
🏭 Production & Procurement
2,3,3-Trimethyl-2-butanol, also known as TMB, is typically produced through the hydration of 2,3-dimethyl-2-butene. This reaction is commonly catalyzed by strong acids, such as sulfuric acid or hydrochloric acid, which facilitate the addition of water to the double bond in the starting material.
The procurement of 2,3,3-Trimethyl-2-butanol involves sourcing the necessary starting materials, such as 2,3-dimethyl-2-butene and the acid catalyst, from chemical suppliers. Once these components are obtained, the production process can be carried out in a laboratory or industrial setting, depending on the scale of the desired TMB production.
After production, 2,3,3-Trimethyl-2-butanol can be transported in bulk quantities via tanker trucks or railcars to various end-users, such as manufacturers of fragrances, cosmetics, or pharmaceuticals. Care should be taken during transportation to ensure the stability and safety of the compound, as it is important to prevent spills or exposure to fire hazards.
⚠️ Safety Considerations
Safety considerations for 2,3,3-Trimethyl-2-butanol, also known as TTMB, must be taken into account when handling this chemical compound. TTMB is a colorless liquid with a strong odor and is commonly used in the production of fragrances and other industrial applications. It is important to use proper personal protective equipment when working with TTMB, including gloves, goggles, and a lab coat to prevent skin contact and inhalation of vapors. Additionally, TTMB should be stored in a cool, dry place away from direct sunlight and incompatible materials to prevent potential reactions or accidents.
Hazard statements for 2,3,3-Trimethyl-2-butanol include being harmful if swallowed, inhaled, or in contact with skin. It may cause skin irritation and serious eye irritation, and prolonged or repeated exposure may cause liver and kidney damage. TTMB is also harmful to aquatic life, with long-lasting effects on aquatic ecosystems. It is important to handle this chemical with care and follow proper safety protocols to minimize the risk of exposure and potential harm.
Precautionary statements for 2,3,3-Trimethyl-2-butanol advise users to wear protective gloves, eye protection, and a face mask when handling this chemical. It is recommended to work in a well-ventilated area to prevent inhalation of vapors and to avoid contact with skin and eyes. In case of skin irritation or exposure, it is important to wash thoroughly with soap and water and seek medical attention if necessary. TTMB should be stored in a secure area away from children, pets, and food products to prevent accidental ingestion or contamination.
🔬 Potential Research Directions
One potential research direction for 2,3,3-Trimethyl-2-butanol could involve exploring its role as a potential intermediate in organic synthesis reactions. Understanding its reactivity and potential applications in the synthesis of complex molecules could shed light on its utility in various industries.
Another avenue of research could focus on the environmental and health effects of 2,3,3-Trimethyl-2-butanol. Investigating its toxicity, biodegradability, and behavior in different environmental compartments could provide valuable insights for risk assessments and regulatory decisions. Studying its impact on human health through exposure assessments and toxicological studies could also be of interest to researchers.
🧪 Related Compounds
One similar compound to 2,3,3-Trimethyl-2-butanol is 2,3-Dimethyl-2-butanol. This compound has a similar molecular structure with one fewer methyl group attached to the second carbon atom. The presence of the hydroxyl group on the second carbon atom gives the compound its alcohol functionality.
Another similar compound is 2,2-Dimethyl-1-propanol. In this compound, the methyl groups are attached to the first and second carbon atoms instead of the second and third carbon atoms. The presence of the hydroxyl group on the first carbon atom gives the compound its alcohol functionality. This compound shares similarities in molecular structure with 2,3,3-Trimethyl-2-butanol due to the presence of methyl groups on adjacent carbon atoms.
Additionally, 3,3-Dimethyl-1-butanol is structurally similar to 2,3,3-Trimethyl-2-butanol. In this compound, the methyl groups are attached to the third and fourth carbon atoms, and the hydroxyl group is attached to the third carbon atom. The positioning of the methyl groups and the hydroxyl group gives this compound its alcohol functionality, similar to 2,3,3-Trimethyl-2-butanol. These compounds share structural similarities due to the branching pattern of the carbon chain.