2-Vinylpyridine is a chemical compound that is commonly utilized in the production of adhesives, coatings, and resins. Its relevance to everyday life lies in its versatile applications in various industries such as pharmaceuticals, plastics, and electronics. 2-Vinylpyridine is a key building block for creating polymers with unique properties, making it essential for the development of a wide range of consumer products that we use on a daily basis. Its impact on everyday life is therefore significant, despite being less widely recognized by the general public.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Vinylpyridine, a chemical compound with the formula C7H7N, is commonly used in both commercial and industrial applications. In industry, it is utilized as a monomer in the production of polymers such as poly(2-vinylpyridine) and copolymers with other vinyl monomers. Its versatile nature allows for applications in adhesives, coatings, and specialty chemicals.
Furthermore, 2-Vinylpyridine plays a significant role in the pharmaceutical industry. It is used as a precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug molecules. By incorporating 2-Vinylpyridine into the chemical structure of medications, researchers can enhance their therapeutic properties and improve drug efficacy. Its unique chemical properties make it a valuable building block for drug development.
⚗️ Chemical & Physical Properties
2-Vinylpyridine is a colorless to pale yellow liquid with a strong, musty odor resembling that of garlic or stale beer. This compound is commonly used in the production of polymers and pharmaceuticals due to its reactive vinyl group.
With a molar mass of 105.14 g/mol and a density of 0.967 g/cm³, 2-Vinylpyridine has properties that are similar to common food items such as glucose (molar mass of 180.16 g/mol) and olive oil (density of 0.92 g/cm³).
The melting point of 2-Vinylpyridine is -33°C, while its boiling point is 128°C. These values differ from those of common food items such as sugar (melting point of 186°C) and water (boiling point of 100°C).
2-Vinylpyridine is sparingly soluble in water and has a low viscosity. In comparison, common food items like salt are highly soluble in water, while honey has a higher viscosity.
🏭 Production & Procurement
2-Vinylpyridine is primarily produced through the reaction of acrylonitrile with formaldehyde and ammonia. This synthesis process results in the formation of 2-Vinylpyridine, which is then isolated and purified for commercial use.
The procurement of 2-Vinylpyridine typically involves ordering the compound from chemical suppliers or manufacturers. It is commonly available in bulk quantities and can be transported in sealed containers to ensure its stability during transit.
Upon arrival, 2-Vinylpyridine should be stored in a cool, dry place away from heat and sources of ignition. Proper labeling and handling procedures should be followed to prevent any accidents or contamination. Manufacturers and researchers alike must adhere to safety protocols when working with this chemical compound.
⚠️ Safety Considerations
Safety considerations for 2-Vinylpyridine must be taken into account due to its potential hazards. This compound is highly flammable and may form explosive peroxides when exposed to air. It is also harmful if swallowed, inhaled, or absorbed through the skin. Special precautions should be taken when handling 2-Vinylpyridine, including the use of appropriate personal protective equipment such as gloves, goggles, and a lab coat. Additionally, this compound should only be used in a well-ventilated area to minimize the risk of exposure.
The hazard statements for 2-Vinylpyridine include: “Highly flammable liquid and vapor,” “May form explosive peroxides,” “Harmful if swallowed,” “Harmful if inhaled,” and “Harmful if absorbed through the skin.” These statements highlight the various ways in which 2-Vinylpyridine can pose a risk to human health and safety. It is important to be aware of these hazards and take appropriate precautions when working with this compound.
Precautionary statements for 2-Vinylpyridine include: “Keep away from heat/sparks/open flames/hot surfaces – No smoking,” “Avoid breathing dust/fume/gas/mist/vapors/spray,” “Wear protective gloves/protective clothing/eye protection/face protection,” “IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician,” and “IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.” These statements emphasize the importance of following recommended safety practices to minimize the risk of exposure to 2-Vinylpyridine and prevent potential harm.
🔬 Potential Research Directions
Research on 2-Vinylpyridine has shown its potential as a building block in the synthesis of various compounds due to its vinyl group. This compound has been explored for its reactivity in cross-coupling reactions and as a ligand in coordination chemistry studies.
Further studies could focus on the development of new catalytic processes using 2-Vinylpyridine as a key component. Its versatility in reactions such as Heck, Suzuki-Miyaura, and Sonogashira couplings make it a promising candidate for expanding the scope of synthetic methodologies.
Additionally, research could investigate the biological activity of 2-Vinylpyridine and its derivatives. Understanding the interaction of this compound with biological targets could lead to the development of new pharmaceuticals or agrochemicals with enhanced efficacy.
🧪 Related Compounds
2-Vinylpyridine belongs to a class of compounds known as vinylpyridines, which are characterized by the presence of a vinyl group (CH=CH2) attached to a pyridine ring. Similar compounds to 2-Vinylpyridine include 2-Ethylpyridine, which has an ethyl group (CH3CH2-) attached to the pyridine ring instead of a vinyl group. This substitution results in a slightly different chemical reactivity and physical properties compared to 2-Vinylpyridine.
Another similar compound is 3-Vinylpyridine, which shares the same pyridine ring structure as 2-Vinylpyridine but with the vinyl group attached to a different carbon atom. This subtle difference in the position of the vinyl group can lead to variations in the compound’s behavior in chemical reactions and overall stability. Like 2-Vinylpyridine, 3-Vinylpyridine is commonly used in organic synthesis and as a building block for various compounds.
Additionally, 4-Vinylpyridine is another compound related to 2-Vinylpyridine, with the vinyl group attached to the fourth carbon atom of the pyridine ring. This compound also exhibits similar chemical properties and reactivity as 2-Vinylpyridine but may have different applications in organic chemistry and material sciences due to its structural variation. The study of these closely related compounds helps researchers understand the effects of subtle structural changes on a molecule’s behavior and properties.
